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Total number of protein in "GO:0070588" GO term:  117

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ANO6-201 ANO6 Q4KMQ2 Anoctamin-6 chr12 GO:0070588 Not Cancer Driver No 92 0.1010989010989011 80 9 0.0098901098901098 0
ANXA2-204 ANXA2 P07355 Annexin A2 chr15 GO:0070588 Not Cancer Driver No 38 0.1120943952802359 21 2 0.0058997050147492 0
ANXA6-201 ANXA6 P08133 Annexin A6 chr5 GO:0070588 Not Cancer Driver No 63 0.0936106983655274 107 12 0.0178306092124814 0
ANXA9-201 ANXA9 O76027 Annexin A9 chr1 GO:0070588 Not Cancer Driver No 35 0.1014492753623188 42 5 0.0144927536231884 0
ASIC1-202 ASIC1 P78348 Acid-sensing ion channel 1 chr12 GO:0070588 Not Cancer Driver No 62 0.1174242424242424 17 2 0.0037878787878787 0
ATP2A1-201 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 GO:0070588 Not Cancer Driver No 125 0.1248751248751248 80 9 0.0089910089910089 1
ATP2A2-204 ATP2A2 P16615 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 chr12 GO:0070588 Not Cancer Driver No 106 0.1017274472168906 78 13 0.0124760076775431 40
ATP2A3-205 ATP2A3 Q93084 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 chr17 GO:0070588 Not Cancer Driver No 92 0.0920920920920921 147 13 0.013013013013013 0
ATP2B2-202 ATP2B2 Q01814 Plasma membrane calcium-transporting ATPase 2 chr3 GO:0070588 Not Cancer Driver No 206 0.165728077232502 362 68 0.0547063555913113 0
ATP2B4-203 ATP2B4 P23634 Plasma membrane calcium-transporting ATPase 4 chr1 GO:0070588 Not Cancer Driver No 113 0.0937759336099585 264 20 0.0165975103734439 0
ATP2C1-218 ATP2C1 P98194 Calcium-transporting ATPase type 2C member 1 chr3 GO:0070588 Not Cancer Driver No 84 0.0914036996735582 44 6 0.0065288356909684 19
ATP2C2-201 ATP2C2 O75185 Calcium-transporting ATPase type 2C member 2 chr16 GO:0070588 Not Cancer Driver No 95 0.1004228329809725 54 5 0.0052854122621564 0
CACHD1-206 CACHD1 Q5VU97 VWFA and cache domain-containing protein 1 chr1 GO:0070588 Not Cancer Driver No 124 0.097331240188383 206 25 0.0196232339089481 0
CACNA1A-201 CACNA1A O00555 Voltage-dependent P/Q-type calcium channel subunit alpha-1A chr19 GO:0070588 Not Cancer Driver No 306 0.1221069433359936 1139 98 0.0391061452513966 46
CACNA1C-220 CACNA1C Q13936 Voltage-dependent L-type calcium channel subunit alpha-1C chr12 GO:0070588 Not Cancer Driver No 350 0.1637043966323667 708 123 0.0575304022450888 25
CACNA1D-202 CACNA1D Q01668 Voltage-dependent L-type calcium channel subunit alpha-1D chr3 GO:0070588 Census, Compendium Yes 227 0.1050439611291069 736 83 0.0384081443776029 5
CACNA1G-204 CACNA1G O43497 Voltage-dependent T-type calcium channel subunit alpha-1G chr17 GO:0070588 Not Cancer Driver No 263 0.1106436684896928 1026 106 0.0445940260832982 3
CACNA1S-201 CACNA1S Q13698 Voltage-dependent L-type calcium channel subunit alpha-1S chr1 GO:0070588 Not Cancer Driver No 287 0.1532301121195942 386 60 0.0320341697810998 4
CACNA2D2-206 CACNA2D2 Q9NY47 Voltage-dependent calcium channel subunit alpha-2/delta-2 chr3 GO:0070588 Not Cancer Driver No 92 0.08 185 12 0.0104347826086956 1
CACNA2D3-204 CACNA2D3 Q8IZS8 Voltage-dependent calcium channel subunit alpha-2/delta-3 chr3 GO:0070588 Not Cancer Driver No 209 0.1915673693858845 38 7 0.0064161319890009 0
CACNA2D4-202 CACNA2D4 Q7Z3S7 Voltage-dependent calcium channel subunit alpha-2/delta-4 chr12 GO:0070588 Not Cancer Driver No 169 0.148636763412489 70 6 0.0052770448548812 0
CACNB1-202 CACNB1 Q02641 Voltage-dependent L-type calcium channel subunit beta-1 chr17 GO:0070588 Not Cancer Driver No 60 0.1003344481605351 398 35 0.0585284280936454 0
CACNB2-202 CACNB2 Q08289 Voltage-dependent L-type calcium channel subunit beta-2 chr10 GO:0070588 Not Cancer Driver No 116 0.1757575757575757 481 91 0.1378787878787878 0
CACNB4-210 CACNB4 O00305 Voltage-dependent L-type calcium channel subunit beta-4 chr2 GO:0070588 Not Cancer Driver No 59 0.1134615384615384 295 38 0.073076923076923 1
CACNG1-201 CACNG1 Q06432 Voltage-dependent calcium channel gamma-1 subunit chr17 GO:0070588 Not Cancer Driver No 27 0.1216216216216216 0 0 0.0 0
CACNG2-201 CACNG2 Q9Y698 Voltage-dependent calcium channel gamma-2 subunit chr22 GO:0070588 Not Cancer Driver No 50 0.1547987616099071 92 15 0.0464396284829721 1
CACNG3-201 CACNG3 O60359 Voltage-dependent calcium channel gamma-3 subunit chr16 GO:0070588 Not Cancer Driver No 107 0.3396825396825397 69 39 0.1238095238095238 0
CACNG4-201 CACNG4 Q9UBN1 Voltage-dependent calcium channel gamma-4 subunit chr17 GO:0070588 Not Cancer Driver No 45 0.1376146788990825 72 15 0.0458715596330275 0
CACNG5-202 CACNG5 Q9UF02 Voltage-dependent calcium channel gamma-5 subunit chr17 GO:0070588 Not Cancer Driver No 57 0.2072727272727272 1 0 0.0 0
CACNG6-201 CACNG6 Q9BXT2 Voltage-dependent calcium channel gamma-6 subunit chr19 GO:0070588 Not Cancer Driver No 45 0.173076923076923 20 2 0.0076923076923076 0
CACNG7-203 CACNG7 P62955 Voltage-dependent calcium channel gamma-7 subunit chr19 GO:0070588 Not Cancer Driver No 81 0.2945454545454545 9 1 0.0036363636363636 0
CACNG8-201 CACNG8 Q8WXS5 Voltage-dependent calcium channel gamma-8 subunit chr19 GO:0070588 Not Cancer Driver No 43 0.1011764705882353 205 12 0.028235294117647 0
CALHM1-201 CALHM1 Q8IU99 Calcium homeostasis modulator protein 1 chr10 GO:0070588 Not Cancer Driver No 35 0.1011560693641618 76 8 0.0231213872832369 0
CATSPER1-201 CATSPER1 Q8NEC5 Cation channel sperm-associated protein 1 chr11 GO:0070588 Not Cancer Driver No 108 0.1384615384615384 423 76 0.0974358974358974 0
CATSPER2-203 CATSPER2 Q96P56 Cation channel sperm-associated protein 2 chr15 GO:0070588 Not Cancer Driver No 51 0.0962264150943396 103 5 0.0094339622641509 0
CATSPER3-201 CATSPER3 Q86XQ3 Cation channel sperm-associated protein 3 chr5 GO:0070588 Not Cancer Driver No 47 0.1180904522613065 19 1 0.0025125628140703 0
CATSPER4-202 CATSPER4 Q7RTX7 Cation channel sperm-associated protein 4 chr1 GO:0070588 Not Cancer Driver No 57 0.1207627118644067 100 12 0.0254237288135593 0
CHRNA10-201 CHRNA10 Q9GZZ6 Neuronal acetylcholine receptor subunit alpha-10 chr11 GO:0070588 Not Cancer Driver No 41 0.0911111111111111 35 3 0.0066666666666666 0
CHRNA7-201 CHRNA7 P36544 Neuronal acetylcholine receptor subunit alpha-7 chr15 GO:0070588 Not Cancer Driver No 50 0.099601593625498 18 3 0.0059760956175298 0
CHRNA9-201 CHRNA9 Q9UGM1 Neuronal acetylcholine receptor subunit alpha-9 chr4 GO:0070588 Not Cancer Driver No 55 0.1148225469728601 23 3 0.0062630480167014 0
CUL5-201 CUL5 Q93034 Cullin-5 chr11 GO:0070588 Not Cancer Driver No 69 0.0884615384615384 5 1 0.0012820512820512 0
EDN1-201 EDN1 P05305 Endothelin-1 chr6 GO:0070588 Not Cancer Driver No 27 0.1273584905660377 98 16 0.0754716981132075 3
EDNRA-209 EDNRA P25101 Endothelin-1 receptor chr4 GO:0070588 Not Cancer Driver No 52 0.1217798594847775 21 5 0.0117096018735363 2
EDNRB-207 EDNRB P24530 Endothelin receptor type B chr13 GO:0070588 Not Cancer Driver No 94 0.2126696832579185 56 13 0.0294117647058823 9
FKBP1A-204 FKBP1A P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A chr20 GO:0070588 Not Cancer Driver No 11 0.1018518518518518 39 6 0.0555555555555555 0
GAS6-201 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0070588 Not Cancer Driver No 60 0.0884955752212389 43 3 0.0044247787610619 0
GPM6A-202 GPM6A P51674 Neuronal membrane glycoprotein M6-a chr4 GO:0070588 Not Cancer Driver No 62 0.2230215827338129 15 2 0.0071942446043165 0
GRIN3A-201 GRIN3A Q8TCU5 Glutamate receptor ionotropic, NMDA 3A chr9 GO:0070588 Not Cancer Driver No 252 0.2260089686098654 183 19 0.0170403587443946 0
GRIN3B-201 GRIN3B O60391 Glutamate receptor ionotropic, NMDA 3B chr19 GO:0070588 Not Cancer Driver No 60 0.0575263662511984 307 10 0.009587727708533 0
ITGAV-201 ITGAV P06756 Integrin alpha-V chr2 GO:0070588 Census Yes 100 0.0954198473282442 92 8 0.0076335877862595 0
KCNJ8-201 KCNJ8 Q15842 ATP-sensitive inward rectifier potassium channel 8 chr12 GO:0070588 Not Cancer Driver No 78 0.1839622641509433 69 17 0.0400943396226415 1
MCOLN1-201 MCOLN1 Q9GZU1 Mucolipin-1 chr19 GO:0070588 Not Cancer Driver No 55 0.0948275862068965 63 12 0.0206896551724137 7
MCOLN2-202 MCOLN2 Q8IZK6 Mucolipin-2 chr1 GO:0070588 Not Cancer Driver No 65 0.1148409893992932 0 0 0.0 0
MCOLN3-203 MCOLN3 Q8TDD5 Mucolipin-3 chr1 GO:0070588 Not Cancer Driver No 70 0.1265822784810126 9 1 0.0018083182640144 0
NALCN-201 NALCN Q8IZF0 Sodium leak channel NALCN chr13 GO:0070588 Not Cancer Driver No 399 0.2295742232451093 260 62 0.0356731875719217 11
NCS1-201 NCS1 P62166 Neuronal calcium sensor 1 chr9 GO:0070588 Not Cancer Driver No 15 0.0789473684210526 26 0 0.0 0
OPRM1-202 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0070588 Not Cancer Driver No 71 0.1775 59 17 0.0425 0
ORAI1-202 ORAI1 Q96D31 Calcium release-activated calcium channel protein 1 chr12 GO:0070588 Not Cancer Driver No 19 0.0631229235880398 101 6 0.0199335548172757 5
ORAI2-207 ORAI2 Q96SN7 Protein orai-2 chr7 GO:0070588 Not Cancer Driver No 27 0.1062992125984252 23 3 0.0118110236220472 0
ORAI3-201 ORAI3 Q9BRQ5 Protein orai-3 chr16 GO:0070588 Not Cancer Driver No 21 0.0711864406779661 93 8 0.0271186440677966 0
P2RX1-201 P2RX1 P51575 P2X purinoceptor 1 chr17 GO:0070588 Not Cancer Driver No 42 0.1052631578947368 14 0 0.0 0
P2RX2-208 P2RX2 Q9UBL9 P2X purinoceptor 2 chr12 GO:0070588 Not Cancer Driver No 53 0.1125265392781316 105 10 0.0212314225053078 2
P2RX3-201 P2RX3 P56373 P2X purinoceptor 3 chr11 GO:0070588 Not Cancer Driver No 63 0.1586901763224181 15 3 0.0075566750629722 0
P2RX4-202 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0070588 Not Cancer Driver No 20 0.0515463917525773 0 0 0.0 0
P2RX5-201 P2RX5 Q93086 P2X purinoceptor 5 chr17 GO:0070588 Not Cancer Driver No 41 0.0971563981042654 73 10 0.0236966824644549 0
P2RX5-TAX1BP3-201 P2RX5 Q93086 P2X purinoceptor 5 chr17 GO:0070588 Not Cancer Driver No 41 0.0949074074074074 84 11 0.0254629629629629 0
P2RX6-202 P2RX6 O15547 P2X purinoceptor 6 chr22 GO:0070588 Not Cancer Driver No 22 0.0498866213151927 43 1 0.0022675736961451 0
P2RX7-202 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0070588 Not Cancer Driver No 37 0.0621848739495798 16 1 0.0016806722689075 0
PANX1-201 PANX1 Q96RD7 Pannexin-1 chr11 GO:0070588 Not Cancer Driver No 40 0.0938967136150234 45 5 0.0117370892018779 2
PKD1-201 PKD1 P98161 Polycystin-1 chr16 GO:0070588 Not Cancer Driver No 299 0.0694864048338368 695 50 0.0116198001394376 91
PKD1L1-201 PKD1L1 Q8TDX9 Polycystin-1-like protein 1 chr7 GO:0070588 Not Cancer Driver No 385 0.1351351351351351 527 79 0.0277290277290277 1
PKD1L3-201 PKD1L3 Q7Z443 Polycystin-1-like protein 3 chr16 GO:0070588 Not Cancer Driver No 0 0.0 148 0 0.0 0
PKD2-201 PKD2 Q13563 Polycystin-2 chr4 GO:0070588 Not Cancer Driver No 88 0.0909090909090909 376 30 0.03099173553719 9
PKD2L1-201 PKD2L1 Q9P0L9 Polycystin-2-like protein 1 chr10 GO:0070588 Not Cancer Driver No 98 0.1217391304347826 182 22 0.0273291925465838 0
PKD2L2-206 PKD2L2 Q9NZM6 Polycystin-2-like protein 2 chr5 GO:0070588 Not Cancer Driver No 54 0.0865384615384615 25 1 0.0016025641025641 0
PKDREJ-201 PKDREJ Q9NTG1 Polycystin family receptor for egg jelly chr22 GO:0070588 Not Cancer Driver No 201 0.0892143808255659 196 26 0.0115401686640035 0
PSEN1-201 PSEN1 P49768 Presenilin-1 chr14 GO:0070588 Not Cancer Driver No 43 0.0920770877944325 134 18 0.038543897216274 69
RYR3-212 RYR3 Q15413 Ryanodine receptor 3 chr15 GO:0070588 Not Cancer Driver No 806 0.1655030800821355 654 116 0.0238193018480492 0
SEC61A1-201 SEC61A1 P61619 Protein transport protein Sec61 subunit alpha isoform 1 chr3 GO:0070588 Not Cancer Driver No 39 0.0819327731092437 0 0 0.0 3
SLC24A1-201 SLC24A1 O60721 Sodium/potassium/calcium exchanger 1 chr15 GO:0070588 Not Cancer Driver No 46 0.0418562329390354 595 26 0.0236578707916287 0
SLC24A2-202 SLC24A2 Q9UI40 Sodium/potassium/calcium exchanger 2 chr9 GO:0070588 Not Cancer Driver No 97 0.1467473524962178 145 24 0.0363086232980332 0
SLC24A3-201 SLC24A3 Q9HC58 Sodium/potassium/calcium exchanger 3 chr20 GO:0070588 Not Cancer Driver No 92 0.1428571428571428 120 37 0.0574534161490683 0
SLC24A4-205 SLC24A4 Q8NFF2 Sodium/potassium/calcium exchanger 4 chr14 GO:0070588 Not Cancer Driver No 107 0.1720257234726688 86 12 0.0192926045016077 2
SLC24A5-201 SLC24A5 Q71RS6 Sodium/potassium/calcium exchanger 5 chr15 GO:0070588 Not Cancer Driver No 51 0.102 7 1 0.002 0
SLC25A25-201 SLC25A25 Q6KCM7 Mitochondrial adenyl nucleotide antiporter SLC25A25 chr9 GO:0070588 Not Cancer Driver No 25 0.0533049040511727 5 1 0.0021321961620469 0
SLC8A1-201 SLC8A1 P32418 Sodium/calcium exchanger 1 chr2 GO:0070588 Not Cancer Driver No 251 0.2579650565262076 158 40 0.0411099691675231 0
SLC8A2-201 SLC8A2 Q9UPR5 Sodium/calcium exchanger 2 chr19 GO:0070588 Not Cancer Driver No 104 0.1129207383279044 143 19 0.020629750271444 0
SLC8A3-203 SLC8A3 P57103 Sodium/calcium exchanger 3 chr14 GO:0070588 Not Cancer Driver No 222 0.2394822006472491 154 31 0.0334412081984897 0
STIM2-204 STIM2 Q9P246 Stromal interaction molecule 2 chr4 GO:0070588 Not Cancer Driver No 57 0.0764075067024128 389 31 0.0415549597855227 0
TMC1-201 TMC1 Q8TDI8 Transmembrane channel-like protein 1 chr9 GO:0070588 Not Cancer Driver No 80 0.1052631578947368 99 9 0.0118421052631578 2
TMC2-201 TMC2 Q8TDI7 Transmembrane channel-like protein 2 chr20 GO:0070588 Not Cancer Driver No 137 0.15121412803532 296 32 0.0353200883002207 0
TMCO1-207 TMCO1 Q9UM00 Calcium load-activated calcium channel chr1 GO:0070588 Not Cancer Driver No 22 0.0920502092050209 49 2 0.00836820083682 0
TMEM165-201 TMEM165 Q9HC07 Transmembrane protein 165 chr4 GO:0070588 Not Cancer Driver No 18 0.0555555555555555 76 4 0.0123456790123456 2
TMEM37-201 TMEM37 Q8WXS4 Voltage-dependent calcium channel gamma-like subunit chr2 GO:0070588 Not Cancer Driver No 26 0.1368421052631579 0 0 0.0 0
TPCN1-201 TPCN1 Q9ULQ1 Two pore channel protein 1 chr12 GO:0070588 Not Cancer Driver No 83 0.1017156862745098 99 8 0.0098039215686274 0
TRPA1-201 TRPA1 O75762 Transient receptor potential cation channel subfamily A member 1 chr8 GO:0070588 Not Cancer Driver No 243 0.2171581769436997 62 10 0.0089365504915102 1
TRPC1-203 TRPC1 P48995 Short transient receptor potential channel 1 chr3 GO:0070588 Not Cancer Driver No 104 0.1311475409836065 53 8 0.0100882723833543 0
TRPC3-202 TRPC3 Q13507 Short transient receptor potential channel 3 chr4 GO:0070588 Not Cancer Driver No 160 0.1737242128121607 137 16 0.017372421281216 1
TRPC4-206 TRPC4 Q9UBN4 Short transient receptor potential channel 4 chr13 GO:0070588 Not Cancer Driver No 226 0.2313203684749232 196 42 0.0429887410440122 0
TRPC4AP-201 TRPC4AP Q8TEL6 Short transient receptor potential channel 4-associated protein chr20 GO:0070588 Not Cancer Driver No 64 0.0803011292346298 70 3 0.0037641154328732 0
TRPC5-201 TRPC5 Q9UL62 Short transient receptor potential channel 5 chrX GO:0070588 Not Cancer Driver No 195 0.2004110996916752 148 23 0.0236382322713257 0
TRPC6-201 TRPC6 Q9Y210 Short transient receptor potential channel 6 chr11 GO:0070588 Not Cancer Driver No 158 0.1697099892588614 166 36 0.0386680988184747 9
TRPC7-206 TRPC7 Q9HCX4 Short transient receptor potential channel 7 chr5 GO:0070588 Not Cancer Driver No 190 0.2204176334106728 107 33 0.0382830626450116 0
TRPM1-202 TRPM1 Q7Z4N2 Transient receptor potential cation channel subfamily M member 1 chr15 GO:0070588 Not Cancer Driver No 184 0.114784778540237 516 51 0.0318153462258265 12
TRPM2-203 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0070588 Not Cancer Driver No 224 0.1490352628077179 267 37 0.0246174318030605 0
TRPM3-218 TRPM3 Q9HCF6 Transient receptor potential cation channel subfamily M member 3 chr9 GO:0070588 Not Cancer Driver No 235 0.1367073880162885 486 64 0.0372309482257126 3
TRPM4-201 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0070588 Not Cancer Driver No 124 0.1021416803953871 149 17 0.0140032948929159 12
TRPM5-204 TRPM5 Q9NZQ8 Transient receptor potential cation channel subfamily M member 5 chr11 GO:0070588 Not Cancer Driver No 98 0.0841201716738197 186 14 0.0120171673819742 0
TRPM6-202 TRPM6 Q9BX84 Transient receptor potential cation channel subfamily M member 6 chr9 GO:0070588 Not Cancer Driver No 303 0.1498516320474777 461 69 0.0341246290801186 6
TRPM7-210 TRPM7 Q96QT4 Transient receptor potential cation channel subfamily M member 7 chr15 GO:0070588 Not Cancer Driver No 133 0.071313672922252 456 37 0.0198391420911528 1
TRPM8-201 TRPM8 Q7Z2W7 Transient receptor potential cation channel subfamily M member 8 chr2 GO:0070588 Not Cancer Driver No 148 0.1340579710144927 45 9 0.0081521739130434 0
TRPV1-207 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0070588 Not Cancer Driver No 62 0.0738974970202622 157 15 0.0178784266984505 0
TRPV2-201 TRPV2 Q9Y5S1 Transient receptor potential cation channel subfamily V member 2 chr17 GO:0070588 Not Cancer Driver No 82 0.1073298429319371 179 20 0.0261780104712041 0
TRPV3-209 TRPV3 Q8NET8 Transient receptor potential cation channel subfamily V member 3 chr17 GO:0070588 Not Cancer Driver No 94 0.1189873417721519 177 27 0.0341772151898734 3
TRPV4-201 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0070588 Not Cancer Driver No 109 0.1251435132032147 232 30 0.0344431687715269 38
TRPV5-201 TRPV5 Q9NQA5 Transient receptor potential cation channel subfamily V member 5 chr7 GO:0070588 Not Cancer Driver No 152 0.2085048010973937 69 11 0.0150891632373113 0
TRPV6-201 TRPV6 Q9H1D0 Transient receptor potential cation channel subfamily V member 6 chr7 GO:0070588 Not Cancer Driver No 139 0.1816993464052287 77 10 0.0130718954248366 6