Total number of protein in "GO:0071260" GO term: 74
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ANKRD1-201 | ANKRD1 | Q15327 | Ankyrin repeat domain-containing protein 1 | chr10 | GO:0071260 | Not Cancer Driver | No | 30 | 0.0940438871473354 | 83 | 7 | 0.0219435736677116 | 0 |
| AQP1-201 | AQP1 | P29972 | Aquaporin-1 | chr7 | GO:0071260 | Not Cancer Driver | No | 30 | 0.1115241635687732 | 4 | 0 | 0.0 | 0 |
| ATP1A2-201 | ATP1A2 | P50993 | Sodium/potassium-transporting ATPase subunit alpha-2 | chr1 | GO:0071260 | Not Cancer Driver | No | 162 | 0.1588235294117647 | 162 | 21 | 0.0205882352941176 | 14 |
| BAD-201 | BAD | Q92934 | Bcl2-associated agonist of cell death | chr11 | GO:0071260 | Not Cancer Driver | No | 10 | 0.0595238095238095 | 165 | 10 | 0.0595238095238095 | 0 |
| BAG3-201 | BAG3 | O95817 | BAG family molecular chaperone regulator 3 | chr10 | GO:0071260 | Not Cancer Driver | No | 30 | 0.0521739130434782 | 572 | 30 | 0.0521739130434782 | 7 |
| BAK1-201 | BAK1 | Q16611 | Bcl-2 homologous antagonist/killer | chr6 | GO:0071260 | Not Cancer Driver | No | 25 | 0.1184834123222748 | 58 | 5 | 0.0236966824644549 | 0 |
| BCL10-202 | BCL10 | O95999 | B-cell lymphoma/leukemia 10 | chr1 | GO:0071260 | Census, Compendium | Yes | 20 | 0.0858369098712446 | 153 | 14 | 0.0600858369098712 | 0 |
| BMP6-201 | BMP6 | P22004 | Bone morphogenetic protein 6 | chr6 | GO:0071260 | Not Cancer Driver | No | 79 | 0.1539961013645224 | 228 | 41 | 0.0799220272904483 | 6 |
| BNIP3-201 | BNIP3 | Q12983 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 | chr10 | GO:0071260 | Not Cancer Driver | No | 16 | 0.0824742268041237 | 131 | 11 | 0.056701030927835 | 0 |
| CASP1-212 | CASP1 | P29466 | Caspase-1 | chr11 | GO:0071260 | Not Cancer Driver | No | 54 | 0.1336633663366336 | 88 | 12 | 0.0297029702970297 | 0 |
| CASP2-201 | CASP2 | P42575 | Caspase-2 | chr7 | GO:0071260 | Not Cancer Driver | No | 49 | 0.1084070796460177 | 42 | 11 | 0.0243362831858407 | 0 |
| CASP5-201 | CASP5 | P51878 | Caspase-5 | chr11 | GO:0071260 | Not Cancer Driver | No | 76 | 0.1751152073732718 | 61 | 13 | 0.0299539170506912 | 0 |
| CASP8-218 | CASP8 | Q14790 | Caspase-8 | chr2 | GO:0071260 | Census, Compendium | Yes | 116 | 0.2421711899791231 | 106 | 11 | 0.022964509394572 | 1 |
| CASP8AP2-205 | CASP8AP2 | Q9UKL3 | CASP8-associated protein 2 | chr6 | GO:0071260 | Not Cancer Driver | No | 0 | 0.0 | 1508 | 0 | 0.0 | 0 |
| CD40-202 | CD40 | P25942 | Tumor necrosis factor receptor superfamily member 5 | chr20 | GO:0071260 | Not Cancer Driver | No | 32 | 0.1155234657039711 | 57 | 6 | 0.0216606498194945 | 2 |
| CHEK1-204 | CHEK1 | O14757 | Serine/threonine-protein kinase Chk1 | chr11 | GO:0071260 | Not Cancer Driver | No | 42 | 0.088235294117647 | 86 | 13 | 0.0273109243697479 | 0 |
| CNN2-201 | CNN2 | Q99439 | Calponin-2 | chr19 | GO:0071260 | Not Cancer Driver | No | 26 | 0.0841423948220064 | 164 | 19 | 0.0614886731391585 | 0 |
| COL1A1-201 | COL1A1 | P02452 | Collagen alpha-1(I) chain | chr17 | GO:0071260 | Census, Compendium | Yes | 36 | 0.0245901639344262 | 1213 | 10 | 0.0068306010928961 | 140 |
| CRADD-201 | CRADD | P78560 | Death domain-containing protein CRADD | chr12 | GO:0071260 | Not Cancer Driver | No | 30 | 0.1507537688442211 | 45 | 4 | 0.0201005025125628 | 1 |
| DAG1-201 | DAG1 | Q14118 | Dystroglycan 1 | chr3 | GO:0071260 | Not Cancer Driver | No | 71 | 0.0793296089385474 | 486 | 43 | 0.0480446927374301 | 4 |
| EGFR-201 | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:0071260 | Census, Compendium | Yes | 346 | 0.2859504132231405 | 223 | 30 | 0.024793388429752 | 1 |
| ENG-202 | ENG | P17813 | Endoglin | chr9 | GO:0071260 | Not Cancer Driver | No | 47 | 0.0714285714285714 | 114 | 11 | 0.0167173252279635 | 29 |
| ENST00000560629 | ITGB3 | P05106 | Integrin beta-3 | chr17 | GO:0071260 | Not Cancer Driver | No | 92 | 0.1168996188055908 | 68 | 6 | 0.0076238881829733 | 27 |
| F11R-202 | F11R | Q9Y624 | Junctional adhesion molecule A | chr1 | GO:0071260 | Not Cancer Driver | No | 42 | 0.1404682274247491 | 72 | 12 | 0.040133779264214 | 0 |
| FADD-201 | FADD | Q13158 | FAS-associated death domain protein | chr11 | GO:0071260 | Not Cancer Driver | No | 24 | 0.1153846153846153 | 45 | 9 | 0.0432692307692307 | 1 |
| FAS-221 | FAS | P25445 | Tumor necrosis factor receptor superfamily member 6 | chr10 | GO:0071260 | Census, Compendium | Yes | 35 | 0.1044776119402985 | 63 | 15 | 0.044776119402985 | 16 |
| FGF2-201 | FGF2 | P09038 | Fibroblast growth factor 2 | chr4 | GO:0071260 | Not Cancer Driver | No | 17 | 0.0590277777777777 | 183 | 5 | 0.0173611111111111 | 0 |
| GADD45A-202 | GADD45A | P24522 | Growth arrest and DNA damage-inducible protein GADD45 alpha | chr1 | GO:0071260 | Not Cancer Driver | No | 8 | 0.0484848484848484 | 40 | 4 | 0.0242424242424242 | 0 |
| GCLC-214 | GCLC | P48506 | Glutamate--cysteine ligase catalytic subunit | chr6 | GO:0071260 | Not Cancer Driver | No | 55 | 0.086342229199372 | 167 | 15 | 0.0235478806907378 | 3 |
| HABP4-201 | HABP4 | Q5JVS0 | Intracellular hyaluronan-binding protein 4 | chr9 | GO:0071260 | Not Cancer Driver | No | 21 | 0.0508474576271186 | 415 | 21 | 0.0508474576271186 | 0 |
| IGF1R-217 | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:0071260 | Not Cancer Driver | No | 143 | 0.1046086320409656 | 265 | 30 | 0.021945866861741 | 6 |
| IL13-201 | IL13 | P35225 | Interleukin-13 | chr5 | GO:0071260 | Not Cancer Driver | No | 12 | 0.0821917808219178 | 0 | 0 | 0.0 | 0 |
| IL1B-201 | IL1B | P01584 | Interleukin-1 beta | chr2 | GO:0071260 | Not Cancer Driver | No | 32 | 0.1189591078066914 | 16 | 2 | 0.0074349442379182 | 0 |
| IL33-206 | IL33 | O95760 | Interleukin-33 | chr9 | GO:0071260 | Not Cancer Driver | No | 31 | 0.1148148148148148 | 47 | 5 | 0.0185185185185185 | 0 |
| IRF1-201 | IRF1 | P10914 | Interferon regulatory factor 1 | chr5 | GO:0071260 | Compendium | Yes | 38 | 0.1169230769230769 | 228 | 21 | 0.0646153846153846 | 2 |
| ITGA2-201 | ITGA2 | P17301 | Integrin alpha-2 | chr5 | GO:0071260 | Not Cancer Driver | No | 116 | 0.0982218458933107 | 26 | 0 | 0.0 | 0 |
| ITGB3-201 | ITGB3 | P05106 | Integrin beta-3 | chr17 | GO:0071260 | Not Cancer Driver | No | 92 | 0.116751269035533 | 68 | 5 | 0.0063451776649746 | 28 |
| KCNJ2-201 | KCNJ2 | P63252 | Inward rectifier potassium channel 2 | chr17 | GO:0071260 | Not Cancer Driver | No | 85 | 0.1990632318501171 | 49 | 7 | 0.0163934426229508 | 12 |
| KCNK4-202 | KCNK4 | Q9NYG8 | Potassium channel subfamily K member 4 | chr11 | GO:0071260 | Not Cancer Driver | No | 25 | 0.0636132315521628 | 142 | 4 | 0.010178117048346 | 2 |
| LTBR-201 | LTBR | P36941 | Tumor necrosis factor receptor superfamily member 3 | chr12 | GO:0071260 | Not Cancer Driver | No | 31 | 0.0712643678160919 | 202 | 16 | 0.0367816091954023 | 0 |
| MAG-202 | MAG | P20916 | Myelin-associated glycoprotein | chr19 | GO:0071260 | Not Cancer Driver | No | 101 | 0.1613418530351437 | 65 | 9 | 0.0143769968051118 | 1 |
| MAP2K4-201 | MAP2K4 | P45985 | Dual specificity mitogen-activated protein kinase kinase 4 | chr17 | GO:0071260 | Census, Compendium | Yes | 72 | 0.1804511278195488 | 137 | 23 | 0.0576441102756892 | 0 |
| MAP3K1-201 | MAP3K1 | Q13233 | Mitogen-activated protein kinase kinase kinase 1 | chr5 | GO:0071260 | Census, Compendium | Yes | 137 | 0.0906084656084656 | 829 | 43 | 0.0284391534391534 | 1 |
| MAP3K14-201 | MAP3K14 | Q99558 | Mitogen-activated protein kinase kinase kinase 14 | chr17 | GO:0071260 | Not Cancer Driver | No | 0 | 0.0 | 543 | 0 | 0.0 | 0 |
| MAP3K2-203 | MAP3K2 | Q9Y2U5 | Mitogen-activated protein kinase kinase kinase 2 | chr2 | GO:0071260 | Not Cancer Driver | No | 53 | 0.08562197092084 | 316 | 35 | 0.0565428109854604 | 0 |
| MAPK3-201 | MAPK3 | P27361 | Mitogen-activated protein kinase 3 | chr16 | GO:0071260 | Not Cancer Driver | No | 32 | 0.0844327176781002 | 49 | 3 | 0.0079155672823219 | 0 |
| MAPK8-206 | MAPK8 | P45983 | Mitogen-activated protein kinase 8 | chr10 | GO:0071260 | Not Cancer Driver | No | 52 | 0.1217798594847775 | 94 | 9 | 0.0210772833723653 | 0 |
| MTPN-201 | MTPN | P58546 | Myotrophin | chr7 | GO:0071260 | Not Cancer Driver | No | 7 | 0.059322033898305 | 11 | 3 | 0.0254237288135593 | 0 |
| MYD88-209 | MYD88 | Q99836 | Myeloid differentiation primary response protein MyD88 | chr3 | GO:0071260 | Census, Compendium | Yes | 29 | 0.0979729729729729 | 47 | 2 | 0.0067567567567567 | 2 |
| NFKB1-205 | NFKB1 | P19838 | Nuclear factor NF-kappa-B p105 subunit | chr4 | GO:0071260 | Not Cancer Driver | No | 62 | 0.0640495867768595 | 345 | 30 | 0.03099173553719 | 0 |
| PDE2A-201 | PDE2A | O00408 | cGMP-dependent 3',5'-cyclic phosphodiesterase | chr11 | GO:0071260 | Not Cancer Driver | No | 82 | 0.0871413390010627 | 99 | 5 | 0.0053134962805526 | 0 |
| PIEZO1-201 | PIEZO1 | Q92508 | Piezo-type mechanosensitive ion channel component 1 | chr16 | GO:0071260 | Not Cancer Driver | No | 66 | 0.0261800872669575 | 475 | 10 | 0.0039666798889329 | 11 |
| PIEZO2-203 | PIEZO2 | Q9H5I5 | Piezo-type mechanosensitive ion channel component 2 | chr18 | GO:0071260 | Not Cancer Driver | No | 129 | 0.046875 | 609 | 11 | 0.0039970930232558 | 7 |
| PLEC-201 | PLEC | Q15149 | Plectin | chr8 | GO:0071260 | Not Cancer Driver | No | 336 | 0.0717335610589239 | 2138 | 125 | 0.0266865926558497 | 2 |
| PTGER4-201 | PTGER4 | P35408 | Prostaglandin E2 receptor EP4 subtype | chr5 | GO:0071260 | Not Cancer Driver | No | 54 | 0.110655737704918 | 118 | 11 | 0.0225409836065573 | 0 |
| PTGS2-201 | PTGS2 | P35354 | Prostaglandin G/H synthase 2 | chr1 | GO:0071260 | Not Cancer Driver | No | 68 | 0.1125827814569536 | 31 | 4 | 0.0066225165562913 | 0 |
| SCX-201 | SCX | Q7RTU7 | Basic helix-loop-helix transcription factor scleraxis | chr8 | GO:0071260 | Not Cancer Driver | No | 0 | 0.0 | 191 | 0 | 0.0 | 0 |
| SLC2A1-203 | SLC2A1 | P11166 | Solute carrier family 2, facilitated glucose transporter member 1 | chr1 | GO:0071260 | Not Cancer Driver | No | 43 | 0.0873983739837398 | 13 | 2 | 0.0040650406504065 | 44 |
| SLC38A2-201 | SLC38A2 | Q96QD8 | Sodium-coupled neutral amino acid symporter 2 | chr12 | GO:0071260 | Not Cancer Driver | No | 42 | 0.0830039525691699 | 9 | 1 | 0.0019762845849802 | 0 |
| SLC9A1-201 | SLC9A1 | P19634 | Sodium/hydrogen exchanger 1 | chr1 | GO:0071260 | Not Cancer Driver | No | 57 | 0.0699386503067484 | 252 | 17 | 0.0208588957055214 | 1 |
| SOX9-201 | SOX9 | P48436 | Transcription factor SOX-9 | chr17 | GO:0071260 | Compendium | Yes | 69 | 0.1355599214145383 | 497 | 66 | 0.1296660117878192 | 13 |
| TLR3-201 | TLR3 | O15455 | Toll-like receptor 3 | chr4 | GO:0071260 | Not Cancer Driver | No | 89 | 0.0984513274336283 | 0 | 0 | 0.0 | 1 |
| TLR4-201 | TLR4 | O00206 | Toll-like receptor 4 | chr9 | GO:0071260 | Not Cancer Driver | No | 253 | 0.301549463647199 | 0 | 0 | 0.0 | 0 |
| TLR5-206 | TLR5 | O60602 | Toll-like receptor 5 | chr1 | GO:0071260 | Not Cancer Driver | No | 103 | 0.12004662004662 | 18 | 1 | 0.0011655011655011 | 0 |
| TLR7-201 | TLR7 | Q9NYK1 | Toll-like receptor 7 | chrX | GO:0071260 | Not Cancer Driver | No | 129 | 0.1229742612011439 | 14 | 1 | 0.0009532888465204 | 4 |
| TLR8-201 | TLR8 | Q9NR97 | Toll-like receptor 8 | chrX | GO:0071260 | Not Cancer Driver | No | 125 | 0.1200768491834774 | 30 | 3 | 0.0028818443804034 | 3 |
| TMEM150C-201 | TMEM150C | B9EJG8 | Transmembrane protein 150C | chr4 | GO:0071260 | Not Cancer Driver | No | 25 | 0.1004016064257028 | 0 | 0 | 0.0 | 0 |
| TMEM87A-202 | TMEM87A | Q8NBN3 | Transmembrane protein 87A | chr15 | GO:0071260 | Not Cancer Driver | No | 46 | 0.0828828828828828 | 71 | 6 | 0.0108108108108108 | 0 |
| TNFRSF10A-201 | TNFRSF10A | O00220 | Tumor necrosis factor receptor superfamily member 10A | chr8 | GO:0071260 | Not Cancer Driver | No | 39 | 0.0833333333333333 | 175 | 14 | 0.0299145299145299 | 0 |
| TNFRSF10B-201 | TNFRSF10B | O14763 | Tumor necrosis factor receptor superfamily member 10B | chr8 | GO:0071260 | Not Cancer Driver | No | 36 | 0.0818181818181818 | 192 | 15 | 0.034090909090909 | 0 |
| TNFRSF1A-201 | TNFRSF1A | P19438 | Tumor necrosis factor receptor superfamily member 1A | chr12 | GO:0071260 | Not Cancer Driver | No | 38 | 0.0835164835164835 | 111 | 14 | 0.0307692307692307 | 9 |
| TNFRSF8-201 | TNFRSF8 | P28908 | Tumor necrosis factor receptor superfamily member 8 | chr1 | GO:0071260 | Not Cancer Driver | No | 76 | 0.1277310924369747 | 290 | 29 | 0.0487394957983193 | 0 |
| TNFSF14-203 | TNFSF14 | O43557 | Tumor necrosis factor ligand superfamily member 14 | chr19 | GO:0071260 | Not Cancer Driver | No | 44 | 0.1833333333333333 | 19 | 2 | 0.0083333333333333 | 0 |
| WNT11-201 | WNT11 | O96014 | Protein Wnt-11 | chr11 | GO:0071260 | Not Cancer Driver | No | 37 | 0.1045197740112994 | 59 | 3 | 0.0084745762711864 | 0 |