Total number of protein in "GO:0071333" GO term: 62
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACE-202 | ACE | P12821 | Angiotensin-converting enzyme | chr17 | GO:0071333 | Not Cancer Driver | No | 152 | 0.116385911179173 | 87 | 5 | 0.0038284839203675 | 0 |
| ADCY8-201 | ADCY8 | P40145 | Adenylate cyclase type 8 | chr8 | GO:0071333 | Not Cancer Driver | No | 358 | 0.2861710631494804 | 215 | 31 | 0.0247801758593125 | 0 |
| CASR-205 | CASR | P41180 | Extracellular calcium-sensing receptor | chr3 | GO:0071333 | Not Cancer Driver | No | 234 | 0.2170686456400742 | 189 | 46 | 0.0426716141001855 | 100 |
| CMA1-202 | CMA1 | P23946 | Chymase | chr14 | GO:0071333 | Not Cancer Driver | No | 39 | 0.1578947368421052 | 9 | 1 | 0.0040485829959514 | 0 |
| COL1A1-201 | COL1A1 | P02452 | Collagen alpha-1(I) chain | chr17 | GO:0071333 | Census, Compendium | Yes | 36 | 0.0245901639344262 | 1213 | 10 | 0.0068306010928961 | 140 |
| CPB2-201 | CPB2 | Q96IY4 | Carboxypeptidase B2 | chr13 | GO:0071333 | Not Cancer Driver | No | 42 | 0.0992907801418439 | 2 | 0 | 0.0 | 0 |
| CYP7A1-201 | CYP7A1 | P22680 | Cytochrome P450 7A1 | chr8 | GO:0071333 | Not Cancer Driver | No | 71 | 0.1408730158730158 | 48 | 4 | 0.0079365079365079 | 0 |
| ERN1-201 | ERN1 | O75460 | Serine/threonine-protein kinase/endoribonuclease IRE1 | chr17 | GO:0071333 | Not Cancer Driver | No | 91 | 0.0931422722620266 | 251 | 17 | 0.0174002047082906 | 0 |
| FGF21-202 | FGF21 | Q9NSA1 | Fibroblast growth factor 21 | chr19 | GO:0071333 | Not Cancer Driver | No | 27 | 0.1291866028708134 | 110 | 20 | 0.0956937799043062 | 0 |
| FOXO3-202 | FOXO3 | O43524 | Forkhead box protein O3 | chr6 | GO:0071333 | Census, Compendium | Yes | 54 | 0.0802377414561664 | 597 | 50 | 0.0742942050520059 | 0 |
| GAS6-201 | GAS6 | Q14393 | Growth arrest-specific protein 6 | chr13 | GO:0071333 | Not Cancer Driver | No | 60 | 0.0884955752212389 | 43 | 3 | 0.0044247787610619 | 0 |
| GATA4-201 | GATA4 | P43694 | Transcription factor GATA-4 | chr8 | GO:0071333 | Not Cancer Driver | No | 34 | 0.0769230769230769 | 297 | 23 | 0.0520361990950226 | 21 |
| GCLC-214 | GCLC | P48506 | Glutamate--cysteine ligase catalytic subunit | chr6 | GO:0071333 | Not Cancer Driver | No | 55 | 0.086342229199372 | 167 | 15 | 0.0235478806907378 | 3 |
| GCLM-201 | GCLM | P48507 | Glutamate--cysteine ligase regulatory subunit | chr1 | GO:0071333 | Not Cancer Driver | No | 21 | 0.0766423357664233 | 31 | 3 | 0.010948905109489 | 0 |
| GJB6-213 | GJB6 | O95452 | Gap junction beta-6 protein | chr13 | GO:0071333 | Not Cancer Driver | No | 26 | 0.0996168582375478 | 12 | 4 | 0.0153256704980842 | 3 |
| GPER1-202 | GPER1 | Q99527 | G-protein coupled estrogen receptor 1 | chr7 | GO:0071333 | Not Cancer Driver | No | 47 | 0.1253333333333333 | 13 | 4 | 0.0106666666666666 | 0 |
| GPX1-202 | GPX1 | P07203 | Glutathione peroxidase 1 | chr3 | GO:0071333 | Not Cancer Driver | No | 22 | 0.1083743842364532 | 12 | 3 | 0.0147783251231527 | 0 |
| ICAM1-201 | ICAM1 | P05362 | Intercellular adhesion molecule 1 | chr19 | GO:0071333 | Not Cancer Driver | No | 52 | 0.0977443609022556 | 253 | 25 | 0.0469924812030075 | 0 |
| IGF1R-217 | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:0071333 | Not Cancer Driver | No | 143 | 0.1046086320409656 | 265 | 30 | 0.021945866861741 | 6 |
| IRS2-201 | IRS2 | Q9Y4H2 | Insulin receptor substrate 2 | chr13 | GO:0071333 | Not Cancer Driver | No | 44 | 0.0328849028400597 | 1117 | 34 | 0.0254110612855007 | 0 |
| KAT5-203 | KAT5 | Q92993 | Histone acetyltransferase KAT5 | chr11 | GO:0071333 | Not Cancer Driver | No | 45 | 0.087719298245614 | 174 | 16 | 0.0311890838206627 | 3 |
| KCNB1-201 | KCNB1 | Q14721 | Potassium voltage-gated channel subfamily B member 1 | chr20 | GO:0071333 | Not Cancer Driver | No | 154 | 0.1794871794871795 | 417 | 82 | 0.0955710955710955 | 6 |
| KCNJ11-201 | KCNJ11 | Q14654 | ATP-sensitive inward rectifier potassium channel 11 | chr11 | GO:0071333 | Not Cancer Driver | No | 34 | 0.0871794871794871 | 20 | 1 | 0.0025641025641025 | 37 |
| LIN28A-202 | LIN28A | Q9H9Z2 | Protein lin-28 homolog A | chr1 | GO:0071333 | Not Cancer Driver | No | 30 | 0.1435406698564593 | 86 | 11 | 0.0526315789473684 | 0 |
| NCF1-201 | NCF1 | P14598 | Neutrophil cytosol factor 1 | chr7 | GO:0071333 | Not Cancer Driver | No | 31 | 0.0794871794871794 | 181 | 11 | 0.0282051282051282 | 1 |
| NEUROD1-201 | NEUROD1 | Q13562 | Neurogenic differentiation factor 1 | chr2 | GO:0071333 | Not Cancer Driver | No | 68 | 0.1910112359550561 | 203 | 42 | 0.1179775280898876 | 2 |
| NME2-205 | NME2 | P22392 | Nucleoside diphosphate kinase B | chr17 | GO:0071333 | Not Cancer Driver | No | 9 | 0.0592105263157894 | 11 | 0 | 0.0 | 0 |
| NOX4-201 | NOX4 | Q9NPH5 | NADPH oxidase 4 | chr11 | GO:0071333 | Not Cancer Driver | No | 101 | 0.1747404844290657 | 0 | 0 | 0.0 | 0 |
| NPTX1-201 | NPTX1 | Q15818 | Neuronal pentraxin-1 | chr17 | GO:0071333 | Not Cancer Driver | No | 49 | 0.1134259259259259 | 187 | 17 | 0.0393518518518518 | 2 |
| OGT-202 | OGT | O15294 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | chrX | GO:0071333 | Not Cancer Driver | No | 111 | 0.1061185468451242 | 90 | 9 | 0.008604206500956 | 2 |
| OPRK1-201 | OPRK1 | P41145 | Kappa-type opioid receptor | chr8 | GO:0071333 | Not Cancer Driver | No | 97 | 0.2552631578947368 | 18 | 5 | 0.0131578947368421 | 0 |
| PAX2-205 | PAX2 | Q02962 | Paired box protein Pax-2 | chr10 | GO:0071333 | Not Cancer Driver | No | 49 | 0.1175059952038369 | 294 | 39 | 0.0935251798561151 | 22 |
| PAX6-203 | PAX6 | P26367 | Paired box protein Pax-6 | chr11 | GO:0071333 | Not Cancer Driver | No | 51 | 0.1208530805687203 | 338 | 37 | 0.0876777251184834 | 35 |
| PCK1-201 | PCK1 | P35558 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | chr20 | GO:0071333 | Not Cancer Driver | No | 112 | 0.180064308681672 | 111 | 24 | 0.0385852090032154 | 1 |
| PCK2-201 | PCK2 | Q16822 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial | chr14 | GO:0071333 | Not Cancer Driver | No | 65 | 0.1015625 | 139 | 9 | 0.0140625 | 0 |
| PIK3CA-201 | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0071333 | Census, Compendium | Yes | 1425 | 1.3342696629213484 | 38 | 9 | 0.0084269662921348 | 44 |
| PPP3CA-203 | PPP3CA | Q08209 | Protein phosphatase 3 catalytic subunit alpha | chr4 | GO:0071333 | Compendium | Yes | 63 | 0.1209213051823416 | 140 | 24 | 0.0460652591170825 | 7 |
| PRKAA1-204 | PRKAA1 | Q13131 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | chr5 | GO:0071333 | Not Cancer Driver | No | 54 | 0.0966010733452593 | 124 | 13 | 0.0232558139534883 | 0 |
| PRKAA2-201 | PRKAA2 | P54646 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | chr1 | GO:0071333 | Not Cancer Driver | No | 90 | 0.1630434782608695 | 98 | 18 | 0.0326086956521739 | 0 |
| PRKACA-201 | PRKACA | P17612 | cAMP-dependent protein kinase catalytic subunit alpha | chr19 | GO:0071333 | Census | Yes | 49 | 0.1396011396011396 | 24 | 0 | 0.0 | 2 |
| RACK1-227 | RACK1 | P63244 | Small ribosomal subunit protein RACK1 | chr5 | GO:0071333 | Not Cancer Driver | No | 27 | 0.085173501577287 | 13 | 0 | 0.0 | 0 |
| RPTOR-201 | RPTOR | Q8N122 | Regulatory-associated protein of mTOR | chr17 | GO:0071333 | Not Cancer Driver | No | 149 | 0.1116104868913857 | 242 | 18 | 0.0134831460674157 | 0 |
| SERPINF1-201 | SERPINF1 | P36955 | Pigment epithelium-derived factor | chr17 | GO:0071333 | Not Cancer Driver | No | 37 | 0.0885167464114832 | 57 | 5 | 0.0119617224880382 | 0 |
| SIN3A-202 | SIN3A | Q96ST3 | Paired amphipathic helix protein Sin3a | chr15 | GO:0071333 | Compendium | Yes | 137 | 0.1076197957580518 | 617 | 60 | 0.0471327572663 | 0 |
| SLC12A6-202 | SLC12A6 | Q9UHW9 | Solute carrier family 12 member 6 | chr15 | GO:0071333 | Not Cancer Driver | No | 123 | 0.1069565217391304 | 281 | 33 | 0.028695652173913 | 5 |
| SLC12A7-201 | SLC12A7 | Q9Y666 | Solute carrier family 12 member 7 | chr5 | GO:0071333 | Not Cancer Driver | No | 126 | 0.1163434903047091 | 202 | 23 | 0.0212373037857802 | 0 |
| SLC29A1-206 | SLC29A1 | Q99808 | Equilibrative nucleoside transporter 1 | chr6 | GO:0071333 | Not Cancer Driver | No | 38 | 0.0833333333333333 | 27 | 3 | 0.006578947368421 | 0 |
| SLC39A14-204 | SLC39A14 | Q15043 | Metal cation symporter ZIP14 | chr8 | GO:0071333 | Not Cancer Driver | No | 27 | 0.0548780487804878 | 42 | 3 | 0.0060975609756097 | 4 |
| SMAD2-201 | SMAD2 | Q15796 | Mothers against decapentaplegic homolog 2 | chr18 | GO:0071333 | Census, Compendium | Yes | 58 | 0.1241970021413276 | 137 | 11 | 0.0235546038543897 | 3 |
| SMAD3-201 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0071333 | Census, Compendium | Yes | 80 | 0.188235294117647 | 113 | 15 | 0.0352941176470588 | 5 |
| SMAD4-201 | SMAD4 | Q13485 | Mothers against decapentaplegic homolog 4 | chr18 | GO:0071333 | Census, Compendium | Yes | 172 | 0.3115942028985507 | 195 | 16 | 0.0289855072463768 | 6 |
| SOX4-201 | SOX4 | Q06945 | Transcription factor SOX-4 | chr6 | GO:0071333 | Not Cancer Driver | No | 25 | 0.0527426160337552 | 402 | 20 | 0.0421940928270042 | 4 |
| SRF-201 | SRF | P11831 | Serum response factor | chr6 | GO:0071333 | Not Cancer Driver | No | 30 | 0.0590551181102362 | 443 | 29 | 0.0570866141732283 | 0 |
| TH-206 | TH | P07101 | Tyrosine 3-monooxygenase | chr11 | GO:0071333 | Not Cancer Driver | No | 48 | 0.0909090909090909 | 151 | 17 | 0.0321969696969696 | 38 |
| TRA2B-204 | TRA2B | P62995 | Transformer-2 protein homolog beta | chr3 | GO:0071333 | Not Cancer Driver | No | 24 | 0.0833333333333333 | 244 | 20 | 0.0694444444444444 | 0 |
| TREM2-202 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:0071333 | Not Cancer Driver | No | 31 | 0.1347826086956521 | 27 | 2 | 0.008695652173913 | 1 |
| TWNK-201 | TWNK | Q96RR1 | Twinkle mtDNA helicase | chr10 | GO:0071333 | Not Cancer Driver | No | 71 | 0.1038011695906432 | 136 | 8 | 0.0116959064327485 | 31 |
| UCP2-211 | UCP2 | P55851 | Dicarboxylate carrier SLC25A8 | chr11 | GO:0071333 | Not Cancer Driver | No | 23 | 0.0744336569579288 | 12 | 4 | 0.0129449838187702 | 0 |
| UNC13B-201 | UNC13B | O14795 | Protein unc-13 homolog B | chr9 | GO:0071333 | Not Cancer Driver | No | 167 | 0.1049654305468259 | 448 | 57 | 0.0358265241986172 | 0 |
| XBP1-201 | XBP1 | P17861 | X-box-binding protein 1 | chr22 | GO:0071333 | Not Cancer Driver | No | 11 | 0.0421455938697318 | 171 | 6 | 0.0229885057471264 | 0 |
| ZBTB20-220 | ZBTB20 | Q9HC78 | Zinc finger and BTB domain-containing protein 20 | chr3 | GO:0071333 | Compendium | Yes | 135 | 0.1821862348178137 | 433 | 66 | 0.0890688259109311 | 4 |
| ZNF236-201 | ZNF236 | Q9UL36 | Zinc finger protein 236 | chr18 | GO:0071333 | Not Cancer Driver | No | 198 | 0.1073170731707317 | 970 | 110 | 0.059620596205962 | 0 |