Total number of protein in "GO:0071363" GO term: 56
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACVR1-207 | ACVR1 | Q04771 | Activin receptor type-1 | chr2 | GO:0071363 | Census, Compendium | Yes | 71 | 0.1394891944990176 | 21 | 8 | 0.0157170923379174 | 6 |
| ACVR1B-201 | ACVR1B | P36896 | Activin receptor type-1B | chr12 | GO:0071363 | Census | Yes | 95 | 0.1881188118811881 | 0 | 0 | 0.0 | 0 |
| ACVR1C-201 | ACVR1C | Q8NER5 | Activin receptor type-1C | chr2 | GO:0071363 | Not Cancer Driver | No | 68 | 0.1379310344827586 | 3 | 1 | 0.0020283975659229 | 0 |
| ACVR2A-201 | ACVR2A | P27037 | Activin receptor type-2A | chr2 | GO:0071363 | Census, Compendium | Yes | 64 | 0.124756335282651 | 56 | 4 | 0.0077972709551656 | 0 |
| ACVR2B-201 | ACVR2B | Q13705 | Activin receptor type-2B | chr3 | GO:0071363 | Not Cancer Driver | No | 55 | 0.107421875 | 70 | 11 | 0.021484375 | 2 |
| ACVRL1-201 | ACVRL1 | P37023 | Serine/threonine-protein kinase receptor R3 | chr12 | GO:0071363 | Not Cancer Driver | No | 80 | 0.1590457256461232 | 60 | 10 | 0.0198807157057654 | 64 |
| AMHR2-201 | AMHR2 | Q16671 | Anti-Muellerian hormone type-2 receptor | chr12 | GO:0071363 | Not Cancer Driver | No | 67 | 0.1169284467713787 | 118 | 9 | 0.0157068062827225 | 8 |
| ANGPT2-201 | ANGPT2 | O15123 | Angiopoietin-2 | chr8 | GO:0071363 | Not Cancer Driver | No | 44 | 0.0887096774193548 | 96 | 7 | 0.0141129032258064 | 1 |
| BGLAP-201 | BGLAP | P02818 | Osteocalcin | chr1 | GO:0071363 | Not Cancer Driver | No | 6 | 0.06 | 21 | 0 | 0.0 | 0 |
| BMPR1A-201 | BMPR1A | P36894 | Bone morphogenetic protein receptor type-1A | chr10 | GO:0071363 | Census, Compendium | Yes | 37 | 0.0695488721804511 | 21 | 0 | 0.0 | 8 |
| BMPR1B-208 | BMPR1B | O00238 | Bone morphogenetic protein receptor type-1B | chr4 | GO:0071363 | Not Cancer Driver | No | 55 | 0.1095617529880478 | 64 | 4 | 0.0079681274900398 | 4 |
| BMPR2-202 | BMPR2 | Q13873 | Bone morphogenetic protein receptor type-2 | chr2 | GO:0071363 | Compendium | Yes | 100 | 0.0963391136801541 | 601 | 49 | 0.0472061657032755 | 17 |
| CAT-201 | CAT | P04040 | Catalase | chr11 | GO:0071363 | Not Cancer Driver | No | 56 | 0.1062618595825427 | 178 | 11 | 0.0208728652751423 | 0 |
| CIB1-201 | CIB1 | Q99828 | Calcium and integrin-binding protein 1 | chr15 | GO:0071363 | Not Cancer Driver | No | 16 | 0.0837696335078534 | 6 | 1 | 0.0052356020942408 | 0 |
| CPNE3-203 | CPNE3 | O75131 | Copine-3 | chr8 | GO:0071363 | Not Cancer Driver | No | 56 | 0.1042830540037244 | 34 | 4 | 0.0074487895716946 | 0 |
| CTNNB1-201 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | GO:0071363 | Census, Compendium | Yes | 363 | 0.4647887323943662 | 288 | 291 | 0.3725992317541613 | 11 |
| DTYMK-201 | DTYMK | P23919 | Thymidylate kinase | chr2 | GO:0071363 | Not Cancer Driver | No | 7 | 0.0330188679245283 | 0 | 0 | 0.0 | 2 |
| EHD4-201 | EHD4 | Q9H223 | EH domain-containing protein 4 | chr15 | GO:0071363 | Not Cancer Driver | No | 39 | 0.0720887245841035 | 98 | 7 | 0.0129390018484288 | 0 |
| EMD-202 | EMD | P50402 | Emerin | chrX | GO:0071363 | Not Cancer Driver | No | 29 | 0.1141732283464567 | 160 | 18 | 0.0708661417322834 | 3 |
| ERBB2-201 | ERBB2 | P04626 | Receptor tyrosine-protein kinase erbB-2 | chr17 | GO:0071363 | Census, Compendium | Yes | 249 | 0.198406374501992 | 315 | 32 | 0.0254980079681274 | 1 |
| FEZ1-201 | FEZ1 | Q99689 | Fasciculation and elongation protein zeta-1 | chr11 | GO:0071363 | Not Cancer Driver | No | 47 | 0.1198979591836734 | 278 | 37 | 0.0943877551020408 | 0 |
| GAS6-201 | GAS6 | Q14393 | Growth arrest-specific protein 6 | chr13 | GO:0071363 | Not Cancer Driver | No | 60 | 0.0884955752212389 | 43 | 3 | 0.0044247787610619 | 0 |
| HTRA2-201 | HTRA2 | O43464 | Serine protease HTRA2, mitochondrial | chr2 | GO:0071363 | Compendium | Yes | 33 | 0.0720524017467248 | 127 | 7 | 0.0152838427947598 | 2 |
| IBSP-201 | IBSP | P21815 | Bone sialoprotein 2 | chr4 | GO:0071363 | Not Cancer Driver | No | 54 | 0.1703470031545741 | 278 | 47 | 0.1482649842271293 | 0 |
| INSR-201 | INSR | P06213 | Insulin receptor | chr19 | GO:0071363 | Not Cancer Driver | No | 139 | 0.1005788712011577 | 282 | 37 | 0.0267727930535455 | 63 |
| KLF4-201 | KLF4 | O43474 | Krueppel-like factor 4 | chr9 | GO:0071363 | Census, Compendium | Yes | 41 | 0.0855949895615866 | 417 | 25 | 0.0521920668058455 | 0 |
| LRP2-205 | LRP2 | P98164 | Low-density lipoprotein receptor-related protein 2 | chr2 | GO:0071363 | Not Cancer Driver | No | 740 | 0.158968850698174 | 209 | 26 | 0.0055853920515574 | 1 |
| LRP8-201 | LRP8 | Q14114 | Low-density lipoprotein receptor-related protein 8 | chr1 | GO:0071363 | Not Cancer Driver | No | 70 | 0.0726895119418483 | 190 | 17 | 0.0176531671858774 | 0 |
| MAP1B-201 | MAP1B | P46821 | Microtubule-associated protein 1B | chr5 | GO:0071363 | Not Cancer Driver | No | 169 | 0.0684764991896272 | 1949 | 166 | 0.0672609400324149 | 0 |
| MAP2K5-201 | MAP2K5 | Q13163 | Dual specificity mitogen-activated protein kinase kinase 5 | chr15 | GO:0071363 | Not Cancer Driver | No | 26 | 0.0580357142857142 | 85 | 6 | 0.0133928571428571 | 0 |
| MAPK7-204 | MAPK7 | Q13164 | Mitogen-activated protein kinase 7 | chr17 | GO:0071363 | Not Cancer Driver | No | 56 | 0.0686274509803921 | 490 | 31 | 0.0379901960784313 | 0 |
| MDM2-224 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | GO:0071363 | Census, Compendium | Yes | 39 | 0.0794297352342158 | 298 | 24 | 0.0488798370672097 | 0 |
| MYOG-201 | MYOG | P15173 | Myogenin | chr1 | GO:0071363 | Not Cancer Driver | No | 31 | 0.1383928571428571 | 133 | 18 | 0.0803571428571428 | 0 |
| NOS1-201 | NOS1 | P29475 | Nitric oxide synthase 1 | chr12 | GO:0071363 | Not Cancer Driver | No | 329 | 0.2294281729428172 | 342 | 84 | 0.0585774058577405 | 0 |
| OPRD1-201 | OPRD1 | P41143 | Delta-type opioid receptor | chr1 | GO:0071363 | Not Cancer Driver | No | 53 | 0.1424731182795699 | 30 | 2 | 0.0053763440860215 | 0 |
| PAX9-201 | PAX9 | P55771 | Paired box protein Pax-9 | chr14 | GO:0071363 | Not Cancer Driver | No | 39 | 0.1143695014662756 | 198 | 25 | 0.0733137829912023 | 1 |
| PDGFB-201 | PDGFB | P01127 | Platelet-derived growth factor subunit B | chr22 | GO:0071363 | Census | Yes | 30 | 0.1244813278008298 | 99 | 16 | 0.0663900414937759 | 2 |
| PLK5-202 | PLK5 | Q496M5 | Inactive serine/threonine-protein kinase PLK5 | chr19 | GO:0071363 | Not Cancer Driver | No | 7 | 0.0208333333333333 | 223 | 3 | 0.0089285714285714 | 0 |
| PPP2R5B-201 | PPP2R5B | Q15173 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform | chr11 | GO:0071363 | Not Cancer Driver | No | 68 | 0.1368209255533199 | 121 | 11 | 0.0221327967806841 | 0 |
| RACK1-227 | RACK1 | P63244 | Small ribosomal subunit protein RACK1 | chr5 | GO:0071363 | Not Cancer Driver | No | 27 | 0.085173501577287 | 13 | 0 | 0.0 | 0 |
| RIPK1-201 | RIPK1 | Q13546 | Receptor-interacting serine/threonine-protein kinase 1 | chr6 | GO:0071363 | Compendium | Yes | 59 | 0.0879284649776453 | 277 | 28 | 0.0417287630402384 | 1 |
| RPS6KB1-201 | RPS6KB1 | P23443 | Ribosomal protein S6 kinase beta-1 | chr17 | GO:0071363 | Not Cancer Driver | No | 36 | 0.0685714285714285 | 226 | 22 | 0.0419047619047619 | 0 |
| SFRP1-201 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | GO:0071363 | Not Cancer Driver | No | 31 | 0.0987261146496815 | 39 | 4 | 0.0127388535031847 | 0 |
| SHC1-202 | SHC1 | P29353 | SHC-transforming protein 1 | chr1 | GO:0071363 | Not Cancer Driver | No | 58 | 0.0994854202401372 | 400 | 41 | 0.0703259005145797 | 0 |
| SLC4A7-201 | SLC4A7 | Q9Y6M7 | Sodium bicarbonate cotransporter 3 | chr3 | GO:0071363 | Not Cancer Driver | No | 105 | 0.086490939044481 | 405 | 37 | 0.0304777594728171 | 0 |
| SPHK1-210 | SPHK1 | Q9NYA1 | Sphingosine kinase 1 | chr17 | GO:0071363 | Not Cancer Driver | No | 29 | 0.0755208333333333 | 25 | 0 | 0.0 | 0 |
| SRD5A1-201 | SRD5A1 | P18405 | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | chr5 | GO:0071363 | Not Cancer Driver | No | 26 | 0.1003861003861003 | 0 | 0 | 0.0 | 0 |
| STAT5B-201 | STAT5B | P51692 | Signal transducer and activator of transcription 5B | chr17 | GO:0071363 | Census, Compendium | Yes | 73 | 0.0927573062261753 | 145 | 17 | 0.0216010165184243 | 5 |
| TGFBR1-202 | TGFBR1 | P36897 | TGF-beta receptor type-1 | chr9 | GO:0071363 | Not Cancer Driver | No | 57 | 0.1133200795228628 | 23 | 3 | 0.0059642147117296 | 13 |
| TGFBR2-201 | TGFBR2 | P37173 | TGF-beta receptor type-2 | chr3 | GO:0071363 | Census, Compendium | Yes | 93 | 0.164021164021164 | 61 | 15 | 0.0264550264550264 | 21 |
| TH-206 | TH | P07101 | Tyrosine 3-monooxygenase | chr11 | GO:0071363 | Not Cancer Driver | No | 48 | 0.0909090909090909 | 151 | 17 | 0.0321969696969696 | 38 |
| THBS1-201 | THBS1 | P07996 | Thrombospondin-1 | chr15 | GO:0071363 | Not Cancer Driver | No | 153 | 0.1307692307692307 | 321 | 50 | 0.0427350427350427 | 0 |
| TNFRSF1B-201 | TNFRSF1B | P20333 | Tumor necrosis factor receptor superfamily member 1B | chr1 | GO:0071363 | Not Cancer Driver | No | 40 | 0.0867678958785249 | 231 | 21 | 0.0455531453362256 | 0 |
| TWF2-201 | TWF2 | Q6IBS0 | Twinfilin-2 | chr3 | GO:0071363 | Not Cancer Driver | No | 28 | 0.0802292263610315 | 59 | 8 | 0.0229226361031518 | 0 |
| TWIST1-201 | TWIST1 | Q15672 | Twist-related protein 1 | chr7 | GO:0071363 | Not Cancer Driver | No | 21 | 0.1039603960396039 | 132 | 9 | 0.0445544554455445 | 6 |
| URI1-202 | URI1 | O94763 | Unconventional prefoldin RPB5 interactor 1 | chr19 | GO:0071363 | Not Cancer Driver | No | 60 | 0.1121495327102803 | 389 | 50 | 0.0934579439252336 | 0 |