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Total number of protein in "GO:0071456" GO term:  121

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACAA2-201 ACAA2 P42765 3-ketoacyl-CoA thiolase, mitochondrial chr18 GO:0071456 Not Cancer Driver No 32 0.0806045340050377 52 1 0.0025188916876574 0
ADAM8-202 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0071456 Not Cancer Driver No 62 0.0752427184466019 232 12 0.0145631067961165 0
ADO-201 ADO Q96SZ5 2-aminoethanethiol dioxygenase chr10 GO:0071456 Not Cancer Driver No 9 0.0333333333333333 180 4 0.0148148148148148 0
AIFM1-201 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX GO:0071456 Not Cancer Driver No 61 0.099510603588907 166 20 0.032626427406199 10
AK4-201 AK4 P27144 Adenylate kinase 4, mitochondrial chr1 GO:0071456 Not Cancer Driver No 16 0.0717488789237668 24 2 0.0089686098654708 0
ANGPT4-201 ANGPT4 Q9Y264 Angiopoietin-4 chr20 GO:0071456 Not Cancer Driver No 87 0.172962226640159 152 31 0.0616302186878727 0
AQP1-201 AQP1 P29972 Aquaporin-1 chr7 GO:0071456 Not Cancer Driver No 30 0.1115241635687732 4 0 0.0 0
AQP3-201 AQP3 Q92482 Aquaporin-3 chr9 GO:0071456 Not Cancer Driver No 25 0.0856164383561643 12 0 0.0 0
ATF4-206 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0071456 Not Cancer Driver No 46 0.131054131054131 261 33 0.094017094017094 0
ATP7A-201 ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0071456 Not Cancer Driver No 152 0.1013333333333333 171 36 0.024 48
BAD-201 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0071456 Not Cancer Driver No 10 0.0595238095238095 165 10 0.0595238095238095 0
BCL2-201 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0071456 Census, Compendium Yes 21 0.0878661087866108 73 5 0.0209205020920502 0
BMP7-201 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0071456 Not Cancer Driver No 68 0.1577726218097447 69 13 0.0301624129930394 0
BNIP3-201 BNIP3 Q12983 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 chr10 GO:0071456 Not Cancer Driver No 16 0.0824742268041237 131 11 0.056701030927835 0
BNIP3L-201 BNIP3L O60238 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like chr8 GO:0071456 Not Cancer Driver No 12 0.0547945205479452 177 10 0.045662100456621 0
BRIP1-201 BRIP1 Q9BX63 Fanconi anemia group J protein chr17 GO:0071456 Census Yes 118 0.0944755804643715 399 41 0.032826261008807 6
CASR-205 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0071456 Not Cancer Driver No 234 0.2170686456400742 189 46 0.0426716141001855 100
CBL-201 CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0071456 Census, Compendium Yes 84 0.0927152317880794 513 44 0.0485651214128035 4
CBS-204 CBS P35520 Cystathionine beta-synthase chr21 GO:0071456 Not Cancer Driver No 0 0.0 160 0 0.0 87
CCNA2-201 CCNA2 P20248 Cyclin-A2 chr4 GO:0071456 Not Cancer Driver No 34 0.0787037037037037 187 14 0.0324074074074074 0
CDKN1B-201 CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0071456 Census, Compendium Yes 14 0.0707070707070707 199 14 0.0707070707070707 0
CFLAR-201 CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0071456 Not Cancer Driver No 31 0.0645833333333333 44 1 0.0020833333333333 0
CITED2-201 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0071456 Not Cancer Driver No 22 0.0814814814814814 232 19 0.0703703703703703 0
CLCA1-202 CLCA1 A8K7I4 Calcium-activated chloride channel regulator 1 chr1 GO:0071456 Not Cancer Driver No 100 0.1094091903719912 213 13 0.0142231947483588 0
CPEB1-219 CPEB1 Q9BZB8 Cytoplasmic polyadenylation element-binding protein 1 chr15 GO:0071456 Not Cancer Driver No 64 0.1088435374149659 221 26 0.0442176870748299 0
CYSLTR1-201 CYSLTR1 Q9Y271 Cysteinyl leukotriene receptor 1 chrX GO:0071456 Not Cancer Driver No 47 0.1394658753709199 8 1 0.0029673590504451 0
DDR2-201 DDR2 Q16832 Discoidin domain-containing receptor 2 chr1 GO:0071456 Census Yes 129 0.1508771929824561 120 25 0.0292397660818713 7
DNMT3A-202 DNMT3A Q9Y6K1 DNA (cytosine-5)-methyltransferase 3A chr2 GO:0071456 Census, Compendium Yes 143 0.156798245614035 372 44 0.0482456140350877 14
EDN1-201 EDN1 P05305 Endothelin-1 chr6 GO:0071456 Not Cancer Driver No 27 0.1273584905660377 98 16 0.0754716981132075 3
EGLN1-201 EGLN1 Q9GZT9 Egl nine homolog 1 chr1 GO:0071456 Not Cancer Driver No 22 0.0516431924882629 206 4 0.0093896713615023 2
EGLN2-201 EGLN2 Q96KS0 Prolyl hydroxylase EGLN2 chr19 GO:0071456 Not Cancer Driver No 36 0.0884520884520884 204 9 0.0221130221130221 0
EGLN3-201 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 GO:0071456 Not Cancer Driver No 21 0.0878661087866108 13 0 0.0 0
EPAS1-201 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 GO:0071456 Census, Compendium Yes 109 0.125287356321839 451 54 0.0620689655172413 4
ERO1A-201 ERO1A Q96HE7 ERO1-like protein alpha chr14 GO:0071456 Not Cancer Driver No 34 0.0726495726495726 33 4 0.0085470085470085 0
FABP1-201 FABP1 P07148 Fatty acid-binding protein, liver chr2 GO:0071456 Not Cancer Driver No 23 0.1811023622047244 0 0 0.0 0
FAM162A-203 FAM162A Q96A26 Protein FAM162A chr3 GO:0071456 Not Cancer Driver No 10 0.0649350649350649 53 4 0.0259740259740259 0
FGFR2-206 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0071456 Census, Compendium Yes 193 0.2350791717417783 229 34 0.0414129110840438 57
FMN2-201 FMN2 Q9NZ56 Formin-2 chr1 GO:0071456 Not Cancer Driver No 222 0.1289198606271777 1327 218 0.1265969802555168 0
FOS-201 FOS P01100 Protein c-Fos chr14 GO:0071456 Not Cancer Driver No 37 0.0973684210526315 247 28 0.0736842105263157 0
FOXO3-202 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0071456 Census, Compendium Yes 54 0.0802377414561664 597 50 0.0742942050520059 0
GATA6-201 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0071456 Not Cancer Driver No 45 0.0756302521008403 478 39 0.0655462184873949 15
GNGT1-201 GNGT1 P63211 Guanine nucleotide-binding protein G(T) subunit gamma-T1 chr7 GO:0071456 Not Cancer Driver No 8 0.1081081081081081 25 2 0.027027027027027 0
HIF1A-202 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0071456 Census Yes 54 0.0653753026634382 436 28 0.0338983050847457 0
HILPDA-201 HILPDA Q9Y5L2 Hypoxia-inducible lipid droplet-associated protein chr7 GO:0071456 Not Cancer Driver No 4 0.0634920634920634 33 3 0.0476190476190476 0
HIPK2-202 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0071456 Not Cancer Driver No 124 0.1035058430717863 686 76 0.0634390651085141 0
HMOX1-201 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0071456 Not Cancer Driver No 33 0.1145833333333333 82 11 0.0381944444444444 0
HP1BP3-210 HP1BP3 Q5SSJ5 Heterochromatin protein 1-binding protein 3 chr1 GO:0071456 Not Cancer Driver No 42 0.0759493670886076 404 35 0.0632911392405063 0
HYOU1-218 HYOU1 Q9Y4L1 Hypoxia up-regulated protein 1 chr11 GO:0071456 Not Cancer Driver No 98 0.0980980980980981 373 36 0.036036036036036 0
INHBA-201 INHBA P08476 Inhibin beta A chain chr7 GO:0071456 Not Cancer Driver No 121 0.284037558685446 154 54 0.1267605633802817 0
IRAK1-203 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX GO:0071456 Compendium Yes 60 0.0842696629213483 338 35 0.0491573033707865 0
KCND2-201 KCND2 Q9NZV8 Potassium voltage-gated channel subfamily D member 2 chr7 GO:0071456 Not Cancer Driver No 175 0.2777777777777778 195 51 0.0809523809523809 1
KCNK2-203 KCNK2 O95069 Potassium channel subfamily K member 2 chr1 GO:0071456 Not Cancer Driver No 92 0.215962441314554 40 11 0.0258215962441314 0
KCNK3-201 KCNK3 O14649 Potassium channel subfamily K member 3 chr2 GO:0071456 Not Cancer Driver No 44 0.1116751269035533 61 6 0.015228426395939 6
KCNMB1-201 KCNMB1 Q16558 Calcium-activated potassium channel subunit beta-1 chr5 GO:0071456 Not Cancer Driver No 44 0.2303664921465968 0 0 0.0 0
LMNA-205 LMNA P02545 Prelamin-A/C chr1 GO:0071456 Census Yes 50 0.0753012048192771 547 34 0.0512048192771084 117
MAP3K7-204 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0071456 Not Cancer Driver No 74 0.1221122112211221 333 42 0.0693069306930693 6
MDM2-224 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0071456 Census, Compendium Yes 39 0.0794297352342158 298 24 0.0488798370672097 0
MDM4-203 MDM4 O15151 Protein Mdm4 chr1 GO:0071456 Census, Compendium Yes 33 0.0673469387755102 203 15 0.0306122448979591 1
MGARP-201 MGARP Q8TDB4 Protein MGARP chr4 GO:0071456 Not Cancer Driver No 15 0.0625 209 14 0.0583333333333333 0
MIEF1-201 MIEF1 Q9NQG6 Mitochondrial dynamics protein MIEF1 chr22 GO:0071456 Not Cancer Driver No 45 0.0971922246220302 94 6 0.0129589632829373 0
MLST8-232 MLST8 Q9BVC4 Target of rapamycin complex subunit LST8 chr16 GO:0071456 Not Cancer Driver No 24 0.0736196319018405 45 3 0.00920245398773 0
MPL-201 MPL P40238 Thrombopoietin receptor chr1 GO:0071456 Census Yes 58 0.0913385826771653 129 15 0.0236220472440944 12
MSTN-201 MSTN O14793 Growth/differentiation factor 8 chr2 GO:0071456 Not Cancer Driver No 54 0.144 65 11 0.0293333333333333 0
MT3-201 MT3 P25713 Metallothionein-3 chr16 GO:0071456 Not Cancer Driver No 4 0.0588235294117647 0 0 0.0 0
MTOR-201 MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0071456 Census, Compendium Yes 298 0.1169085916045508 298 28 0.0109846998823067 15
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 GO:0071456 Census, Compendium Yes 72 0.158590308370044 325 41 0.0903083700440528 0
NDNF-201 NDNF Q8TB73 Protein NDNF chr4 GO:0071456 Not Cancer Driver No 90 0.1584507042253521 130 22 0.0387323943661971 1
NDP-202 NDP Q00604 Norrin chrX GO:0071456 Not Cancer Driver No 11 0.0827067669172932 0 0 0.0 45
NDRG1-201 NDRG1 Q92597 Protein NDRG1 chr8 GO:0071456 Census Yes 44 0.1116751269035533 141 18 0.0456852791878172 0
NFE2L2-201 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0071456 Census, Compendium Yes 235 0.3884297520661157 402 59 0.0975206611570247 4
NGB-201 NGB Q9NPG2 Neuroglobin chr14 GO:0071456 Not Cancer Driver No 16 0.1059602649006622 3 0 0.0 0
NKX3-1-201 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0071456 Not Cancer Driver No 26 0.1111111111111111 175 12 0.0512820512820512 0
NONO-201 NONO Q15233 Non-POU domain-containing octamer-binding protein chrX GO:0071456 Census, Compendium Yes 70 0.1486199575371549 349 46 0.0976645435244161 0
NOP53-201 NOP53 Q9NZM5 Ribosome biogenesis protein NOP53 chr19 GO:0071456 Not Cancer Driver No 36 0.0753138075313807 399 26 0.0543933054393305 0
NOTCH1-204 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0071456 Census, Compendium Yes 312 0.1221135029354207 690 71 0.0277886497064579 3
NPEPPS-201 NPEPPS P55786 Puromycin-sensitive aminopeptidase chr17 GO:0071456 Compendium Yes 69 0.0750816104461371 45 2 0.0021762785636561 0
OPRD1-201 OPRD1 P41143 Delta-type opioid receptor chr1 GO:0071456 Not Cancer Driver No 53 0.1424731182795699 30 2 0.0053763440860215 0
P4HB-201 P4HB P07237 Protein disulfide-isomerase chr17 GO:0071456 Not Cancer Driver No 41 0.0807086614173228 80 13 0.0255905511811023 1
PCK1-201 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0071456 Not Cancer Driver No 112 0.180064308681672 111 24 0.0385852090032154 1
PGK1-201 PGK1 P00558 Phosphoglycerate kinase 1 chrX GO:0071456 Not Cancer Driver No 44 0.105515587529976 40 3 0.0071942446043165 9
PHB2-203 PHB2 Q99623 Prohibitin-2 chr12 GO:0071456 Not Cancer Driver No 25 0.0836120401337792 26 4 0.0133779264214046 0
PINK1-201 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0071456 Not Cancer Driver No 46 0.0791738382099827 99 8 0.0137693631669535 24
PMAIP1-202 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:0071456 Not Cancer Driver No 2 0.037037037037037 23 1 0.0185185185185185 0
PPARD-203 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0071456 Not Cancer Driver No 51 0.1156462585034013 70 5 0.0113378684807256 0
PPARG-201 PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0071456 Census Yes 60 0.1188118811881188 44 3 0.0059405940594059 3
PRKAA1-204 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0071456 Not Cancer Driver No 54 0.0966010733452593 124 13 0.0232558139534883 0
PRKCE-201 PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0071456 Not Cancer Driver No 80 0.1085481682496607 170 16 0.0217096336499321 0
PTGIS-201 PTGIS Q16647 Prostacyclin synthase chr20 GO:0071456 Not Cancer Driver No 81 0.162 18 2 0.004 0
PTGS2-201 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0071456 Not Cancer Driver No 68 0.1125827814569536 31 4 0.0066225165562913 0
RGCC-201 RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0071456 Not Cancer Driver No 4 0.0291970802919708 81 2 0.0145985401459854 0
RORA-203 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0071456 Not Cancer Driver No 43 0.0822179732313575 181 11 0.0210325047801147 4
RPTOR-201 RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0071456 Not Cancer Driver No 149 0.1116104868913857 242 18 0.0134831460674157 0
SCN2A-202 SCN2A Q99250 Sodium channel protein type 2 subunit alpha chr2 GO:0071456 Not Cancer Driver No 363 0.1810473815461346 436 92 0.0458852867830423 73
SDHD-201 SDHD O14521 Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial chr11 GO:0071456 Census Yes 15 0.0943396226415094 0 0 0.0 10
SFRP1-201 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0071456 Not Cancer Driver No 31 0.0987261146496815 39 4 0.0127388535031847 0
SIRT1-201 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0071456 Not Cancer Driver No 43 0.0575635876840696 435 19 0.0254350736278447 0
SIRT2-201 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0071456 Not Cancer Driver No 40 0.1028277634961439 85 13 0.0334190231362467 0
SIRT4-201 SIRT4 Q9Y6E7 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial chr12 GO:0071456 Not Cancer Driver No 31 0.0987261146496815 4 0 0.0 0
SLC29A1-206 SLC29A1 Q99808 Equilibrative nucleoside transporter 1 chr6 GO:0071456 Not Cancer Driver No 38 0.0833333333333333 27 3 0.006578947368421 0
SLC2A4-201 SLC2A4 P14672 Solute carrier family 2, facilitated glucose transporter member 4 chr17 GO:0071456 Not Cancer Driver No 47 0.0923379174852652 44 6 0.0117878192534381 1
SLC8A3-203 SLC8A3 P57103 Sodium/calcium exchanger 3 chr14 GO:0071456 Not Cancer Driver No 222 0.2394822006472491 154 31 0.0334412081984897 0
SLC9A1-201 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:0071456 Not Cancer Driver No 57 0.0699386503067484 252 17 0.0208588957055214 1
SRC-204 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0071456 Census Yes 40 0.0746268656716417 130 10 0.0186567164179104 1
STC1-201 STC1 P52823 Stanniocalcin-1 chr8 GO:0071456 Not Cancer Driver No 45 0.1821862348178137 58 9 0.0364372469635627 0
STC2-201 STC2 O76061 Stanniocalcin-2 chr5 GO:0071456 Not Cancer Driver No 60 0.1986754966887417 112 28 0.0927152317880794 0
STUB1-201 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0071456 Not Cancer Driver No 29 0.0957095709570957 113 11 0.0363036303630363 11
SUV39H1-202 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX GO:0071456 Not Cancer Driver No 43 0.1043689320388349 15 1 0.0024271844660194 0
SUV39H2-202 SUV39H2 Q9H5I1 Histone-lysine N-methyltransferase SUV39H2 chr10 GO:0071456 Not Cancer Driver No 28 0.0682926829268292 23 1 0.0024390243902439 0
TBL2-201 TBL2 Q9Y4P3 Transducin beta-like protein 2 chr7 GO:0071456 Not Cancer Driver No 43 0.0961968680089485 115 5 0.0111856823266219 0
TERT-201 TERT O14746 Telomerase reverse transcriptase chr5 GO:0071456 Census Yes 86 0.0759717314487632 213 11 0.0097173144876325 32
TGFB1-201 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0071456 Not Cancer Driver No 30 0.0769230769230769 44 3 0.0076923076923076 8
TIGAR-201 TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0071456 Not Cancer Driver No 33 0.1222222222222222 39 8 0.0296296296296296 0
TP53-201 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0071456 Census, Compendium Yes 2742 6.977099236641221 282 1364 3.470737913486005 60
TREM2-202 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0071456 Not Cancer Driver No 31 0.1347826086956521 27 2 0.008695652173913 1
TWIST1-201 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0071456 Not Cancer Driver No 21 0.1039603960396039 132 9 0.0445544554455445 6
UBQLN1-202 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 GO:0071456 Not Cancer Driver No 40 0.0679117147707979 545 38 0.064516129032258 0
UCN3-201 UCN3 Q969E3 Urocortin-3 chr10 GO:0071456 Not Cancer Driver No 16 0.0993788819875776 74 8 0.0496894409937888 0
VASN-201 VASN Q6EMK4 Vasorin chr16 GO:0071456 Not Cancer Driver No 29 0.0430906389301634 234 7 0.0104011887072808 0
VEGFA-226 VEGFA P15692 Vascular endothelial growth factor A, long form chr6 GO:0071456 Not Cancer Driver No 24 0.060759493670886 215 9 0.0227848101265822 0
VHL-201 VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 GO:0071456 Census, Compendium Yes 85 0.3990610328638497 117 15 0.0704225352112676 84
ZFP36L1-202 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0071456 Compendium Yes 50 0.1479289940828402 212 26 0.0769230769230769 0