Total number of protein in "GO:0072089" GO term: 49
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCB1-211 | ABCB1 | P08183 | ATP-dependent translocase ABCB1 | chr7 | GO:0072089 | Compendium | Yes | 275 | 0.21484375 | 103 | 15 | 0.01171875 | 0 |
| AXIN2-201 | AXIN2 | Q9Y2T1 | Axin-2 | chr17 | GO:0072089 | Census, Compendium | Yes | 82 | 0.0972716488730723 | 551 | 51 | 0.0604982206405693 | 0 |
| BYSL-201 | BYSL | Q13895 | Bystin | chr6 | GO:0072089 | Not Cancer Driver | No | 25 | 0.05720823798627 | 178 | 11 | 0.0251716247139588 | 0 |
| CD109-201 | CD109 | Q6YHK3 | CD109 antigen | chr6 | GO:0072089 | Not Cancer Driver | No | 151 | 0.1044982698961937 | 54 | 9 | 0.0062283737024221 | 0 |
| CD34-201 | CD34 | P28906 | Hematopoietic progenitor cell antigen CD34 | chr1 | GO:0072089 | Not Cancer Driver | No | 48 | 0.1246753246753246 | 221 | 24 | 0.0623376623376623 | 0 |
| CDKN2C-202 | CDKN2C | P42773 | Cyclin-dependent kinase 4 inhibitor C | chr1 | GO:0072089 | Census, Compendium | Yes | 17 | 0.1011904761904761 | 49 | 5 | 0.0297619047619047 | 0 |
| CTNNB1-201 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | GO:0072089 | Census, Compendium | Yes | 363 | 0.4647887323943662 | 288 | 291 | 0.3725992317541613 | 11 |
| ELL3-201 | ELL3 | Q9HB65 | RNA polymerase II elongation factor ELL3 | chr15 | GO:0072089 | Not Cancer Driver | No | 41 | 0.1032745591939546 | 187 | 12 | 0.0302267002518891 | 0 |
| ENST00000648873 | RNF43 | Q68DV7 | E3 ubiquitin-protein ligase RNF43 | chr17 | GO:0072089 | Census, Compendium | Yes | 99 | 0.127906976744186 | 414 | 42 | 0.0542635658914728 | 0 |
| ENST00000696133 | IRF6 | O14896 | Interferon regulatory factor 6 | chr1 | GO:0072089 | Not Cancer Driver | No | 73 | 0.1502057613168724 | 183 | 31 | 0.0637860082304526 | 42 |
| FGF10-201 | FGF10 | O15520 | Fibroblast growth factor 10 | chr5 | GO:0072089 | Not Cancer Driver | No | 42 | 0.2019230769230769 | 34 | 8 | 0.0384615384615384 | 2 |
| FGF2-201 | FGF2 | P09038 | Fibroblast growth factor 2 | chr4 | GO:0072089 | Not Cancer Driver | No | 17 | 0.0590277777777777 | 183 | 5 | 0.0173611111111111 | 0 |
| FGF4-201 | FGF4 | P08620 | Fibroblast growth factor 4 | chr11 | GO:0072089 | Not Cancer Driver | No | 15 | 0.0728155339805825 | 21 | 3 | 0.0145631067961165 | 0 |
| FGF8-202 | FGF8 | P55075 | Fibroblast growth factor 8 | chr10 | GO:0072089 | Not Cancer Driver | No | 27 | 0.1158798283261802 | 79 | 8 | 0.0343347639484978 | 6 |
| FGF9-201 | FGF9 | P31371 | Fibroblast growth factor 9 | chr13 | GO:0072089 | Not Cancer Driver | No | 33 | 0.1586538461538461 | 43 | 8 | 0.0384615384615384 | 1 |
| FGFR1-214 | FGFR1 | P11362 | Fibroblast growth factor receptor 1 | chr8 | GO:0072089 | Census, Compendium | Yes | 92 | 0.1119221411192214 | 231 | 26 | 0.0316301703163017 | 69 |
| GLI3-201 | GLI3 | P10071 | Transcriptional activator GLI3 | chr7 | GO:0072089 | Not Cancer Driver | No | 308 | 0.1949367088607595 | 1362 | 270 | 0.170886075949367 | 7 |
| HMX2-201 | HMX2 | A2RU54 | Homeobox protein HMX2 | chr10 | GO:0072089 | Not Cancer Driver | No | 29 | 0.1062271062271062 | 170 | 17 | 0.0622710622710622 | 0 |
| HOXA3-206 | HOXA3 | O43365 | Homeobox protein Hox-A3 | chr7 | GO:0072089 | Not Cancer Driver | No | 64 | 0.1444695259593679 | 418 | 64 | 0.1444695259593679 | 0 |
| IRF6-201 | IRF6 | O14896 | Interferon regulatory factor 6 | chr1 | GO:0072089 | Not Cancer Driver | No | 73 | 0.1563169164882226 | 174 | 31 | 0.0663811563169164 | 42 |
| KDF1-201 | KDF1 | Q8NAX2 | Keratinocyte differentiation factor 1 | chr1 | GO:0072089 | Not Cancer Driver | No | 43 | 0.1080402010050251 | 279 | 35 | 0.0879396984924623 | 0 |
| KDR-201 | KDR | P35968 | Vascular endothelial growth factor receptor 2 | chr4 | GO:0072089 | Census, Compendium | Yes | 276 | 0.2035398230088495 | 276 | 40 | 0.0294985250737463 | 2 |
| LIG4-202 | LIG4 | P49917 | DNA ligase 4 | chr13 | GO:0072089 | Not Cancer Driver | No | 103 | 0.1130625686059275 | 63 | 10 | 0.0109769484083424 | 2 |
| NES-201 | NES | P48681 | Nestin | chr1 | GO:0072089 | Not Cancer Driver | No | 203 | 0.1252313386798272 | 1485 | 189 | 0.1165946946329426 | 0 |
| NF1-202 | NF1 | P21359 | Neurofibromin | chr17 | GO:0072089 | Census, Compendium | Yes | 285 | 0.1003874603733709 | 406 | 36 | 0.0126805213103205 | 75 |
| NFIB-205 | NFIB | O00712 | Nuclear factor 1 B-type | chr9 | GO:0072089 | Census | Yes | 48 | 0.1142857142857142 | 254 | 26 | 0.0619047619047619 | 3 |
| OSR2-201 | OSR2 | Q8N2R0 | Protein odd-skipped-related 2 | chr8 | GO:0072089 | Not Cancer Driver | No | 47 | 0.1506410256410256 | 67 | 10 | 0.032051282051282 | 0 |
| OVOL1-201 | OVOL1 | O14753 | Putative transcription factor Ovo-like 1 | chr11 | GO:0072089 | Not Cancer Driver | No | 25 | 0.0936329588014981 | 70 | 11 | 0.0411985018726591 | 0 |
| PBX1-203 | PBX1 | P40424 | Pre-B-cell leukemia transcription factor 1 | chr1 | GO:0072089 | Census | Yes | 64 | 0.1488372093023255 | 291 | 44 | 0.1023255813953488 | 0 |
| PRRX1-201 | PRRX1 | P54821 | Paired mesoderm homeobox protein 1 | chr1 | GO:0072089 | Census, Compendium | Yes | 54 | 0.2204081632653061 | 206 | 37 | 0.1510204081632653 | 1 |
| PTCH1-201 | PTCH1 | Q13635 | Protein patched homolog 1 | chr9 | GO:0072089 | Census, Compendium | Yes | 156 | 0.1078092605390463 | 383 | 39 | 0.0269523151347615 | 17 |
| RARB-214 | RARB | P10826 | Retinoic acid receptor beta | chr3 | GO:0072089 | Not Cancer Driver | No | 60 | 0.1318681318681318 | 148 | 17 | 0.0373626373626373 | 3 |
| RARG-203 | RARG | P13631 | Retinoic acid receptor gamma | chr12 | GO:0072089 | Not Cancer Driver | No | 69 | 0.1519823788546255 | 164 | 24 | 0.052863436123348 | 0 |
| RBPJ-206 | RBPJ | Q06330 | Recombining binding protein suppressor of hairless | chr4 | GO:0072089 | Not Cancer Driver | No | 32 | 0.064 | 151 | 10 | 0.02 | 2 |
| RNF43-201 | RNF43 | Q68DV7 | E3 ubiquitin-protein ligase RNF43 | chr17 | GO:0072089 | Census, Compendium | Yes | 99 | 0.1264367816091954 | 440 | 46 | 0.0587484035759897 | 0 |
| RUNX2-212 | RUNX2 | Q13950 | Runt-related transcription factor 2 | chr6 | GO:0072089 | Not Cancer Driver | No | 50 | 0.0959692898272552 | 447 | 44 | 0.0844529750479846 | 30 |
| SFN-201 | SFN | P31947 | 14-3-3 protein sigma | chr1 | GO:0072089 | Not Cancer Driver | No | 16 | 0.064516129032258 | 75 | 3 | 0.0120967741935483 | 0 |
| SHH-201 | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:0072089 | Not Cancer Driver | No | 36 | 0.0779220779220779 | 139 | 11 | 0.0238095238095238 | 69 |
| SHOX2-202 | SHOX2 | O60902 | Short stature homeobox protein 2 | chr3 | GO:0072089 | Not Cancer Driver | No | 45 | 0.1359516616314199 | 200 | 29 | 0.0876132930513595 | 0 |
| SOX9-201 | SOX9 | P48436 | Transcription factor SOX-9 | chr17 | GO:0072089 | Compendium | Yes | 69 | 0.1355599214145383 | 497 | 66 | 0.1296660117878192 | 13 |
| TBX3-201 | TBX3 | O15119 | T-box transcription factor TBX3 | chr12 | GO:0072089 | Census, Compendium | Yes | 102 | 0.1372812920592193 | 353 | 52 | 0.0699865410497981 | 2 |
| TIAL1-205 | TIAL1 | Q01085 | Nucleolysin TIAR | chr10 | GO:0072089 | Not Cancer Driver | No | 24 | 0.064 | 122 | 9 | 0.024 | 0 |
| TP53-201 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0072089 | Census, Compendium | Yes | 2742 | 6.977099236641221 | 282 | 1364 | 3.470737913486005 | 60 |
| TP63-201 | TP63 | Q9H3D4 | Tumor protein 63 | chr3 | GO:0072089 | Census, Compendium | Yes | 198 | 0.2911764705882353 | 398 | 120 | 0.1764705882352941 | 21 |
| TRIM71-201 | TRIM71 | Q2Q1W2 | E3 ubiquitin-protein ligase TRIM71 | chr3 | GO:0072089 | Not Cancer Driver | No | 86 | 0.0990783410138248 | 163 | 13 | 0.0149769585253456 | 2 |
| WNT11-201 | WNT11 | O96014 | Protein Wnt-11 | chr11 | GO:0072089 | Not Cancer Driver | No | 37 | 0.1045197740112994 | 59 | 3 | 0.0084745762711864 | 0 |
| WNT3-201 | WNT3 | P56703 | Proto-oncogene Wnt-3 | chr17 | GO:0072089 | Not Cancer Driver | No | 44 | 0.1239436619718309 | 34 | 9 | 0.0253521126760563 | 0 |
| WNT7B-201 | WNT7B | P56706 | Protein Wnt-7b | chr22 | GO:0072089 | Not Cancer Driver | No | 41 | 0.1174785100286533 | 11 | 1 | 0.0028653295128939 | 0 |
| ZNRF3-203 | ZNRF3 | Q9ULT6 | E3 ubiquitin-protein ligase ZNRF3 | chr22 | GO:0072089 | Census, Compendium | Yes | 74 | 0.079059829059829 | 510 | 39 | 0.0416666666666666 | 0 |