Total number of protein in "GO:0090398" GO term: 57
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1-201 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0090398 | Census, Compendium | Yes | 106 | 0.0938053097345132 | 609 | 53 | 0.0469026548672566 | 2 |
| ATM-229 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0090398 | Census, Compendium | Yes | 358 | 0.1171465968586387 | 226 | 29 | 0.0094895287958115 | 41 |
| BRCA2-201 | BRCA2 | P51587 | Breast cancer type 2 susceptibility protein | chr13 | GO:0090398 | Census, Compendium | Yes | 310 | 0.0906963136337039 | 1545 | 152 | 0.0444704505558806 | 46 |
| CALR-201 | CALR | P27797 | Calreticulin | chr19 | GO:0090398 | Census | Yes | 28 | 0.0671462829736211 | 245 | 16 | 0.0383693045563549 | 0 |
| CDK2-201 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | GO:0090398 | Not Cancer Driver | No | 17 | 0.0570469798657718 | 0 | 0 | 0.0 | 0 |
| CDKN1A-201 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | GO:0090398 | Census, Compendium | Yes | 38 | 0.2317073170731707 | 121 | 25 | 0.1524390243902439 | 0 |
| CDKN1B-201 | CDKN1B | P46527 | Cyclin-dependent kinase inhibitor 1B | chr12 | GO:0090398 | Census, Compendium | Yes | 14 | 0.0707070707070707 | 199 | 14 | 0.0707070707070707 | 0 |
| CDKN2A-201 | CDKN2A | P42771 | Cyclin-dependent kinase inhibitor 2A | chr9 | GO:0090398 | Census, Compendium | Yes | 151 | 0.967948717948718 | 83 | 81 | 0.5192307692307693 | 30 |
| CDKN2B-201 | CDKN2B | P42772 | Cyclin-dependent kinase 4 inhibitor B | chr9 | GO:0090398 | Not Cancer Driver | No | 14 | 0.1014492753623188 | 67 | 2 | 0.0144927536231884 | 0 |
| CITED2-201 | CITED2 | Q99967 | Cbp/p300-interacting transactivator 2 | chr6 | GO:0090398 | Not Cancer Driver | No | 22 | 0.0814814814814814 | 232 | 19 | 0.0703703703703703 | 0 |
| COMP-201 | COMP | P49747 | Cartilage oligomeric matrix protein | chr19 | GO:0090398 | Not Cancer Driver | No | 75 | 0.0990752972258916 | 307 | 39 | 0.0515191545574636 | 51 |
| DNAJA3-201 | DNAJA3 | Q96EY1 | DnaJ homolog subfamily A member 3, mitochondrial | chr16 | GO:0090398 | Not Cancer Driver | No | 44 | 0.0916666666666666 | 152 | 19 | 0.0395833333333333 | 0 |
| ECRG4-201 | ECRG4 | Q9H1Z8 | Augurin | chr2 | GO:0090398 | Not Cancer Driver | No | 26 | 0.1756756756756756 | 23 | 5 | 0.0337837837837837 | 0 |
| FBXO4-201 | FBXO4 | Q9UKT5 | F-box only protein 4 | chr5 | GO:0090398 | Not Cancer Driver | No | 38 | 0.0981912144702842 | 68 | 6 | 0.0155038759689922 | 0 |
| H2AX-202 | H2AX | P16104 | Histone H2AX | chr11 | GO:0090398 | Not Cancer Driver | No | 19 | 0.1328671328671328 | 68 | 8 | 0.0559440559440559 | 0 |
| HRAS-201 | HRAS | P01112 | GTPase HRas | chr11 | GO:0090398 | Census, Compendium | Yes | 129 | 0.6825396825396826 | 16 | 2 | 0.0105820105820105 | 10 |
| ID2-203 | ID2 | Q02363 | DNA-binding protein inhibitor ID-2 | chr2 | GO:0090398 | Not Cancer Driver | No | 13 | 0.0970149253731343 | 52 | 6 | 0.044776119402985 | 0 |
| IGF1R-217 | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:0090398 | Not Cancer Driver | No | 143 | 0.1046086320409656 | 265 | 30 | 0.021945866861741 | 6 |
| KAT5-203 | KAT5 | Q92993 | Histone acetyltransferase KAT5 | chr11 | GO:0090398 | Not Cancer Driver | No | 45 | 0.087719298245614 | 174 | 16 | 0.0311890838206627 | 3 |
| KAT6A-201 | KAT6A | Q92794 | Histone acetyltransferase KAT6A | chr8 | GO:0090398 | Census, Compendium | Yes | 119 | 0.0593812375249501 | 1424 | 67 | 0.0334331337325349 | 0 |
| LMNA-205 | LMNA | P02545 | Prelamin-A/C | chr1 | GO:0090398 | Census | Yes | 50 | 0.0753012048192771 | 547 | 34 | 0.0512048192771084 | 117 |
| MAGEA2-210 | MAGEA2B | P43356 | Melanoma-associated antigen 2 | chrX | GO:0090398 | Not Cancer Driver | No | 0 | 0.0 | 113 | 0 | 0.0 | 0 |
| MAGEA2B-212 | MAGEA2B | P43356 | Melanoma-associated antigen 2 | chrX | GO:0090398 | Not Cancer Driver | No | 0 | 0.0 | 113 | 0 | 0.0 | 0 |
| MAP2K1-201 | MAP2K1 | Q02750 | Dual specificity mitogen-activated protein kinase kinase 1 | chr15 | GO:0090398 | Census, Compendium | Yes | 83 | 0.2111959287531806 | 96 | 22 | 0.0559796437659033 | 5 |
| MAP2K3-202 | MAP2K3 | P46734 | Dual specificity mitogen-activated protein kinase kinase 3 | chr17 | GO:0090398 | Not Cancer Driver | No | 74 | 0.2132564841498559 | 76 | 19 | 0.0547550432276657 | 0 |
| MAP2K4-201 | MAP2K4 | P45985 | Dual specificity mitogen-activated protein kinase kinase 4 | chr17 | GO:0090398 | Census, Compendium | Yes | 72 | 0.1804511278195488 | 137 | 23 | 0.0576441102756892 | 0 |
| MAP2K6-206 | MAP2K6 | P52564 | Dual specificity mitogen-activated protein kinase kinase 6 | chr17 | GO:0090398 | Not Cancer Driver | No | 28 | 0.0838323353293413 | 55 | 6 | 0.0179640718562874 | 0 |
| MAP2K7-201 | MAP2K7 | O14733 | Dual specificity mitogen-activated protein kinase kinase 7 | chr19 | GO:0090398 | Compendium | Yes | 78 | 0.1861575178997613 | 145 | 17 | 0.0405727923627685 | 0 |
| MAP3K5-201 | MAP3K5 | Q99683 | Mitogen-activated protein kinase kinase kinase 5 | chr6 | GO:0090398 | Not Cancer Driver | No | 146 | 0.106259097525473 | 244 | 23 | 0.0167394468704512 | 0 |
| MAPK10-319 | MAPK10 | P53779 | Mitogen-activated protein kinase 10 | chr4 | GO:0090398 | Not Cancer Driver | No | 72 | 0.1551724137931034 | 107 | 15 | 0.0323275862068965 | 0 |
| MAPK11-201 | MAPK11 | Q15759 | Mitogen-activated protein kinase 11 | chr22 | GO:0090398 | Not Cancer Driver | No | 22 | 0.0604395604395604 | 64 | 2 | 0.0054945054945054 | 0 |
| MAPK14-201 | MAPK14 | Q16539 | Mitogen-activated protein kinase 14 | chr6 | GO:0090398 | Not Cancer Driver | No | 22 | 0.0611111111111111 | 25 | 0 | 0.0 | 0 |
| MAPK8-206 | MAPK8 | P45983 | Mitogen-activated protein kinase 8 | chr10 | GO:0090398 | Not Cancer Driver | No | 52 | 0.1217798594847775 | 94 | 9 | 0.0210772833723653 | 0 |
| MAPK9-207 | MAPK9 | P45984 | Mitogen-activated protein kinase 9 | chr5 | GO:0090398 | Not Cancer Driver | No | 37 | 0.0872641509433962 | 90 | 3 | 0.0070754716981132 | 0 |
| MAPKAPK5-207 | MAPKAPK5 | Q8IW41 | MAP kinase-activated protein kinase 5 | chr12 | GO:0090398 | Not Cancer Driver | No | 38 | 0.080338266384778 | 101 | 6 | 0.0126849894291754 | 0 |
| MIF-201 | MIF | P14174 | Macrophage migration inhibitory factor | chr22 | GO:0090398 | Not Cancer Driver | No | 4 | 0.0347826086956521 | 0 | 0 | 0.0 | 0 |
| MNT-201 | MNT | Q99583 | Max-binding protein MNT | chr17 | GO:0090398 | Not Cancer Driver | No | 27 | 0.0463917525773195 | 544 | 27 | 0.0463917525773195 | 0 |
| NPM1-201 | NPM1 | P06748 | Nucleophosmin | chr5 | GO:0090398 | Census, Compendium | Yes | 25 | 0.0850340136054421 | 249 | 19 | 0.064625850340136 | 0 |
| NSMCE2-201 | NSMCE2 | Q96MF7 | E3 SUMO-protein ligase NSE2 | chr8 | GO:0090398 | Not Cancer Driver | No | 18 | 0.0728744939271255 | 119 | 10 | 0.0404858299595141 | 0 |
| NUP62-201 | NUP62 | P37198 | Nuclear pore glycoprotein p62 | chr19 | GO:0090398 | Not Cancer Driver | No | 55 | 0.1053639846743295 | 378 | 39 | 0.0747126436781609 | 1 |
| OPA1-204 | OPA1 | O60313 | Dynamin-like 120 kDa protein, mitochondrial | chr3 | GO:0090398 | Not Cancer Driver | No | 86 | 0.0895833333333333 | 131 | 14 | 0.0145833333333333 | 58 |
| PML-201 | PML | P29590 | Protein PML | chr15 | GO:0090398 | Census, Compendium | Yes | 87 | 0.0986394557823129 | 312 | 28 | 0.0317460317460317 | 0 |
| PRELP-201 | PRELP | P51888 | Prolargin | chr1 | GO:0090398 | Not Cancer Driver | No | 57 | 0.1492146596858638 | 55 | 11 | 0.0287958115183246 | 0 |
| PRKCD-201 | PRKCD | Q05655 | Protein kinase C delta type | chr3 | GO:0090398 | Compendium | Yes | 52 | 0.0769230769230769 | 43 | 7 | 0.0103550295857988 | 0 |
| PRMT6-201 | PRMT6 | Q96LA8 | Protein arginine N-methyltransferase 6 | chr1 | GO:0090398 | Not Cancer Driver | No | 35 | 0.0933333333333333 | 71 | 5 | 0.0133333333333333 | 0 |
| SMC5-201 | SMC5 | Q8IY18 | Structural maintenance of chromosomes protein 5 | chr9 | GO:0090398 | Not Cancer Driver | No | 94 | 0.0853769300635785 | 381 | 35 | 0.0317892824704813 | 1 |
| SMC6-207 | SMC6 | Q96SB8 | Structural maintenance of chromosomes protein 6 | chr2 | GO:0090398 | Not Cancer Driver | No | 95 | 0.0870760769935838 | 459 | 43 | 0.0394133822181484 | 0 |
| SRF-201 | SRF | P11831 | Serum response factor | chr6 | GO:0090398 | Not Cancer Driver | No | 30 | 0.0590551181102362 | 443 | 29 | 0.0570866141732283 | 0 |
| TBX2-201 | TBX2 | Q13207 | T-box transcription factor TBX2 | chr17 | GO:0090398 | Not Cancer Driver | No | 64 | 0.0898876404494382 | 401 | 30 | 0.0421348314606741 | 1 |
| TBX3-201 | TBX3 | O15119 | T-box transcription factor TBX3 | chr12 | GO:0090398 | Census, Compendium | Yes | 102 | 0.1372812920592193 | 353 | 52 | 0.0699865410497981 | 2 |
| TERF2-201 | TERF2 | Q15554 | Telomeric repeat-binding factor 2 | chr16 | GO:0090398 | Not Cancer Driver | No | 26 | 0.047970479704797 | 361 | 15 | 0.0276752767527675 | 0 |
| TOP2B-201 | TOP2B | Q02880 | DNA topoisomerase 2-beta | chr3 | GO:0090398 | Not Cancer Driver | No | 82 | 0.050430504305043 | 545 | 27 | 0.0166051660516605 | 4 |
| TP53-201 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0090398 | Census, Compendium | Yes | 2742 | 6.977099236641221 | 282 | 1364 | 3.470737913486005 | 60 |
| TP63-201 | TP63 | Q9H3D4 | Tumor protein 63 | chr3 | GO:0090398 | Census, Compendium | Yes | 198 | 0.2911764705882353 | 398 | 120 | 0.1764705882352941 | 21 |
| ULK3-201 | ULK3 | Q6PHR2 | Serine/threonine-protein kinase ULK3 | chr15 | GO:0090398 | Not Cancer Driver | No | 26 | 0.0550847457627118 | 55 | 2 | 0.0042372881355932 | 0 |
| WRN-201 | WRN | Q14191 | Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN | chr8 | GO:0090398 | Census, Compendium | Yes | 133 | 0.092877094972067 | 374 | 29 | 0.0202513966480446 | 2 |
| ZMIZ1-201 | ZMIZ1 | Q9ULJ6 | Zinc finger MIZ domain-containing protein 1 | chr10 | GO:0090398 | Not Cancer Driver | No | 115 | 0.1077788191190253 | 764 | 83 | 0.077788191190253 | 4 |