Total number of protein in "GO:0098586" GO term: 79
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADAR-202 | ADAR | P55265 | Double-stranded RNA-specific adenosine deaminase | chr1 | GO:0098586 | Not Cancer Driver | No | 102 | 0.0831973898858075 | 677 | 56 | 0.0456769983686786 | 12 |
| ARF1-201 | ARF1 | P84077 | ADP-ribosylation factor 1 | chr1 | GO:0098586 | Not Cancer Driver | No | 22 | 0.1215469613259668 | 4 | 2 | 0.011049723756906 | 2 |
| ATF2-201 | ATF2 | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | chr2 | GO:0098586 | Not Cancer Driver | No | 42 | 0.0831683168316831 | 451 | 36 | 0.0712871287128712 | 0 |
| BAX-202 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0098586 | Census | Yes | 24 | 0.125 | 39 | 2 | 0.0104166666666666 | 0 |
| CALR-201 | CALR | P27797 | Calreticulin | chr19 | GO:0098586 | Census | Yes | 28 | 0.0671462829736211 | 245 | 16 | 0.0383693045563549 | 0 |
| CCL19-201 | CCL19 | Q99731 | C-C motif chemokine 19 | chr9 | GO:0098586 | Not Cancer Driver | No | 5 | 0.0510204081632653 | 7 | 0 | 0.0 | 0 |
| CCL5-201 | CCL5 | P13501 | C-C motif chemokine 5 | chr17 | GO:0098586 | Not Cancer Driver | No | 7 | 0.0769230769230769 | 0 | 0 | 0.0 | 0 |
| CHUK-201 | CHUK | O15111 | Inhibitor of nuclear factor kappa-B kinase subunit alpha | chr10 | GO:0098586 | Not Cancer Driver | No | 49 | 0.0657718120805369 | 116 | 7 | 0.0093959731543624 | 0 |
| CXCL10-201 | CXCL10 | P02778 | C-X-C motif chemokine 10 | chr4 | GO:0098586 | Not Cancer Driver | No | 11 | 0.1122448979591836 | 12 | 1 | 0.010204081632653 | 0 |
| DDX3X-244 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | GO:0098586 | Census, Compendium | Yes | 91 | 0.1374622356495468 | 302 | 32 | 0.0483383685800604 | 18 |
| EIF5A-202 | EIF5A | P63241 | Eukaryotic translation initiation factor 5A-1 | chr17 | GO:0098586 | Not Cancer Driver | No | 29 | 0.1883116883116883 | 21 | 3 | 0.0194805194805194 | 5 |
| EXT1-201 | EXT1 | Q16394 | Exostosin-1 | chr8 | GO:0098586 | Census | Yes | 75 | 0.1005361930294906 | 60 | 7 | 0.0093833780160857 | 8 |
| FMR1-205 | FMR1 | Q06787 | Fragile X messenger ribonucleoprotein 1 | chrX | GO:0098586 | Not Cancer Driver | No | 92 | 0.1455696202531645 | 327 | 50 | 0.0791139240506329 | 3 |
| GBF1-223 | GBF1 | Q92538 | Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 | chr10 | GO:0098586 | Not Cancer Driver | No | 161 | 0.0866057019903173 | 670 | 62 | 0.0333512641204948 | 0 |
| GSDME-214 | GSDME | O60443 | Gasdermin-E | chr7 | GO:0098586 | Not Cancer Driver | No | 64 | 0.1290322580645161 | 14 | 2 | 0.0040322580645161 | 0 |
| HIF1A-202 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:0098586 | Census | Yes | 54 | 0.0653753026634382 | 436 | 28 | 0.0338983050847457 | 0 |
| HSP90AA1-201 | HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha | chr14 | GO:0098586 | Census, Compendium | Yes | 44 | 0.0601092896174863 | 258 | 15 | 0.0204918032786885 | 0 |
| IFI6-202 | IFI6 | P09912 | Interferon alpha-inducible protein 6 | chr1 | GO:0098586 | Not Cancer Driver | No | 9 | 0.0692307692307692 | 7 | 0 | 0.0 | 0 |
| IFIH1-206 | IFIH1 | Q9BYX4 | Interferon-induced helicase C domain-containing protein 1 | chr2 | GO:0098586 | Not Cancer Driver | No | 83 | 0.0809756097560975 | 288 | 27 | 0.0263414634146341 | 9 |
| IFNA1-201 | IFNA13 | P01562 | Interferon alpha-1/13 | chr9 | GO:0098586 | Not Cancer Driver | No | 23 | 0.1216931216931216 | 2 | 1 | 0.0052910052910052 | 0 |
| IFNA10-201 | IFNA10 | P01566 | Interferon alpha-10 | chr9 | GO:0098586 | Not Cancer Driver | No | 25 | 0.1322751322751322 | 1 | 0 | 0.0 | 0 |
| IFNA13-202 | IFNA13 | P01562 | Interferon alpha-1/13 | chr9 | GO:0098586 | Not Cancer Driver | No | 29 | 0.1526315789473684 | 2 | 0 | 0.0 | 0 |
| IFNA14-201 | IFNA14 | P01570 | Interferon alpha-14 | chr9 | GO:0098586 | Not Cancer Driver | No | 27 | 0.1428571428571428 | 1 | 1 | 0.0052910052910052 | 0 |
| IFNA16-201 | IFNA16 | P05015 | Interferon alpha-16 | chr9 | GO:0098586 | Not Cancer Driver | No | 51 | 0.2698412698412698 | 1 | 0 | 0.0 | 0 |
| IFNA17-201 | IFNA17 | P01571 | Interferon alpha-17 | chr9 | GO:0098586 | Not Cancer Driver | No | 29 | 0.1534391534391534 | 0 | 0 | 0.0 | 0 |
| IFNA2-201 | IFNA2 | P01563 | Interferon alpha-2 | chr9 | GO:0098586 | Not Cancer Driver | No | 24 | 0.1276595744680851 | 2 | 0 | 0.0 | 0 |
| IFNA21-201 | IFNA21 | P01568 | Interferon alpha-21 | chr9 | GO:0098586 | Not Cancer Driver | No | 23 | 0.1216931216931216 | 0 | 0 | 0.0 | 0 |
| IFNA4-201 | IFNA4 | P05014 | Interferon alpha-4 | chr9 | GO:0098586 | Not Cancer Driver | No | 30 | 0.1587301587301587 | 1 | 0 | 0.0 | 0 |
| IFNA5-201 | IFNA5 | P01569 | Interferon alpha-5 | chr9 | GO:0098586 | Not Cancer Driver | No | 27 | 0.1428571428571428 | 1 | 0 | 0.0 | 0 |
| IFNA6-202 | IFNA6 | P05013 | Interferon alpha-6 | chr9 | GO:0098586 | Not Cancer Driver | No | 21 | 0.1111111111111111 | 4 | 0 | 0.0 | 0 |
| IFNA7-201 | IFNA7 | P01567 | Interferon alpha-7 | chr9 | GO:0098586 | Not Cancer Driver | No | 33 | 0.1746031746031746 | 1 | 1 | 0.0052910052910052 | 0 |
| IFNA8-201 | IFNA8 | P32881 | Interferon alpha-8 | chr9 | GO:0098586 | Not Cancer Driver | No | 33 | 0.1746031746031746 | 0 | 0 | 0.0 | 0 |
| IFNAR1-201 | IFNAR1 | P17181 | Interferon alpha/beta receptor 1 | chr21 | GO:0098586 | Compendium | Yes | 36 | 0.0646319569120287 | 50 | 4 | 0.0071813285457809 | 0 |
| IFNAR2-202 | IFNAR2 | P48551 | Interferon alpha/beta receptor 2 | chr21 | GO:0098586 | Not Cancer Driver | No | 41 | 0.0796116504854368 | 199 | 19 | 0.0368932038834951 | 0 |
| IFNAR2-IL10RB-205 | IFNAR2 | P48551 | Interferon alpha/beta receptor 2 | chr21 | GO:0098586 | Not Cancer Driver | No | 0 | 0.0 | 0 | 0 | 0.0 | 0 |
| IFNB1-201 | IFNB1 | P01574 | Interferon beta | chr9 | GO:0098586 | Not Cancer Driver | No | 29 | 0.1550802139037433 | 0 | 0 | 0.0 | 0 |
| IFNE-201 | IFNE | Q86WN2 | Interferon epsilon | chr9 | GO:0098586 | Not Cancer Driver | No | 22 | 0.1057692307692307 | 17 | 3 | 0.0144230769230769 | 0 |
| IFNG-201 | IFNG | P01579 | Interferon gamma | chr12 | GO:0098586 | Not Cancer Driver | No | 34 | 0.2048192771084337 | 23 | 3 | 0.0180722891566265 | 0 |
| IFNGR1-201 | IFNGR1 | P15260 | Interferon gamma receptor 1 | chr6 | GO:0098586 | Compendium | Yes | 38 | 0.0777096114519427 | 176 | 13 | 0.0265848670756646 | 9 |
| IFNGR2-201 | IFNGR2 | P38484 | Interferon gamma receptor 2 | chr21 | GO:0098586 | Not Cancer Driver | No | 22 | 0.0652818991097922 | 18 | 1 | 0.0029673590504451 | 5 |
| IFNK-201 | IFNK | Q9P0W0 | Interferon kappa | chr9 | GO:0098586 | Not Cancer Driver | No | 13 | 0.0628019323671497 | 24 | 0 | 0.0 | 0 |
| IFNL1-201 | IFNL1 | Q8IU54 | Interferon lambda-1 | chr19 | GO:0098586 | Not Cancer Driver | No | 21 | 0.105 | 51 | 9 | 0.045 | 0 |
| IFNL2-201 | IFNL2 | Q8IZJ0 | Interferon lambda-2 | chr19 | GO:0098586 | Not Cancer Driver | No | 33 | 0.165 | 5 | 0 | 0.0 | 0 |
| IFNL3-201 | IFNL3 | Q8IZI9 | Interferon lambda-3 | chr19 | GO:0098586 | Not Cancer Driver | No | 32 | 0.1632653061224489 | 26 | 4 | 0.0204081632653061 | 0 |
| IFNLR1-201 | IFNLR1 | Q8IU57 | Interferon lambda receptor 1 | chr1 | GO:0098586 | Not Cancer Driver | No | 43 | 0.0826923076923076 | 256 | 30 | 0.0576923076923076 | 0 |
| IFNW1-201 | IFNW1 | P05000 | Interferon omega-1 | chr9 | GO:0098586 | Not Cancer Driver | No | 28 | 0.1435897435897435 | 10 | 3 | 0.0153846153846153 | 0 |
| IKBKE-203 | IKBKE | Q14164 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon | chr1 | GO:0098586 | Not Cancer Driver | No | 90 | 0.1256983240223463 | 76 | 10 | 0.0139664804469273 | 0 |
| IL10RB-201 | IL10RB | Q08334 | Interleukin-10 receptor subunit beta | chr21 | GO:0098586 | Not Cancer Driver | No | 36 | 0.1107692307692307 | 39 | 5 | 0.0153846153846153 | 0 |
| IL12A-207 | IL12A | P29459 | Interleukin-12 subunit alpha | chr3 | GO:0098586 | Not Cancer Driver | No | 25 | 0.1141552511415525 | 6 | 1 | 0.0045662100456621 | 0 |
| IL21-203 | IL21 | Q9HBE4 | Interleukin-21 | chr4 | GO:0098586 | Not Cancer Driver | No | 28 | 0.1728395061728395 | 71 | 13 | 0.0802469135802469 | 1 |
| IL6-201 | IL6 | P05231 | Interleukin-6 | chr7 | GO:0098586 | Not Cancer Driver | No | 32 | 0.1509433962264151 | 58 | 6 | 0.0283018867924528 | 0 |
| IRF3-203 | IRF3 | Q14653 | Interferon regulatory factor 3 | chr19 | GO:0098586 | Not Cancer Driver | No | 23 | 0.0538641686182669 | 205 | 17 | 0.0398126463700234 | 1 |
| IRF5-207 | IRF5 | Q13568 | Interferon regulatory factor 5 | chr7 | GO:0098586 | Not Cancer Driver | No | 44 | 0.0883534136546184 | 237 | 29 | 0.0582329317269076 | 0 |
| IRGM-202 | IRGM | A1A4Y4 | Immunity-related GTPase family M protein | chr5 | GO:0098586 | Not Cancer Driver | No | 7 | 0.0386740331491712 | 51 | 0 | 0.0 | 0 |
| JAK1-201 | JAK1 | P23458 | Tyrosine-protein kinase JAK1 | chr1 | GO:0098586 | Census, Compendium | Yes | 109 | 0.0944540727902946 | 120 | 6 | 0.0051993067590987 | 2 |
| JAK2-201 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | GO:0098586 | Census, Compendium | Yes | 81 | 0.0715547703180212 | 59 | 4 | 0.0035335689045936 | 4 |
| LGALS8-206 | LGALS8 | O00214 | Galectin-8 | chr1 | GO:0098586 | Not Cancer Driver | No | 30 | 0.0946372239747634 | 32 | 3 | 0.0094637223974763 | 0 |
| LGALS9-203 | LGALS9 | O00182 | Galectin-9 | chr17 | GO:0098586 | Not Cancer Driver | No | 46 | 0.1295774647887324 | 65 | 13 | 0.0366197183098591 | 0 |
| MAPK11-201 | MAPK11 | Q15759 | Mitogen-activated protein kinase 11 | chr22 | GO:0098586 | Not Cancer Driver | No | 22 | 0.0604395604395604 | 64 | 2 | 0.0054945054945054 | 0 |
| MAPK14-201 | MAPK14 | Q16539 | Mitogen-activated protein kinase 14 | chr6 | GO:0098586 | Not Cancer Driver | No | 22 | 0.0611111111111111 | 25 | 0 | 0.0 | 0 |
| MMP12-201 | MMP12 | P39900 | Macrophage metalloelastase | chr11 | GO:0098586 | Not Cancer Driver | No | 0 | 0.0 | 29 | 0 | 0.0 | 0 |
| NFKB1-205 | NFKB1 | P19838 | Nuclear factor NF-kappa-B p105 subunit | chr4 | GO:0098586 | Not Cancer Driver | No | 62 | 0.0640495867768595 | 345 | 30 | 0.03099173553719 | 0 |
| NLRP3-201 | NLRP3 | Q96P20 | NACHT, LRR and PYD domains-containing protein 3 | chr1 | GO:0098586 | Not Cancer Driver | No | 287 | 0.2775628626692456 | 65 | 30 | 0.0290135396518375 | 34 |
| OAS1-201 | OAS1 | P00973 | 2'-5'-oligoadenylate synthase 1 | chr12 | GO:0098586 | Not Cancer Driver | No | 42 | 0.105 | 73 | 0 | 0.0 | 4 |
| PENK-202 | PENK | P01210 | Proenkephalin-A | chr8 | GO:0098586 | Not Cancer Driver | No | 92 | 0.3445692883895131 | 143 | 55 | 0.2059925093632958 | 0 |
| POU2AF1-201 | POU2AF1 | Q16633 | POU domain class 2-associating factor 1 | chr11 | GO:0098586 | Census | Yes | 48 | 0.1875 | 181 | 36 | 0.140625 | 0 |
| POU2F2-204 | POU2F2 | P09086 | POU domain, class 2, transcription factor 2 | chr19 | GO:0098586 | Compendium | Yes | 66 | 0.1377870563674321 | 387 | 57 | 0.1189979123173277 | 0 |
| PYDC5-201 | PYDC5 | W6CW81 | Pyrin domain-containing protein 5 | chr1 | GO:0098586 | Not Cancer Driver | No | 0 | 0.0 | 5 | 0 | 0.0 | 0 |
| RIOK3-201 | RIOK3 | O14730 | Serine/threonine-protein kinase RIO3 | chr18 | GO:0098586 | Not Cancer Driver | No | 39 | 0.0751445086705202 | 225 | 15 | 0.0289017341040462 | 0 |
| RRP1B-201 | RRP1B | Q14684 | Ribosomal RNA processing protein 1 homolog B | chr21 | GO:0098586 | Not Cancer Driver | No | 61 | 0.0804749340369393 | 517 | 40 | 0.0527704485488126 | 0 |
| SMAD3-201 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0098586 | Census, Compendium | Yes | 80 | 0.188235294117647 | 113 | 15 | 0.0352941176470588 | 5 |
| TLR3-201 | TLR3 | O15455 | Toll-like receptor 3 | chr4 | GO:0098586 | Not Cancer Driver | No | 89 | 0.0984513274336283 | 0 | 0 | 0.0 | 1 |
| TLR7-201 | TLR7 | Q9NYK1 | Toll-like receptor 7 | chrX | GO:0098586 | Not Cancer Driver | No | 129 | 0.1229742612011439 | 14 | 1 | 0.0009532888465204 | 4 |
| TOMM70-201 | TOMM70 | O94826 | Mitochondrial import receptor subunit TOM70 | chr3 | GO:0098586 | Not Cancer Driver | No | 47 | 0.0773026315789473 | 141 | 7 | 0.0115131578947368 | 0 |
| TRIM6-201 | TRIM6 | Q9C030 | Tripartite motif-containing protein 6 | chr11 | GO:0098586 | Not Cancer Driver | No | 58 | 0.1188524590163934 | 48 | 12 | 0.0245901639344262 | 0 |
| TYK2-204 | TYK2 | P29597 | Non-receptor tyrosine-protein kinase TYK2 | chr19 | GO:0098586 | Not Cancer Driver | No | 118 | 0.0994102780117944 | 213 | 20 | 0.016849199663016 | 0 |
| VWCE-202 | VWCE | Q96DN2 | von Willebrand factor C and EGF domain-containing protein | chr11 | GO:0098586 | Not Cancer Driver | No | 104 | 0.1089005235602094 | 324 | 47 | 0.0492146596858638 | 0 |
| WDFY4-201 | WDFY4 | Q6ZS81 | WD repeat- and FYVE domain-containing protein 4 | chr10 | GO:0098586 | Not Cancer Driver | No | 146 | 0.0458542713567839 | 483 | 26 | 0.0081658291457286 | 0 |
| ZC3H12A-201 | ZC3H12A | Q5D1E8 | Endoribonuclease ZC3H12A | chr1 | GO:0098586 | Not Cancer Driver | No | 77 | 0.1285475792988314 | 397 | 38 | 0.0634390651085141 | 0 |