Total number of protein in "GO:1901224" GO term: 65
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACTN4-201 | ACTN4 | O43707 | Alpha-actinin-4 | chr19 | GO:1901224 | Not Cancer Driver | No | 110 | 0.1207464324917673 | 244 | 36 | 0.0395170142700329 | 7 |
| ADISSP-202 | ADISSP | Q9GZN8 | Adipose-secreted signaling protein | chr20 | GO:1901224 | Not Cancer Driver | No | 20 | 0.1149425287356321 | 31 | 1 | 0.0057471264367816 | 0 |
| AGER-206 | AGER | Q15109 | Advanced glycosylation end product-specific receptor | chr6 | GO:1901224 | Not Cancer Driver | No | 17 | 0.042079207920792 | 297 | 12 | 0.0297029702970297 | 0 |
| AGO3-203 | AGO3 | Q9H9G7 | Protein argonaute-3 | chr1 | GO:1901224 | Not Cancer Driver | No | 93 | 0.1081395348837209 | 143 | 18 | 0.0209302325581395 | 0 |
| APP-201 | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:1901224 | Not Cancer Driver | No | 94 | 0.122077922077922 | 419 | 52 | 0.0675324675324675 | 12 |
| C1QTNF4-201 | C1QTNF4 | Q9BXJ3 | Complement C1q tumor necrosis factor-related protein 4 | chr11 | GO:1901224 | Not Cancer Driver | No | 17 | 0.0516717325227963 | 91 | 4 | 0.0121580547112462 | 0 |
| CALR-201 | CALR | P27797 | Calreticulin | chr19 | GO:1901224 | Census | Yes | 28 | 0.0671462829736211 | 245 | 16 | 0.0383693045563549 | 0 |
| CCL19-201 | CCL19 | Q99731 | C-C motif chemokine 19 | chr9 | GO:1901224 | Not Cancer Driver | No | 5 | 0.0510204081632653 | 7 | 0 | 0.0 | 0 |
| CD27-201 | CD27 | P26842 | CD27 antigen | chr12 | GO:1901224 | Not Cancer Driver | No | 24 | 0.0923076923076923 | 92 | 10 | 0.0384615384615384 | 1 |
| CD86-202 | CD86 | P42081 | T-lymphocyte activation antigen CD86 | chr3 | GO:1901224 | Not Cancer Driver | No | 64 | 0.1945288753799392 | 56 | 10 | 0.0303951367781155 | 0 |
| DDX3X-244 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | GO:1901224 | Census, Compendium | Yes | 91 | 0.1374622356495468 | 302 | 32 | 0.0483383685800604 | 18 |
| EDA-203 | EDA | Q92838 | Ectodysplasin-A | chrX | GO:1901224 | Not Cancer Driver | No | 17 | 0.0434782608695652 | 243 | 1 | 0.0025575447570332 | 58 |
| EDAR-201 | EDAR | Q9UNE0 | Tumor necrosis factor receptor superfamily member EDAR | chr2 | GO:1901224 | Not Cancer Driver | No | 65 | 0.1450892857142857 | 117 | 16 | 0.0357142857142857 | 17 |
| EDN1-201 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:1901224 | Not Cancer Driver | No | 27 | 0.1273584905660377 | 98 | 16 | 0.0754716981132075 | 3 |
| EGFR-201 | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:1901224 | Census, Compendium | Yes | 346 | 0.2859504132231405 | 223 | 30 | 0.024793388429752 | 1 |
| EIF2AK2-201 | EIF2AK2 | P19525 | Interferon-induced, double-stranded RNA-activated protein kinase | chr2 | GO:1901224 | Not Cancer Driver | No | 36 | 0.0653357531760435 | 188 | 15 | 0.0272232304900181 | 1 |
| GREM1-203 | GREM1 | O60565 | Gremlin-1 | chr15 | GO:1901224 | Not Cancer Driver | No | 21 | 0.1141304347826086 | 77 | 9 | 0.0489130434782608 | 0 |
| HAVCR2-201 | HAVCR2 | Q8TDQ0 | Hepatitis A virus cellular receptor 2 | chr5 | GO:1901224 | Not Cancer Driver | No | 45 | 0.1495016611295681 | 17 | 1 | 0.0033222591362126 | 3 |
| IFI35-203 | IFI35 | P80217 | Interferon-induced 35 kDa protein | chr17 | GO:1901224 | Not Cancer Driver | No | 24 | 0.0839160839160839 | 63 | 10 | 0.0349650349650349 | 0 |
| IL12B-201 | IL12B | P29460 | Interleukin-12 subunit beta | chr5 | GO:1901224 | Not Cancer Driver | No | 37 | 0.1128048780487804 | 42 | 1 | 0.0030487804878048 | 0 |
| IL18-201 | IL18 | Q14116 | Interleukin-18 | chr11 | GO:1901224 | Not Cancer Driver | No | 11 | 0.0569948186528497 | 16 | 2 | 0.0103626943005181 | 0 |
| IL18R1-201 | IL18R1 | Q13478 | Interleukin-18 receptor 1 | chr2 | GO:1901224 | Not Cancer Driver | No | 86 | 0.1589648798521257 | 18 | 3 | 0.0055452865064695 | 0 |
| IL1B-201 | IL1B | P01584 | Interleukin-1 beta | chr2 | GO:1901224 | Not Cancer Driver | No | 32 | 0.1189591078066914 | 16 | 2 | 0.0074349442379182 | 0 |
| IL23A-201 | IL23A | Q9NPF7 | Interleukin-23 subunit alpha | chr12 | GO:1901224 | Not Cancer Driver | No | 7 | 0.037037037037037 | 42 | 2 | 0.0105820105820105 | 0 |
| LAPTM5-201 | LAPTM5 | Q13571 | Lysosomal-associated transmembrane protein 5 | chr1 | GO:1901224 | Not Cancer Driver | No | 34 | 0.1297709923664122 | 16 | 4 | 0.015267175572519 | 0 |
| LGALS9-203 | LGALS9 | O00182 | Galectin-9 | chr17 | GO:1901224 | Not Cancer Driver | No | 46 | 0.1295774647887324 | 65 | 13 | 0.0366197183098591 | 0 |
| LRRC19-201 | LRRC19 | Q9H756 | Leucine-rich repeat-containing protein 19 | chr9 | GO:1901224 | Not Cancer Driver | No | 24 | 0.0648648648648648 | 31 | 3 | 0.0081081081081081 | 0 |
| MAP3K7-204 | MAP3K7 | O43318 | Mitogen-activated protein kinase kinase kinase 7 | chr6 | GO:1901224 | Not Cancer Driver | No | 74 | 0.1221122112211221 | 333 | 42 | 0.0693069306930693 | 6 |
| NLRP12-201 | NLRP12 | P59046 | NACHT, LRR and PYD domains-containing protein 12 | chr19 | GO:1901224 | Not Cancer Driver | No | 258 | 0.2431668237511781 | 115 | 37 | 0.0348727615457115 | 0 |
| NLRP3-201 | NLRP3 | Q96P20 | NACHT, LRR and PYD domains-containing protein 3 | chr1 | GO:1901224 | Not Cancer Driver | No | 287 | 0.2775628626692456 | 65 | 30 | 0.0290135396518375 | 34 |
| NMI-201 | NMI | Q13287 | N-myc-interactor | chr2 | GO:1901224 | Not Cancer Driver | No | 22 | 0.0716612377850162 | 107 | 8 | 0.0260586319218241 | 0 |
| NOD1-201 | NOD1 | Q9Y239 | Nucleotide-binding oligomerization domain-containing protein 1 | chr7 | GO:1901224 | Not Cancer Driver | No | 98 | 0.1028331584470094 | 39 | 4 | 0.0041972717733473 | 0 |
| NOD2-201 | NOD2 | Q9HC29 | Nucleotide-binding oligomerization domain-containing protein 2 | chr16 | GO:1901224 | Not Cancer Driver | No | 130 | 0.125 | 41 | 3 | 0.0028846153846153 | 15 |
| NR3C2-203 | NR3C2 | P08235 | Mineralocorticoid receptor | chr4 | GO:1901224 | Not Cancer Driver | No | 120 | 0.1219512195121951 | 487 | 63 | 0.0640243902439024 | 14 |
| PDCD4-201 | PDCD4 | Q53EL6 | Programmed cell death protein 4 | chr10 | GO:1901224 | Not Cancer Driver | No | 49 | 0.1044776119402985 | 188 | 25 | 0.0533049040511727 | 0 |
| PHB1-201 | PHB1 | P35232 | Prohibitin 1 | chr17 | GO:1901224 | Not Cancer Driver | No | 21 | 0.0772058823529411 | 4 | 1 | 0.0036764705882352 | 0 |
| PHB2-203 | PHB2 | Q99623 | Prohibitin-2 | chr12 | GO:1901224 | Not Cancer Driver | No | 25 | 0.0836120401337792 | 26 | 4 | 0.0133779264214046 | 0 |
| PTP4A3-204 | PTP4A3 | O75365 | Protein tyrosine phosphatase type IVA 3 | chr8 | GO:1901224 | Not Cancer Driver | No | 27 | 0.1560693641618497 | 3 | 0 | 0.0 | 0 |
| PYCARD-201 | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:1901224 | Not Cancer Driver | No | 12 | 0.0615384615384615 | 39 | 4 | 0.0205128205128205 | 0 |
| RBCK1-202 | RBCK1 | Q9BYM8 | RanBP-type and C3HC4-type zinc finger-containing protein 1 | chr20 | GO:1901224 | Not Cancer Driver | No | 42 | 0.0823529411764705 | 141 | 14 | 0.0274509803921568 | 2 |
| RC3H1-203 | RC3H1 | Q5TC82 | Roquin-1 | chr1 | GO:1901224 | Not Cancer Driver | No | 114 | 0.1006178287731685 | 798 | 81 | 0.0714916151809355 | 0 |
| RC3H2-202 | RC3H2 | Q9HBD1 | Roquin-2 | chr9 | GO:1901224 | Not Cancer Driver | No | 99 | 0.0831234256926952 | 704 | 62 | 0.0520570948782535 | 0 |
| RELA-202 | RELA | Q04206 | Transcription factor p65 | chr11 | GO:1901224 | Compendium | Yes | 53 | 0.0961887477313974 | 401 | 32 | 0.058076225045372 | 0 |
| RHOA-202 | RHOA | P61586 | Transforming protein RhoA | chr3 | GO:1901224 | Census, Compendium | Yes | 92 | 0.4766839378238341 | 46 | 12 | 0.0621761658031088 | 2 |
| RIPK1-201 | RIPK1 | Q13546 | Receptor-interacting serine/threonine-protein kinase 1 | chr6 | GO:1901224 | Compendium | Yes | 59 | 0.0879284649776453 | 277 | 28 | 0.0417287630402384 | 1 |
| RPS3-217 | RPS3 | P23396 | Small ribosomal subunit protein uS3 | chr11 | GO:1901224 | Not Cancer Driver | No | 22 | 0.0905349794238683 | 48 | 4 | 0.0164609053497942 | 0 |
| RTKN2-202 | RTKN2 | Q8IZC4 | Rhotekin-2 | chr10 | GO:1901224 | Not Cancer Driver | No | 56 | 0.0919540229885057 | 160 | 20 | 0.0328407224958949 | 0 |
| SASH1-201 | SASH1 | O94885 | SAM and SH3 domain-containing protein 1 | chr6 | GO:1901224 | Not Cancer Driver | No | 132 | 0.1058540497193263 | 1077 | 124 | 0.0994386527666399 | 6 |
| SPHK1-210 | SPHK1 | Q9NYA1 | Sphingosine kinase 1 | chr17 | GO:1901224 | Not Cancer Driver | No | 29 | 0.0755208333333333 | 25 | 0 | 0.0 | 0 |
| TCIM-201 | TCIM | Q9NR00 | Transcriptional and immune response regulator | chr8 | GO:1901224 | Not Cancer Driver | No | 15 | 0.1415094339622641 | 33 | 5 | 0.0471698113207547 | 0 |
| TERF2IP-201 | TERF2IP | Q9NYB0 | Telomeric repeat-binding factor 2-interacting protein 1 | chr16 | GO:1901224 | Not Cancer Driver | No | 20 | 0.050125313283208 | 312 | 12 | 0.0300751879699248 | 0 |
| TLR2-203 | TLR2 | O60603 | Toll-like receptor 2 | chr4 | GO:1901224 | Not Cancer Driver | No | 84 | 0.1071428571428571 | 0 | 0 | 0.0 | 0 |
| TLR3-201 | TLR3 | O15455 | Toll-like receptor 3 | chr4 | GO:1901224 | Not Cancer Driver | No | 89 | 0.0984513274336283 | 0 | 0 | 0.0 | 1 |
| TLR4-201 | TLR4 | O00206 | Toll-like receptor 4 | chr9 | GO:1901224 | Not Cancer Driver | No | 253 | 0.301549463647199 | 0 | 0 | 0.0 | 0 |
| TLR7-201 | TLR7 | Q9NYK1 | Toll-like receptor 7 | chrX | GO:1901224 | Not Cancer Driver | No | 129 | 0.1229742612011439 | 14 | 1 | 0.0009532888465204 | 4 |
| TLR9-201 | TLR9 | Q9NR96 | Toll-like receptor 9 | chr3 | GO:1901224 | Not Cancer Driver | No | 107 | 0.1036821705426356 | 35 | 3 | 0.002906976744186 | 0 |
| TNF-208 | TNF | P01375 | Tumor necrosis factor | chr6 | GO:1901224 | Not Cancer Driver | No | 22 | 0.0944206008583691 | 45 | 2 | 0.0085836909871244 | 0 |
| TNFSF14-203 | TNFSF14 | O43557 | Tumor necrosis factor ligand superfamily member 14 | chr19 | GO:1901224 | Not Cancer Driver | No | 44 | 0.1833333333333333 | 19 | 2 | 0.0083333333333333 | 0 |
| TREM2-202 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:1901224 | Not Cancer Driver | No | 31 | 0.1347826086956521 | 27 | 2 | 0.008695652173913 | 1 |
| TRIM26-268 | TRIM26 | Q12899 | Tripartite motif-containing protein 26 | chr6 | GO:1901224 | Not Cancer Driver | No | 38 | 0.0705009276437847 | 153 | 5 | 0.0092764378478664 | 0 |
| TRIM44-201 | TRIM44 | Q96DX7 | Tripartite motif-containing protein 44 | chr11 | GO:1901224 | Not Cancer Driver | No | 20 | 0.0581395348837209 | 272 | 15 | 0.0436046511627907 | 1 |
| TRIM55-202 | TRIM55 | Q9BYV6 | Tripartite motif-containing protein 55 | chr8 | GO:1901224 | Not Cancer Driver | No | 100 | 0.1824817518248175 | 278 | 59 | 0.1076642335766423 | 0 |
| TRIM56-201 | TRIM56 | Q9BRZ2 | E3 ubiquitin-protein ligase TRIM56 | chr7 | GO:1901224 | Not Cancer Driver | No | 79 | 0.1046357615894039 | 221 | 31 | 0.0410596026490066 | 0 |
| TRIP6-201 | TRIP6 | Q15654 | Thyroid receptor-interacting protein 6 | chr7 | GO:1901224 | Not Cancer Driver | No | 48 | 0.1008403361344537 | 270 | 14 | 0.0294117647058823 | 0 |
| VCP-201 | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | GO:1901224 | Not Cancer Driver | No | 74 | 0.0918114143920595 | 186 | 14 | 0.0173697270471464 | 12 |