Total number of protein in "GO:2000045" GO term: 52
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACTB-217 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | GO:2000045 | Not Cancer Driver | No | 96 | 0.256 | 43 | 5 | 0.0133333333333333 | 4 |
| ACTL6A-202 | ACTL6A | O96019 | Actin-like protein 6A | chr3 | GO:2000045 | Not Cancer Driver | No | 39 | 0.0909090909090909 | 74 | 8 | 0.0186480186480186 | 1 |
| ACTL6B-201 | ACTL6B | O94805 | Actin-like protein 6B | chr7 | GO:2000045 | Not Cancer Driver | No | 64 | 0.1502347417840375 | 108 | 13 | 0.0305164319248826 | 3 |
| AMBRA1-213 | AMBRA1 | Q9C0C7 | Activating molecule in BECN1-regulated autophagy protein 1 | chr11 | GO:2000045 | Not Cancer Driver | No | 132 | 0.1016949152542373 | 790 | 80 | 0.061633281972265 | 0 |
| APPL1-201 | APPL1 | Q9UKG1 | DCC-interacting protein 13-alpha | chr3 | GO:2000045 | Not Cancer Driver | No | 35 | 0.0493653032440056 | 293 | 18 | 0.0253878702397743 | 1 |
| APPL2-201 | APPL2 | Q8NEU8 | DCC-interacting protein 13-beta | chr12 | GO:2000045 | Not Cancer Driver | No | 49 | 0.0737951807228915 | 149 | 8 | 0.0120481927710843 | 0 |
| ARID1A-201 | ARID1A | O14497 | AT-rich interactive domain-containing protein 1A | chr1 | GO:2000045 | Census, Compendium | Yes | 204 | 0.0892778993435448 | 1857 | 142 | 0.062144420131291 | 0 |
| ARID1B-203 | ARID1B | Q8NFD5 | AT-rich interactive domain-containing protein 1B | chr6 | GO:2000045 | Census, Compendium | Yes | 202 | 0.0871065114273393 | 1891 | 150 | 0.0646830530401035 | 2 |
| ARID2-201 | ARID2 | Q68CP9 | AT-rich interactive domain-containing protein 2 | chr12 | GO:2000045 | Census, Compendium | Yes | 205 | 0.1117166212534059 | 1144 | 111 | 0.0604904632152588 | 0 |
| BCL7A-201 | BCL7A | Q4VC05 | B-cell CLL/lymphoma 7 protein family member A | chr12 | GO:2000045 | Census, Compendium | Yes | 18 | 0.0857142857142857 | 207 | 17 | 0.0809523809523809 | 0 |
| BCL7B-201 | BCL7B | Q9BQE9 | B-cell CLL/lymphoma 7 protein family member B | chr7 | GO:2000045 | Not Cancer Driver | No | 16 | 0.0792079207920792 | 179 | 16 | 0.0792079207920792 | 0 |
| BCL7C-201 | BCL7C | Q8WUZ0 | B-cell CLL/lymphoma 7 protein family member C | chr16 | GO:2000045 | Not Cancer Driver | No | 24 | 0.1105990783410138 | 210 | 22 | 0.1013824884792626 | 0 |
| BID-211 | BID | P55957 | BH3-interacting domain death agonist | chr22 | GO:2000045 | Not Cancer Driver | No | 17 | 0.0871794871794871 | 75 | 5 | 0.0256410256410256 | 0 |
| BRD7-201 | BRD7 | Q9NPI1 | Bromodomain-containing protein 7 | chr16 | GO:2000045 | Compendium | Yes | 58 | 0.0890937019969278 | 485 | 33 | 0.0506912442396313 | 0 |
| CCNH-201 | CCNH | P51946 | Cyclin-H | chr5 | GO:2000045 | Not Cancer Driver | No | 23 | 0.0712074303405572 | 28 | 1 | 0.0030959752321981 | 0 |
| CDK7-201 | CDK7 | P50613 | Cyclin-dependent kinase 7 | chr5 | GO:2000045 | Not Cancer Driver | No | 25 | 0.0722543352601156 | 38 | 3 | 0.0086705202312138 | 0 |
| CDKN1A-201 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | GO:2000045 | Census, Compendium | Yes | 38 | 0.2317073170731707 | 121 | 25 | 0.1524390243902439 | 0 |
| CDKN1B-201 | CDKN1B | P46527 | Cyclin-dependent kinase inhibitor 1B | chr12 | GO:2000045 | Census, Compendium | Yes | 14 | 0.0707070707070707 | 199 | 14 | 0.0707070707070707 | 0 |
| CDKN2A-201 | CDKN2A | P42771 | Cyclin-dependent kinase inhibitor 2A | chr9 | GO:2000045 | Census, Compendium | Yes | 151 | 0.967948717948718 | 83 | 81 | 0.5192307692307693 | 30 |
| CDKN2B-201 | CDKN2B | P42772 | Cyclin-dependent kinase 4 inhibitor B | chr9 | GO:2000045 | Not Cancer Driver | No | 14 | 0.1014492753623188 | 67 | 2 | 0.0144927536231884 | 0 |
| CDKN2C-202 | CDKN2C | P42773 | Cyclin-dependent kinase 4 inhibitor C | chr1 | GO:2000045 | Census, Compendium | Yes | 17 | 0.1011904761904761 | 49 | 5 | 0.0297619047619047 | 0 |
| CDKN2D-202 | CDKN2D | P55273 | Cyclin-dependent kinase 4 inhibitor D | chr19 | GO:2000045 | Not Cancer Driver | No | 17 | 0.1024096385542168 | 45 | 3 | 0.0180722891566265 | 0 |
| DPF1-201 | DPF1 | Q92782 | Zinc finger protein neuro-d4 | chr19 | GO:2000045 | Not Cancer Driver | No | 27 | 0.0697674418604651 | 85 | 7 | 0.0180878552971576 | 0 |
| DPF2-205 | DPF2 | Q92785 | Zinc finger protein ubi-d4 | chr11 | GO:2000045 | Not Cancer Driver | No | 49 | 0.1253196930946291 | 179 | 21 | 0.0537084398976982 | 5 |
| DPF3-209 | DPF3 | Q92784 | Zinc finger protein DPF3 | chr14 | GO:2000045 | Not Cancer Driver | No | 51 | 0.1349206349206349 | 172 | 29 | 0.0767195767195767 | 0 |
| E2F1-201 | E2F1 | Q01094 | Transcription factor E2F1 | chr20 | GO:2000045 | Not Cancer Driver | No | 39 | 0.0892448512585812 | 273 | 17 | 0.0389016018306636 | 0 |
| ECD-201 | ECD | O95905 | Protein ecdysoneless homolog | chr10 | GO:2000045 | Not Cancer Driver | No | 44 | 0.0683229813664596 | 257 | 15 | 0.0232919254658385 | 0 |
| ID2-203 | ID2 | Q02363 | DNA-binding protein inhibitor ID-2 | chr2 | GO:2000045 | Not Cancer Driver | No | 13 | 0.0970149253731343 | 52 | 6 | 0.044776119402985 | 0 |
| INO80-209 | INO80 | Q9ULG1 | Chromatin-remodeling ATPase INO80 | chr15 | GO:2000045 | Compendium | Yes | 137 | 0.0880462724935732 | 682 | 67 | 0.0430591259640102 | 0 |
| KIF14-201 | KIF14 | Q15058 | Kinesin-like protein KIF14 | chr1 | GO:2000045 | Not Cancer Driver | No | 145 | 0.0879854368932038 | 777 | 65 | 0.0394417475728155 | 2 |
| KLF11-201 | KLF11 | O14901 | Krueppel-like factor 11 | chr2 | GO:2000045 | Not Cancer Driver | No | 45 | 0.087890625 | 310 | 32 | 0.0625 | 2 |
| MNAT1-201 | MNAT1 | P51948 | CDK-activating kinase assembly factor MAT1 | chr14 | GO:2000045 | Not Cancer Driver | No | 20 | 0.0647249190938511 | 64 | 2 | 0.0064724919093851 | 0 |
| PBRM1-201 | PBRM1 | Q86U86 | Protein polybromo-1 | chr3 | GO:2000045 | Census, Compendium | Yes | 162 | 0.0959147424511545 | 704 | 61 | 0.0361160449970396 | 0 |
| PHF10-201 | PHF10 | Q8WUB8 | PHD finger protein 10 | chr6 | GO:2000045 | Not Cancer Driver | No | 27 | 0.0542168674698795 | 298 | 21 | 0.0421686746987951 | 0 |
| PKD1-201 | PKD1 | P98161 | Polycystin-1 | chr16 | GO:2000045 | Not Cancer Driver | No | 299 | 0.0694864048338368 | 695 | 50 | 0.0116198001394376 | 91 |
| PLK5-202 | PLK5 | Q496M5 | Inactive serine/threonine-protein kinase PLK5 | chr19 | GO:2000045 | Not Cancer Driver | No | 7 | 0.0208333333333333 | 223 | 3 | 0.0089285714285714 | 0 |
| PPP2CA-203 | PPP2CA | P67775 | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform | chr5 | GO:2000045 | Not Cancer Driver | No | 32 | 0.1035598705501618 | 12 | 1 | 0.0032362459546925 | 7 |
| PSME1-201 | PSME1 | Q06323 | Proteasome activator complex subunit 1 | chr14 | GO:2000045 | Not Cancer Driver | No | 15 | 0.0602409638554216 | 80 | 7 | 0.0281124497991967 | 0 |
| PSME2-201 | PSME2 | Q9UL46 | Proteasome activator complex subunit 2 | chr14 | GO:2000045 | Not Cancer Driver | No | 29 | 0.1213389121338912 | 39 | 3 | 0.0125523012552301 | 0 |
| PSME3-210 | PSME3 | P61289 | Proteasome activator complex subunit 3 | chr17 | GO:2000045 | Not Cancer Driver | No | 16 | 0.0629921259842519 | 25 | 5 | 0.0196850393700787 | 0 |
| PTPN6-201 | PTPN6 | P29350 | Tyrosine-protein phosphatase non-receptor type 6 | chr12 | GO:2000045 | Census, Compendium | Yes | 52 | 0.0873949579831932 | 194 | 20 | 0.0336134453781512 | 0 |
| SMARCA2-203 | SMARCA2 | P51531 | Probable global transcription activator SNF2L2 | chr9 | GO:2000045 | Not Cancer Driver | No | 178 | 0.1119496855345912 | 1015 | 100 | 0.0628930817610062 | 36 |
| SMARCA4-201 | SMARCA4 | P51532 | Transcription activator BRG1 | chr19 | GO:2000045 | Census, Compendium | Yes | 300 | 0.1821493624772313 | 1078 | 163 | 0.0989678202792957 | 5 |
| SMARCB1-213 | SMARCB1 | Q12824 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 | chr22 | GO:2000045 | Census, Compendium | Yes | 55 | 0.1428571428571428 | 141 | 26 | 0.0675324675324675 | 3 |
| SMARCC1-201 | SMARCC1 | Q92922 | SWI/SNF complex subunit SMARCC1 | chr3 | GO:2000045 | Not Cancer Driver | No | 80 | 0.0723981900452488 | 721 | 50 | 0.0452488687782805 | 2 |
| SMARCC2-201 | SMARCC2 | Q8TAQ2 | SWI/SNF complex subunit SMARCC2 | chr12 | GO:2000045 | Not Cancer Driver | No | 99 | 0.0815485996705107 | 875 | 71 | 0.058484349258649 | 4 |
| SMARCD1-202 | SMARCD1 | Q96GM5 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 | chr12 | GO:2000045 | Census, Compendium | Yes | 37 | 0.0718446601941747 | 216 | 14 | 0.0271844660194174 | 2 |
| SMARCD2-203 | SMARCD2 | Q92925 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 | chr17 | GO:2000045 | Not Cancer Driver | No | 42 | 0.0790960451977401 | 251 | 15 | 0.0282485875706214 | 0 |
| SMARCD3-201 | SMARCD3 | Q6STE5 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 | chr7 | GO:2000045 | Not Cancer Driver | No | 41 | 0.0848861283643892 | 213 | 10 | 0.020703933747412 | 0 |
| SMARCE1-202 | SMARCE1 | Q969G3 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 | chr17 | GO:2000045 | Census | Yes | 36 | 0.0875912408759124 | 332 | 28 | 0.0681265206812652 | 1 |
| TM4SF5-201 | TM4SF5 | O14894 | Transmembrane 4 L6 family member 5 | chr17 | GO:2000045 | Not Cancer Driver | No | 24 | 0.1218274111675127 | 1 | 0 | 0.0 | 0 |
| TMEM14B-202 | TMEM14B | Q9NUH8 | Transmembrane protein 14B | chr6 | GO:2000045 | Not Cancer Driver | No | 13 | 0.1140350877192982 | 0 | 0 | 0.0 | 0 |