Total number of protein in "GO:2000378" GO term: 23
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AATF-208 | AATF | Q9NY61 | Protein AATF | chr17 | GO:2000378 | Not Cancer Driver | No | 45 | 0.0803571428571428 | 393 | 32 | 0.0571428571428571 | 0 |
ATG5-204 | ATG5 | Q9H1Y0 | Autophagy protein 5 | chr6 | GO:2000378 | Not Cancer Driver | No | 33 | 0.12 | 25 | 6 | 0.0218181818181818 | 1 |
BCL2-201 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:2000378 | Census, Compendium | Yes | 21 | 0.0878661087866108 | 73 | 5 | 0.0209205020920502 | 0 |
BCR-201 | BCR | P11274 | Breakpoint cluster region protein | chr22 | GO:2000378 | Census, Compendium | Yes | 112 | 0.088119590873328 | 607 | 57 | 0.044846577498033 | 0 |
BECN1-213 | BECN1 | Q14457 | Beclin-1 | chr17 | GO:2000378 | Not Cancer Driver | No | 36 | 0.08 | 190 | 15 | 0.0333333333333333 | 0 |
BNIP3-201 | BNIP3 | Q12983 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 | chr10 | GO:2000378 | Not Cancer Driver | No | 16 | 0.0824742268041237 | 131 | 11 | 0.056701030927835 | 0 |
BRCA1-203 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | GO:2000378 | Census, Compendium | Yes | 167 | 0.0896403650026838 | 1466 | 127 | 0.0681696188942565 | 34 |
CRYAB-217 | CRYAB | P02511 | Alpha-crystallin B chain | chr11 | GO:2000378 | Not Cancer Driver | No | 17 | 0.0971428571428571 | 59 | 7 | 0.04 | 5 |
G6PD-202 | G6PD | P11413 | Glucose-6-phosphate 1-dehydrogenase | chrX | GO:2000378 | Not Cancer Driver | No | 64 | 0.1242718446601941 | 28 | 3 | 0.0058252427184466 | 51 |
HIF1A-202 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:2000378 | Census | Yes | 54 | 0.0653753026634382 | 436 | 28 | 0.0338983050847457 | 0 |
HK2-201 | HK2 | P52789 | Hexokinase-2 | chr2 | GO:2000378 | Not Cancer Driver | No | 108 | 0.1177753544165757 | 78 | 2 | 0.0021810250817884 | 0 |
MMP3-201 | MMP3 | P08254 | Stromelysin-1 | chr11 | GO:2000378 | Not Cancer Driver | No | 74 | 0.1551362683438155 | 66 | 13 | 0.0272536687631027 | 0 |
PAX2-205 | PAX2 | Q02962 | Paired box protein Pax-2 | chr10 | GO:2000378 | Not Cancer Driver | No | 49 | 0.1175059952038369 | 294 | 39 | 0.0935251798561151 | 22 |
PINK1-201 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | GO:2000378 | Not Cancer Driver | No | 46 | 0.0791738382099827 | 99 | 8 | 0.0137693631669535 | 24 |
PLIN5-201 | PLIN5 | Q00G26 | Perilipin-5 | chr19 | GO:2000378 | Not Cancer Driver | No | 43 | 0.0928725701943844 | 194 | 17 | 0.0367170626349892 | 0 |
PRKN-206 | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:2000378 | Not Cancer Driver | No | 96 | 0.2064516129032258 | 78 | 14 | 0.0301075268817204 | 30 |
SIRT2-201 | SIRT2 | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | chr19 | GO:2000378 | Not Cancer Driver | No | 40 | 0.1028277634961439 | 85 | 13 | 0.0334190231362467 | 0 |
SIRT3-201 | SIRT3 | Q9NTG7 | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | chr11 | GO:2000378 | Not Cancer Driver | No | 25 | 0.06265664160401 | 60 | 2 | 0.0050125313283208 | 0 |
SIRT5-205 | SIRT5 | Q9NXA8 | NAD-dependent protein deacylase sirtuin-5, mitochondrial | chr6 | GO:2000378 | Not Cancer Driver | No | 22 | 0.0709677419354838 | 55 | 2 | 0.0064516129032258 | 0 |
TFAP2A-203 | TFAP2A | P05549 | Transcription factor AP-2-alpha | chr6 | GO:2000378 | Not Cancer Driver | No | 54 | 0.123006833712984 | 277 | 32 | 0.0728929384965831 | 4 |
TIGAR-201 | TIGAR | Q9NQ88 | Fructose-2,6-bisphosphatase TIGAR | chr12 | GO:2000378 | Not Cancer Driver | No | 33 | 0.1222222222222222 | 39 | 8 | 0.0296296296296296 | 0 |
TP53-201 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:2000378 | Census, Compendium | Yes | 2742 | 6.977099236641221 | 282 | 1364 | 3.470737913486005 | 60 |
VDAC1-201 | VDAC1 | P21796 | Voltage-dependent anion-selective channel protein 1 | chr5 | GO:2000378 | Not Cancer Driver | No | 25 | 0.0883392226148409 | 36 | 4 | 0.0141342756183745 | 0 |