Total number of protein in "GO:2000811" GO term: 18
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BCL2-201 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:2000811 | Census, Compendium | Yes | 21 | 0.0878661087866108 | 73 | 5 | 0.0209205020920502 | 0 |
CAV1-201 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:2000811 | Not Cancer Driver | No | 23 | 0.1292134831460674 | 2 | 0 | 0.0 | 0 |
CEACAM5-201 | CEACAM5 | P06731 | Carcinoembryonic antigen-related cell adhesion molecule 5 | chr19 | GO:2000811 | Not Cancer Driver | No | 113 | 0.1609686609686609 | 259 | 40 | 0.0569800569800569 | 0 |
CEACAM6-201 | CEACAM6 | P40199 | Carcinoembryonic antigen-related cell adhesion molecule 6 | chr19 | GO:2000811 | Not Cancer Driver | No | 40 | 0.1162790697674418 | 110 | 11 | 0.0319767441860465 | 0 |
ITGA5-201 | ITGA5 | P08648 | Integrin alpha-5 | chr12 | GO:2000811 | Not Cancer Driver | No | 89 | 0.0848427073403241 | 202 | 21 | 0.0200190657769304 | 0 |
ITGB1-201 | ITGB1 | P05556 | Integrin beta-1 | chr10 | GO:2000811 | Not Cancer Driver | No | 73 | 0.0914786967418546 | 84 | 8 | 0.0100250626566416 | 0 |
MCL1-202 | MCL1 | Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | chr1 | GO:2000811 | Not Cancer Driver | No | 27 | 0.0771428571428571 | 204 | 19 | 0.0542857142857142 | 0 |
NOTCH1-204 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:2000811 | Census, Compendium | Yes | 312 | 0.1221135029354207 | 690 | 71 | 0.0277886497064579 | 3 |
NTRK2-246 | NTRK2 | Q16620 | BDNF/NT-3 growth factors receptor | chr9 | GO:2000811 | Not Cancer Driver | No | 103 | 0.1253041362530413 | 117 | 14 | 0.0170316301703163 | 1 |
PDK4-201 | PDK4 | Q16654 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | chr7 | GO:2000811 | Not Cancer Driver | No | 45 | 0.1094890510948905 | 14 | 1 | 0.0024330900243309 | 0 |
PIK3CA-201 | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:2000811 | Census, Compendium | Yes | 1425 | 1.3342696629213484 | 38 | 9 | 0.0084269662921348 | 44 |
PIK3R3-201 | PIK3R3 | Q92569 | Phosphatidylinositol 3-kinase regulatory subunit gamma | chr1 | GO:2000811 | Not Cancer Driver | No | 42 | 0.0911062906724512 | 149 | 17 | 0.0368763557483731 | 0 |
PTK2-228 | PTK2 | Q05397 | Focal adhesion kinase 1 | chr8 | GO:2000811 | Not Cancer Driver | No | 102 | 0.0969581749049429 | 426 | 45 | 0.0427756653992395 | 0 |
PTRH2-201 | PTRH2 | Q9Y3E5 | Peptidyl-tRNA hydrolase 2, mitochondrial | chr17 | GO:2000811 | Not Cancer Driver | No | 7 | 0.0391061452513966 | 19 | 1 | 0.0055865921787709 | 1 |
SNAI2-201 | SNAI2 | O43623 | Zinc finger protein SNAI2 | chr8 | GO:2000811 | Not Cancer Driver | No | 43 | 0.1604477611940298 | 52 | 8 | 0.0298507462686567 | 0 |
SRC-204 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:2000811 | Census | Yes | 40 | 0.0746268656716417 | 130 | 10 | 0.0186567164179104 | 1 |
TLE1-203 | TLE1 | Q04724 | Transducin-like enhancer protein 1 | chr9 | GO:2000811 | Not Cancer Driver | No | 86 | 0.1116883116883116 | 385 | 39 | 0.0506493506493506 | 0 |
ZNF304-201 | ZNF304 | Q9HCX3 | Zinc finger protein 304 | chr19 | GO:2000811 | Not Cancer Driver | No | 78 | 0.1183611532625189 | 54 | 8 | 0.0121396054628224 | 0 |