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GPR37L1-201 ,GPR37L1 ,O60883
  • Uniprot Accession= O60883
  • Ensembl Transcript= ENST00000367282.6
  • Uniprot Name= GPR37L1
  • Name= G-protein coupled receptor 37-like 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 19
GO term GO name GO namespace GO def
GO:0036505 prosaposin receptor activity molecular_function Combining with prosaposin to initiate a change in cell activity. Prosaposin is the glycoprotein precursor of four cleavage products (saposins A, B, C and D). [GOC:bf, GOC:PARL, PMID:23690594, PMID:9388493]
GO:0004930 G protein-coupled receptor activity molecular_function Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. [GOC:bf, http://www.iuphar-db.org, Wikipedia:GPCR]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0008528 G protein-coupled peptide receptor activity molecular_function Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. [GOC:dph, GOC:tb]
GO:0042277 peptide binding molecular_function Binding to a peptide, an organic compound comprising two or more amino acids linked by peptide bonds. [GOC:jl]
GO:0003085 negative regulation of systemic arterial blood pressure biological_process The process that reduces the force with which blood travels through the systemic arterial circulatory system. [GOC:mtg_cardio]
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway biological_process A G protein-coupled receptor signaling pathway in which the signal is transmitted via the inhibition of adenylyl cyclase activity and a subsequent decrease in the intracellular concentration of cyclic AMP (cAMP). [GOC:dph, GOC:mah, GOC:signaling, GOC:tb, ISBN:0815316194]
GO:0007224 smoothened signaling pathway biological_process The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened. [GOC:mah, PMID:15057936, PMID:15205520]
GO:0021940 positive regulation of cerebellar granule cell precursor proliferation biological_process The process that activates or increases the rate or extent of granule cell precursor proliferation. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725]
GO:0034614 cellular response to reactive oxygen species biological_process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. [GOC:mah]
GO:0043410 positive regulation of MAPK cascade biological_process Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade. [GOC:go_curators]
GO:0045665 negative regulation of neuron differentiation biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation. [GOC:go_curators]
GO:0045879 negative regulation of smoothened signaling pathway biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling. [GOC:go_curators]
GO:0048712 negative regulation of astrocyte differentiation biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation. [GOC:vp, PMID:15139015]
GO:0060020 Bergmann glial cell differentiation biological_process The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate. [GOC:dph, PMID:10375501]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0016020 membrane cellular_component A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194]
GO:0060170 ciliary membrane cellular_component The portion of the plasma membrane surrounding a cilium. [GOC:cilia, GOC:dph, GOC:rph]
GO:0043235 receptor complex cellular_component Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. [GOC:go_curators]