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HAPLN2-201 ,HAPLN2 ,Q9GZV7
  • Uniprot Accession= Q9GZV7
  • Ensembl Transcript= ENST00000255039.6
  • Uniprot Name= HAPLN2
  • Name= Hyaluronan and proteoglycan link protein 2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 14
GO term GO name GO namespace GO def
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0005540 hyaluronic acid binding molecular_function Binding to hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. [GOC:jl]
GO:0007155 cell adhesion biological_process The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. [GOC:hb, GOC:pf]
GO:0008065 establishment of blood-nerve barrier biological_process The establishment of the barrier between the perineurium of peripheral nerves and the vascular endothelium of endoneurial capillaries. The perineurium acts as a diffusion barrier, but ion permeability at the blood-nerve barrier is still higher than at the blood-brain barrier. [GOC:dgh]
GO:0085029 extracellular matrix assembly biological_process The aggregation, arrangement and bonding together of the extracellular matrix. [GOC:jl]
GO:0031012 extracellular matrix cellular_component A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues. [GOC:BHF, GOC:mah, GOC:rph, NIF_Subcellular:nlx_subcell_20090513, PMID:21123617, PMID:28089324]
GO:0033268 node of Ranvier cellular_component An axon part that is a gap in the myelin where voltage-gated sodium channels cluster and saltatory conduction is executed. [GOC:mh]
GO:0010001 glial cell differentiation biological_process The process in which a relatively unspecialized cell acquires the specialized features of a glial cell. [GOC:go_curators, GOC:mtg_sensu]
GO:0005615 extracellular space cellular_component That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [ISBN:0198547684]
GO:0072534 perineuronal net cellular_component A dense extracellular matrix (ECM) that forms around many neuronal cell bodies and dendrites late in development and is responsible for synaptic stabilization in the adult brain. [GOC:sl, PMID:18364019]
GO:0002052 positive regulation of neuroblast proliferation biological_process Any process that activates or increases the rate of neuroblast proliferation. [GOC:dph]
GO:0001501 skeletal system development biological_process The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton). [GOC:dph, GOC:jid, GOC:tb]
GO:0007417 central nervous system development biological_process The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. [GOC:bf, GOC:jid, ISBN:0582227089]
GO:0045202 synapse cellular_component The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. [GOC:aruk, ISBN:0198506732, PMID:24619342, PMID:29383328, PMID:31998110]