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HOOK1-201 ,HOOK1 ,Q9UJC3
  • Number of GO Term: 22
GO term GO name GO namespace GO def
GO:0030897 HOPS complex cellular_component A multimeric protein complex that associates with the vacuolar membrane, late endosomal (multivesicular body) and lysosomal membranes. HOPS is a tethering complex involved in vesicle fusion. [PMID:10944212, PMID:23645161]
GO:0003779 actin binding molecular_function Binding to monomeric or multimeric forms of actin, including actin filaments. [GOC:clt]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0042802 identical protein binding molecular_function Binding to an identical protein or proteins. [GOC:jl]
GO:0042803 protein homodimerization activity molecular_function Binding to an identical protein to form a homodimer. [GOC:jl]
GO:0007030 Golgi organization biological_process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus. [GOC:dph, GOC:jl, GOC:mah]
GO:0007032 endosome organization biological_process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes. [GOC:dph, GOC:jl, GOC:mah]
GO:0007040 lysosome organization biological_process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases. [GOC:mah]
GO:0008333 endosome to lysosome transport biological_process The directed movement of substances from endosomes to lysosomes. [GOC:ai, ISBN:0716731363]
GO:0015031 protein transport biological_process The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]
GO:0045022 early endosome to late endosome transport biological_process The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs. [ISBN:0815316194, PMID:29980602]
GO:1905198 manchette assembly biological_process The aggregation, arrangement and bonding together of a set of components to form a manchette. [GO_REF:0000079, GOC:krc, GOC:TermGenie, PMID:22319670, PMID:24440897, PMID:26792866]
GO:1905719 protein localization to perinuclear region of cytoplasm biological_process A process in which a protein is transported to, or maintained in, a location within the perinuclear region of the cytoplasm. [GO_REF:0000087, GOC:TermGenie, PMID:15177031]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0005829 cytosol cellular_component The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
GO:0005874 microtubule cellular_component Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. [ISBN:0879693568]
GO:0070695 FHF complex cellular_component A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex). [GOC:ab, GOC:mah, PMID:18799622]
GO:0030705 cytoskeleton-dependent intracellular transport biological_process The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell. [GOC:mah]
GO:0031122 cytoplasmic microtubule organization biological_process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell. [GOC:mah]
GO:0008017 microtubule binding molecular_function Binding to a microtubule, a filament composed of tubulin monomers. [GOC:krc]
GO:0051959 dynein light intermediate chain binding molecular_function Binding to a light intermediate chain of the dynein complex. [GOC:bf]
GO:0005813 centrosome cellular_component A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle. [GOC:mah, ISBN:0198547684]