GO term | GO name | GO namespace | GO def |
GO:0030897 | HOPS complex | cellular_component | A multimeric protein complex that associates with the vacuolar membrane, late endosomal (multivesicular body) and lysosomal membranes. HOPS is a tethering complex involved in vesicle fusion. [PMID:10944212, PMID:23645161] |
GO:0003779 | actin binding | molecular_function | Binding to monomeric or multimeric forms of actin, including actin filaments. [GOC:clt] |
GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
GO:0042802 | identical protein binding | molecular_function | Binding to an identical protein or proteins. [GOC:jl] |
GO:0042803 | protein homodimerization activity | molecular_function | Binding to an identical protein to form a homodimer. [GOC:jl] |
GO:0007030 | Golgi organization | biological_process | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus. [GOC:dph, GOC:jl, GOC:mah] |
GO:0007032 | endosome organization | biological_process | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes. [GOC:dph, GOC:jl, GOC:mah] |
GO:0007040 | lysosome organization | biological_process | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases. [GOC:mah] |
GO:0008333 | endosome to lysosome transport | biological_process | The directed movement of substances from endosomes to lysosomes. [GOC:ai, ISBN:0716731363] |
GO:0015031 | protein transport | biological_process | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai] |
GO:0045022 | early endosome to late endosome transport | biological_process | The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs. [ISBN:0815316194, PMID:29980602] |
GO:1905198 | manchette assembly | biological_process | The aggregation, arrangement and bonding together of a set of components to form a manchette. [GO_REF:0000079, GOC:krc, GOC:TermGenie, PMID:22319670, PMID:24440897, PMID:26792866] |
GO:1905719 | protein localization to perinuclear region of cytoplasm | biological_process | A process in which a protein is transported to, or maintained in, a location within the perinuclear region of the cytoplasm. [GO_REF:0000087, GOC:TermGenie, PMID:15177031] |
GO:0005737 | cytoplasm | cellular_component | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684] |
GO:0005829 | cytosol | cellular_component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |
GO:0005874 | microtubule | cellular_component | Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. [ISBN:0879693568] |
GO:0070695 | FHF complex | cellular_component | A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex). [GOC:ab, GOC:mah, PMID:18799622] |
GO:0030705 | cytoskeleton-dependent intracellular transport | biological_process | The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell. [GOC:mah] |
GO:0031122 | cytoplasmic microtubule organization | biological_process | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell. [GOC:mah] |
GO:0008017 | microtubule binding | molecular_function | Binding to a microtubule, a filament composed of tubulin monomers. [GOC:krc] |
GO:0051959 | dynein light intermediate chain binding | molecular_function | Binding to a light intermediate chain of the dynein complex. [GOC:bf] |
GO:0005813 | centrosome | cellular_component | A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle. [GOC:mah, ISBN:0198547684] |