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ICMT-201 ,ICMT ,O60725
  • Uniprot Accession= O60725
  • Ensembl Transcript= ENST00000343813.10
  • Uniprot Name= ICMT
  • Name= Protein-S-isoprenylcysteine O-methyltransferase
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 11
GO term GO name GO namespace GO def
GO:0003880 protein C-terminal carboxyl O-methyltransferase activity molecular_function Catalysis of the transfer of a methyl group to the oxygen atom of a carboxyl group at the C-terminal of a protein. [PMID:8428937]
GO:0004671 protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity molecular_function Catalysis of the reaction
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0006481 C-terminal protein methylation biological_process The methylation of the C-terminal amino acid of a protein. [GOC:ai]
GO:0006612 protein targeting to membrane biological_process The process of directing proteins towards a membrane, usually using signals contained within the protein. [GOC:curators]
GO:0036211 protein modification process biological_process The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). [GOC:bf, GOC:jl]
GO:0046498 S-adenosylhomocysteine metabolic process biological_process The chemical reactions and pathways involving S-adenosylhomocysteine; the L-enantiomer is formed from S-adenosylmethionine and is a strong inhibitor of S-adenosylmethionine-mediated methylation reactions. It can be cleaved to form adenosine and homocysteine. [ISBN:0198506732]
GO:0046499 S-adenosylmethioninamine metabolic process biological_process The chemical reactions and pathways involving S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt. [GOC:mah, MetaCyc:S-ADENOSYLMETHIONINAMINE]
GO:0005783 endoplasmic reticulum cellular_component The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). [ISBN:0198506732]
GO:0005789 endoplasmic reticulum membrane cellular_component The lipid bilayer surrounding the endoplasmic reticulum. [GOC:mah]
GO:0016020 membrane cellular_component A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194]