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ID3-201 ,ID3 ,Q02535
  • Uniprot Accession= Q02535
  • Ensembl Transcript= ENST00000374561.6
  • Uniprot Name= ID3
  • Name= DNA-binding protein inhibitor ID-3
  • Chromosome= chr1
  • Driver status= Census, Compendium
  • Number of GO Term: 30
GO term GO name GO namespace GO def
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0019904 protein domain specific binding molecular_function Binding to a specific domain of a protein. [GOC:go_curators]
GO:0043425 bHLH transcription factor binding molecular_function Binding to a basic Helix-Loop-Helix (bHLH) superfamily of transcription factors, important regulatory components in transcriptional networks of many developmental pathways. [PMID:9144210]
GO:0046983 protein dimerization activity molecular_function The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits. [ISBN:0198506732]
GO:0140416 transcription regulator inhibitor activity molecular_function A molecular function regulator that inhibits the activity of a transcription regulator via direct binding and/or post-translational modification. [PMID:10652346]
GO:1901707 leptomycin B binding molecular_function Binding to leptomycin B. [GOC:TermGenie]
GO:0000122 negative regulation of transcription by RNA polymerase II biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. [GOC:go_curators, GOC:txnOH]
GO:0001656 metanephros development biological_process The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. [GOC:bf, ISBN:0192800752]
GO:0006275 regulation of DNA replication biological_process Any process that modulates the frequency, rate or extent of DNA replication. [GOC:go_curators]
GO:0007417 central nervous system development biological_process The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. [GOC:bf, GOC:jid, ISBN:0582227089]
GO:0007507 heart development biological_process The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. [GOC:jid, UBERON:0000948]
GO:0007517 muscle organ development biological_process The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work. [GOC:jid, ISBN:0198506732]
GO:0010628 positive regulation of gene expression biological_process Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). [GOC:txnOH-2018]
GO:0010629 negative regulation of gene expression biological_process Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). [GOC:txnOH-2018]
GO:0030182 neuron differentiation biological_process The process in which a relatively unspecialized cell acquires specialized features of a neuron. [GOC:mah]
GO:0030855 epithelial cell differentiation biological_process The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium. [GOC:ecd, PMID:11839751]
GO:0030903 notochord development biological_process The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column. [GOC:dgh]
GO:0042476 odontogenesis biological_process The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food. [GOC:jl, GOC:mah]
GO:0043065 positive regulation of apoptotic process biological_process Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis]
GO:0043433 negative regulation of DNA-binding transcription factor activity biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription. [GOC:jl]
GO:0045662 negative regulation of myoblast differentiation biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. [CL:0000056, GOC:go_curators, GOC:mtg_muscle]
GO:0045668 negative regulation of osteoblast differentiation biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation. [GOC:go_curators]
GO:0045892 negative regulation of DNA-templated transcription biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. [GOC:go_curators, GOC:txnOH]
GO:0072750 cellular response to leptomycin B biological_process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus. [GOC:mah]
GO:0005654 nucleoplasm cellular_component That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0030154 cell differentiation biological_process The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. [ISBN:0198506732]
GO:0140110 transcription regulator activity molecular_function A molecular function that controls the rate, timing and/or magnitude of gene transcription. The function of transcriptional regulators is to modulate gene expression at the transcription step so that they are expressed in the right cell at the right time and in the right amount throughout the life of the cell and the organism. Genes are transcriptional units, and include bacterial operons. [GOC:pg, GOC:txnOH-2018, Wikipedia:Transcription_factor]
GO:0032922 circadian regulation of gene expression biological_process Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours. [GOC:mah]
GO:0005634 nucleus cellular_component A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]