| GO term | GO name | GO namespace | GO def |
| GO:1903659 | regulation of complement-dependent cytotoxicity | biological_process | Any process that modulates the frequency, rate or extent of complement-dependent cytotoxicity. [GO_REF:0000058, GOC:TermGenie, PMID:24280217] |
| GO:2000352 | negative regulation of endothelial cell apoptotic process | biological_process | Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process. [GOC:BHF, GOC:mah, GOC:mtg_apoptosis] |
| GO:0002639 | positive regulation of immunoglobulin production | biological_process | Any process that activates or increases the frequency, rate, or extent of immunoglobulin production. [GOC:add] |
| GO:1900100 | positive regulation of plasma cell differentiation | biological_process | Any process that activates or increases the frequency, rate or extent of plasma cell differentiation. [GOC:TermGenie] |
| GO:0002904 | positive regulation of B cell apoptotic process | biological_process | Any process that activates or increases the frequency, rate, or extent of B cell apoptotic process. [GOC:add, GOC:mtg_apoptosis] |
| GO:0010468 | regulation of gene expression | biological_process | Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). [GOC:txnOH-2018] |
| GO:0030889 | negative regulation of B cell proliferation | biological_process | Any process that stops, prevents or reduces the rate or extent of B cell proliferation. [GOC:mah] |
| GO:2000273 | positive regulation of signaling receptor activity | biological_process | Any process that activates or increases the frequency, rate or extent of signaling receptor activity. [GOC:obol] |
| GO:0005125 | cytokine activity | molecular_function | The activity of a soluble extracellular gene product that interacts with a receptor to effect a change in the activity of the receptor to control the survival, growth, differentiation and effector function of tissues and cells. [ISBN:0198599471, PMID:11530802] |
| GO:0005141 | interleukin-10 receptor binding | molecular_function | Binding to an interleukin-10 receptor. [GOC:ai] |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0008083 | growth factor activity | molecular_function | The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation. [ISBN:0815316194] |
| GO:0046983 | protein dimerization activity | molecular_function | The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits. [ISBN:0198506732] |
| GO:0001818 | negative regulation of cytokine production | biological_process | Any process that stops, prevents, or reduces the rate of production of a cytokine. [GOC:add, ISBN:0781735149] |
| GO:0001819 | positive regulation of cytokine production | biological_process | Any process that activates or increases the frequency, rate or extent of production of a cytokine. [GOC:add, ISBN:0781735149] |
| GO:0001938 | positive regulation of endothelial cell proliferation | biological_process | Any process that activates or increases the rate or extent of endothelial cell proliferation. [GOC:add] |
| GO:0002237 | response to molecule of bacterial origin | biological_process | Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin. [GOC:rl, GOC:sm] |
| GO:0002439 | chronic inflammatory response to antigenic stimulus | biological_process | A chronic inflammatory response to an antigenic stimulus. A chronic inflammatory response persists indefinitely during days, weeks, or months in the life of an individual. [GOC:add, ISBN:0781735149] |
| GO:0002719 | negative regulation of cytokine production involved in immune response | biological_process | Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response. [GOC:add] |
| GO:0002875 | negative regulation of chronic inflammatory response to antigenic stimulus | biological_process | Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus. [GOC:add] |
| GO:0007165 | signal transduction | biological_process | The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. [GOC:go_curators, GOC:mtg_signaling_feb11] |
| GO:0007253 | cytoplasmic sequestering of NF-kappaB | biological_process | The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus. [GOC:jl] |
| GO:0008285 | negative regulation of cell population proliferation | biological_process | Any process that stops, prevents or reduces the rate or extent of cell proliferation. [GOC:go_curators] |
| GO:0009410 | response to xenobiotic stimulus | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:jl, GOC:krc] |
| GO:0010507 | negative regulation of autophagy | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. [GOC:dph, GOC:tb] |
| GO:0014823 | response to activity | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus. [GOC:mtg_muscle] |
| GO:0014854 | response to inactivity | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inactivity stimulus. [GOC:mtg_muscle] |
| GO:0030097 | hemopoiesis | biological_process | The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates. [GOC:dgh, ISBN:0198506732] |
| GO:0030183 | B cell differentiation | biological_process | The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity. [GO_REF:0000022, GOC:mah] |
| GO:0030595 | leukocyte chemotaxis | biological_process | The movement of a leukocyte in response to an external stimulus. [GOC:add, GOC:jl] |
| GO:0030886 | negative regulation of myeloid dendritic cell activation | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid dendritic cell activation. [GOC:mah] |
| GO:0032687 | negative regulation of interferon-alpha production | biological_process | Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-alpha production. [GOC:mah, PMID:15546383] |
| GO:0032689 | negative regulation of type II interferon production | biological_process | Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon. [GOC:add, GOC:mah, PMID:15546383] |
| GO:0032692 | negative regulation of interleukin-1 production | biological_process | Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production. [GOC:mah] |
| GO:0032695 | negative regulation of interleukin-12 production | biological_process | Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production. [GOC:mah] |
| GO:0032701 | negative regulation of interleukin-18 production | biological_process | Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-18 production. [GOC:mah, PMID:23710316] |
| GO:0032715 | negative regulation of interleukin-6 production | biological_process | Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production. [GOC:mah] |
| GO:0032717 | negative regulation of interleukin-8 production | biological_process | Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 production. [GOC:mah] |
| GO:0032720 | negative regulation of tumor necrosis factor production | biological_process | Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production. [GOC:mah, PMID:10891884, PMID:15560120] |
| GO:0032868 | response to insulin | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. [GOC:mah, ISBN:0198506732] |
| GO:0034115 | negative regulation of heterotypic cell-cell adhesion | biological_process | Any process that stops, prevents, or reduces the frequency, rate, or extent of heterotypic cell-cell adhesion. [GOC:add] |
| GO:0034116 | positive regulation of heterotypic cell-cell adhesion | biological_process | Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion. [GOC:add] |
| GO:0034465 | response to carbon monoxide | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus. [GOC:ecd] |
| GO:0035729 | cellular response to hepatocyte growth factor stimulus | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus. [GOC:bf] |
| GO:0042092 | type 2 immune response | biological_process | An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects. [GOC:add, ISBN:0781735149, PMID:18000958, PMID:18007680, PMID:20065995, PMID:20200518] |
| GO:0042100 | B cell proliferation | biological_process | The expansion of a B cell population by cell division. Follows B cell activation. [GOC:jl] |
| GO:0042130 | negative regulation of T cell proliferation | biological_process | Any process that stops, prevents or reduces the rate or extent of T cell proliferation. [GOC:jl] |
| GO:0042742 | defense response to bacterium | biological_process | Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism. [GOC:jl] |
| GO:0042832 | defense response to protozoan | biological_process | Reactions triggered in response to the presence of a protozoan that act to protect the cell or organism. [GOC:jl] |
| GO:0043032 | positive regulation of macrophage activation | biological_process | Any process that stimulates, induces or increases the rate of macrophage activation. [GOC:jl] |
| GO:0043066 | negative regulation of apoptotic process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis] |
| GO:0045019 | negative regulation of nitric oxide biosynthetic process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide. [GOC:go_curators] |
| GO:0045191 | regulation of isotype switching | biological_process | Any process that modulates the frequency, rate or extent of isotype switching. [GOC:ai] |
| GO:0045347 | negative regulation of MHC class II biosynthetic process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II. [GOC:go_curators] |
| GO:0045348 | positive regulation of MHC class II biosynthetic process | biological_process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II. [GOC:go_curators] |
| GO:0045787 | positive regulation of cell cycle | biological_process | Any process that activates or increases the rate or extent of progression through the cell cycle. [GOC:go_curators] |
| GO:0045893 | positive regulation of DNA-templated transcription | biological_process | Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. [GOC:go_curators, GOC:txnOH] |
| GO:0045930 | negative regulation of mitotic cell cycle | biological_process | Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle. [GOC:dph, GOC:go_curators, GOC:tb] |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | biological_process | Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. [GOC:go_curators, GOC:txnOH] |
| GO:0046427 | positive regulation of receptor signaling pathway via JAK-STAT | biological_process | Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity. [GOC:bf] |
| GO:0050728 | negative regulation of inflammatory response | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response. [GOC:ai] |
| GO:0050807 | regulation of synapse organization | biological_process | Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). [GOC:ai, GOC:dph, GOC:tb] |
| GO:0051045 | negative regulation of membrane protein ectodomain proteolysis | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of membrane protein ectodomain proteolysis. [GOC:ai] |
| GO:0051091 | positive regulation of DNA-binding transcription factor activity | biological_process | Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription. [GOC:ai] |
| GO:0051384 | response to glucocorticoid | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. [GOC:ai, PMID:9884123] |
| GO:0060302 | negative regulation of cytokine activity | biological_process | Any process that decreases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells. [GOC:BHF, GOC:dph, GOC:tb] |
| GO:0060670 | branching involved in labyrinthine layer morphogenesis | biological_process | The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer. [GOC:dph, PMID:16916377] |
| GO:0071222 | cellular response to lipopolysaccharide | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria. [GOC:mah] |
| GO:0071392 | cellular response to estradiol stimulus | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen. [GOC:mah] |
| GO:0071650 | negative regulation of chemokine (C-C motif) ligand 5 production | biological_process | Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5. [GOC:mah] |
| GO:0072577 | endothelial cell apoptotic process | biological_process | Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. [CL:0000115, GOC:BHF, GOC:mah, GOC:mtg_apoptosis] |
| GO:0097421 | liver regeneration | biological_process | The regrowth of lost or destroyed liver. [GOC:gap, PMID:19447520] |
| GO:1902895 | positive regulation of miRNA transcription | biological_process | Any process that activates or increases the frequency, rate or extent of microRNA (miRNA) gene transcription. [GO_REF:0000058, GOC:dph, GOC:kmv, GOC:TermGenie, PMID:24699545] |
| GO:1903034 | regulation of response to wounding | biological_process | Any process that modulates the frequency, rate or extent of response to wounding. [GO_REF:0000058, GOC:kmv, GOC:TermGenie, PMID:19164535] |
| GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway | biological_process | Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway. [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:15790595] |
| GO:1903672 | positive regulation of sprouting angiogenesis | biological_process | Any process that activates or increases the frequency, rate or extent of sprouting angiogenesis. [GO_REF:0000058, GOC:TermGenie, PMID:16756958] |
| GO:1904706 | negative regulation of vascular associated smooth muscle cell proliferation | biological_process | Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation. [GO_REF:0000058, GOC:TermGenie, PMID:23246467] |
| GO:1904707 | positive regulation of vascular associated smooth muscle cell proliferation | biological_process | Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation. [GO_REF:0000058, GOC:TermGenie, PMID:23246467] |
| GO:0005576 | extracellular region | cellular_component | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. [GOC:go_curators] |
| GO:0005615 | extracellular space | cellular_component | That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [ISBN:0198547684] |