GO term | GO name | GO namespace | GO def |
GO:0005143 | interleukin-12 receptor binding | molecular_function | Binding to an interleukin-12 receptor. [GOC:ai] |
GO:0042019 | interleukin-23 binding | molecular_function | Binding to interleukin-23. [GOC:jl] |
GO:0042020 | interleukin-23 receptor activity | molecular_function | Combining with interleukin-23 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. [GOC:jl, GOC:signaling] |
GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
GO:0001916 | positive regulation of T cell mediated cytotoxicity | biological_process | Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity. [GOC:add, ISBN:0781735149] |
GO:0002230 | positive regulation of defense response to virus by host | biological_process | Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication. [GOC:add, GOC:dph, GOC:tb, ISBN:0781735149] |
GO:0002827 | positive regulation of T-helper 1 type immune response | biological_process | Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response. [GOC:add] |
GO:0006954 | inflammatory response | biological_process | The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. [GO_REF:0000022, ISBN:0198506732] |
GO:0010536 | positive regulation of activation of Janus kinase activity | biological_process | Any process that increases the frequency or rate of activation of JAK (Janus Activated Kinase) protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it. [GOC:dph, GOC:tb, PMID:9135582] |
GO:0032496 | response to lipopolysaccharide | biological_process | Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria. [GOC:add, ISBN:0721601464] |
GO:0032693 | negative regulation of interleukin-10 production | biological_process | Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-10 production. [GOC:mah] |
GO:0032725 | positive regulation of granulocyte macrophage colony-stimulating factor production | biological_process | Any process that activates or increases the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production. [GOC:mah] |
GO:0032729 | positive regulation of type II interferon production | biological_process | Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon. [GOC:add, GOC:mah, PMID:15546383] |
GO:0032735 | positive regulation of interleukin-12 production | biological_process | Any process that activates or increases the frequency, rate, or extent of interleukin-12 production. [GOC:mah] |
GO:0032740 | positive regulation of interleukin-17 production | biological_process | Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines. [GOC:add, GOC:mah, PMID:16482511] |
GO:0032819 | positive regulation of natural killer cell proliferation | biological_process | Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation. [GOC:mah] |
GO:0034341 | response to type II interferon | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon. [GOC:add, ISBN:0126896631, PMID:15546383] |
GO:0038155 | interleukin-23-mediated signaling pathway | biological_process | The series of molecular signals initiated by interleukin-23 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:nhn, GOC:signaling] |
GO:0042102 | positive regulation of T cell proliferation | biological_process | Any process that activates or increases the rate or extent of T cell proliferation. [GOC:ai] |
GO:0042104 | positive regulation of activated T cell proliferation | biological_process | Any process that activates or increases the rate or extent of activated T cell proliferation. [GOC:jl] |
GO:0042509 | regulation of tyrosine phosphorylation of STAT protein | biological_process | Any process that modulates the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein. [GOC:jl, PMID:11426647] |
GO:0042531 | positive regulation of tyrosine phosphorylation of STAT protein | biological_process | Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein. [GOC:jl, PMID:11426647] |
GO:0043382 | positive regulation of memory T cell differentiation | biological_process | Any process that activates or increases the frequency, rate or extent of memory T cell differentiation. [ISBN:0781735149] |
GO:0045672 | positive regulation of osteoclast differentiation | biological_process | Any process that activates or increases the frequency, rate or extent of osteoclast differentiation. [GOC:go_curators] |
GO:0050829 | defense response to Gram-negative bacterium | biological_process | Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism. [GOC:ai] |
GO:0051135 | positive regulation of NK T cell activation | biological_process | Any process that activates or increases the frequency, rate or extent of natural killer T cell activation. [ISBN:0781735149, PMID:12154375, PMID:9133426] |
GO:2000318 | positive regulation of T-helper 17 type immune response | biological_process | Any process that activates or increases the frequency, rate or extent of T-helper 17 type immune response. [GOC:BHF, GOC:mah] |
GO:2000330 | positive regulation of T-helper 17 cell lineage commitment | biological_process | Any process that activates or increases the frequency, rate or extent of T-helper 17 cell lineage commitment. [GOC:BHF, GOC:mah] |
GO:0005886 | plasma membrane | cellular_component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
GO:0043235 | receptor complex | cellular_component | Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. [GOC:go_curators] |
GO:0072536 | interleukin-23 receptor complex | cellular_component | A protein complex that binds interleukin-23 and that consists of, at a minimum, a dimeric interleukin and its two receptor subunits as well as optional additional kinase subunits. [GOC:BHF, GOC:mah, PMID:12023369] |
GO:0004896 | cytokine receptor activity | molecular_function | Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. [GOC:add, GOC:mah] |
GO:0019221 | cytokine-mediated signaling pathway | biological_process | The series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mah, GOC:signaling, PMID:19295629] |
GO:0009897 | external side of plasma membrane | cellular_component | The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface. [GOC:dos, GOC:tb] |
GO:0019955 | cytokine binding | molecular_function | Binding to a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity. [GOC:ai, GOC:bf, ISBN:0198599471] |