GO term | GO name | GO namespace | GO def |
GO:0005518 | collagen binding | molecular_function | Binding to collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). [GOC:ai, ISBN:0198506732] |
GO:0046872 | metal ion binding | molecular_function | Binding to a metal ion. [GOC:ai] |
GO:0098639 | collagen binding involved in cell-matrix adhesion | molecular_function | Any collagen binding that occurs as part of cell-matrix adhesion. [GOC:dos] |
GO:0007160 | cell-matrix adhesion | biological_process | The binding of a cell to the extracellular matrix via adhesion molecules. [GOC:hb] |
GO:0007229 | integrin-mediated signaling pathway | biological_process | The series of molecular signals initiated by an extracellular ligand binding to an integrin on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mah, GOC:signaling] |
GO:0005886 | plasma membrane | cellular_component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
GO:0034680 | integrin alpha10-beta1 complex | cellular_component | An integrin complex that comprises one alpha10 subunit and one beta1 subunit. [PMID:12297042] |
GO:0008305 | integrin complex | cellular_component | A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands. [PMID:17543136] |
GO:0033627 | cell adhesion mediated by integrin | biological_process | The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits. [GOC:add, PMID:12213832, PMID:14754902] |
GO:0005178 | integrin binding | molecular_function | Binding to an integrin. [GOC:ceb] |
GO:0098609 | cell-cell adhesion | biological_process | The attachment of one cell to another cell via adhesion molecules. [GOC:dos] |
GO:0009897 | external side of plasma membrane | cellular_component | The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface. [GOC:dos, GOC:tb] |