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KLHL21-201 ,KLHL21 ,Q9UJP4
  • Uniprot Accession= Q9UJP4
  • Ensembl Transcript= ENST00000377658.8
  • Uniprot Name= KLHL21
  • Name= Kelch-like protein 21
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 11
GO term GO name GO namespace GO def
GO:0004842 ubiquitin-protein transferase activity molecular_function Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y = Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages. [GOC:BioGRID, GOC:jh2, PMID:9635407]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0097602 cullin family protein binding molecular_function Binding to a member of the cullin family, hydrophobic proteins that act as scaffolds for ubiquitin ligases (E3). [GOC:ha, InterPro:IPR016158, PMID:18698375]
GO:0007049 cell cycle biological_process The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. [GOC:go_curators, GOC:mtg_cell_cycle]
GO:0016567 protein ubiquitination biological_process The process in which one or more ubiquitin groups are added to a protein. [GOC:ai]
GO:0032465 regulation of cytokinesis biological_process Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells. [GOC:mah]
GO:0035853 chromosome passenger complex localization to spindle midzone biological_process A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the spindle midzone. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap. [GOC:mah, GOC:vw, PMID:15296749]
GO:0051301 cell division biological_process The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. [GOC:di, GOC:go_curators, GOC:pr]
GO:0005827 polar microtubule cellular_component Any of the spindle microtubules that come from each pole and overlap at the spindle midzone. This interdigitating structure consisting of antiparallel microtubules is responsible for pushing the poles of the spindle apart. [ISBN:0815316194]
GO:0005829 cytosol cellular_component The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
GO:0031463 Cul3-RING ubiquitin ligase complex cellular_component A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a BTB-domain-containing protein. [PMID:15571813, PMID:15688063]