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KMO-204 ,KMO ,O15229
  • Uniprot Accession= O15229
  • Ensembl Transcript= ENST00000366559.9
  • Uniprot Name= KMO
  • Name= Kynurenine 3-monooxygenase
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 19
GO term
GO name
GO namespace
GO def
GO:0004502 kynurenine 3-monooxygenase activity molecular_function Catalysis of the reaction
GO:0016174 NAD(P)H oxidase H2O2-forming activity molecular_function Catalysis of the reaction
GO:0050660 flavin adenine dinucleotide binding molecular_function Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2. [GOC:ai, GOC:imk, ISBN:0198506732]
GO:0071949 FAD binding molecular_function Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. [GOC:mah]
GO:0006569 tryptophan catabolic process biological_process The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid. [ISBN:0198547684]
GO:0009651 response to salt stress biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. [GOC:jl]
GO:0019674 NAD metabolic process biological_process The chemical reactions and pathways involving nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid. [GOC:jl, ISBN:0618254153]
GO:0019805 quinolinate biosynthetic process biological_process The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid. [GOC:ai]
GO:0034276 kynurenic acid biosynthetic process biological_process The chemical reactions and pathways resulting in the formation of kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid. [GOC:mah]
GO:0034354 'de novo' NAD biosynthetic process from tryptophan biological_process The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH. [PMID:17161604]
GO:0043420 anthranilate metabolic process biological_process The chemical reactions and pathways involving anthranilate (2-aminobenzoate). [GOC:jl]
GO:0070189 kynurenine metabolic process biological_process The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine. [CHEBI:28683, GOC:mah, GOC:rph]
GO:0071222 cellular response to lipopolysaccharide biological_process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria. [GOC:mah]
GO:0071347 cellular response to interleukin-1 biological_process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus. [GOC:mah]
GO:0097052 L-kynurenine metabolic process biological_process The chemical reactions and pathways involving L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine). [GOC:yaf]
GO:1903296 positive regulation of glutamate secretion, neurotransmission biological_process Any process that activates or increases the frequency, rate or extent of glutamate secretion, where glutamate acts as a neurotransmitter. [GO_REF:0000058, GOC:TermGenie, PMID:16782817]
GO:0005615 extracellular space cellular_component That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [ISBN:0198547684]
GO:0005741 mitochondrial outer membrane cellular_component The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. [GOC:ai]
GO:0005829 cytosol cellular_component The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]