| GO term | GO name | GO namespace | GO def |
| GO:0035633 | maintenance of blood-brain barrier | biological_process | Maintaining the structure and function of the blood-brain barrier, thus ensuring specific regulated transport of substances (e.g. macromolecules, small molecules, ions) into the brain, and out of the brain into the blood circulation. [GOC:aruk, GOC:bc, GOC:bf, GOC:sl, PMID:20080302, PMID:30280653] |
| GO:0062023 | collagen-containing extracellular matrix | cellular_component | An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells. [GOC:BHF, GOC:rph, PMID:21123617] |
| GO:0005201 | extracellular matrix structural constituent | molecular_function | The action of a molecule that contributes to the structural integrity of the extracellular matrix. [GOC:mah] |
| GO:0030023 | extracellular matrix constituent conferring elasticity | molecular_function | A component of the extracellular matrix that enables the matrix to recoil after transient stretching. [GOC:mah, ISBN:0815316194] |
| GO:0007155 | cell adhesion | biological_process | The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. [GOC:hb, GOC:pf] |
| GO:0007492 | endoderm development | biological_process | The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues. [GOC:dph, GOC:tb] |
| GO:0016477 | cell migration | biological_process | The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. [GOC:cjm, GOC:dph, GOC:ems, GOC:pf, Wikipedia:Cell_migration] |
| GO:0022617 | extracellular matrix disassembly | biological_process | A process that results in the breakdown of the extracellular matrix. [GOC:jid] |
| GO:0031581 | hemidesmosome assembly | biological_process | Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina. [GOC:dgh, PMID:15983403] |
| GO:0034446 | substrate adhesion-dependent cell spreading | biological_process | The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate. [GOC:mah, GOC:pf, PMID:17050732] |
| GO:0045785 | positive regulation of cell adhesion | biological_process | Any process that activates or increases the frequency, rate or extent of cell adhesion. [GOC:go_curators] |
| GO:0050679 | positive regulation of epithelial cell proliferation | biological_process | Any process that activates or increases the rate or extent of epithelial cell proliferation. [GOC:ai] |
| GO:0051149 | positive regulation of muscle cell differentiation | biological_process | Any process that activates or increases the frequency, rate or extent of muscle cell differentiation. [CL:0000187, GOC:ai] |
| GO:0065003 | protein-containing complex assembly | biological_process | The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex. [GOC:jl] |
| GO:0110011 | regulation of basement membrane organization | biological_process | Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane. [GOC:ha, PMID:27404358] |
| GO:2001046 | positive regulation of integrin-mediated signaling pathway | biological_process | Any process that activates or increases the frequency, rate or extent of integrin-mediated signaling pathway. [GOC:obol] |
| GO:0005576 | extracellular region | cellular_component | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. [GOC:go_curators] |
| GO:0005604 | basement membrane | cellular_component | A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers. [ISBN:0198547684, PMID:22505934] |
| GO:0005615 | extracellular space | cellular_component | That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [ISBN:0198547684] |
| GO:0005788 | endoplasmic reticulum lumen | cellular_component | The volume enclosed by the membranes of the endoplasmic reticulum. [ISBN:0198547684] |
| GO:0070062 | extracellular exosome | cellular_component | A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894] |
| GO:0098637 | protein complex involved in cell-matrix adhesion | cellular_component | Any protein complex that is capable of carrying out some part of the process of cell-matrix adhesion. [GOC:dos] |
| GO:0005606 | laminin-1 complex | cellular_component | A laminin complex composed of alpha1, beta1 and gamma1 polypeptide chains. [GOC:jl, PMID:10842354] |
| GO:0043259 | laminin-10 complex | cellular_component | A laminin complex composed of alpha5, beta1 and gamma1 polypeptide chains. [GOC:jl, PMID:10842354] |
| GO:0043260 | laminin-11 complex | cellular_component | A laminin complex composed of alpha5, beta2 and gamma1 polypeptide chains. [GOC:jl, PMID:10842354] |