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MCOLN2-202 ,MCOLN2 ,Q8IZK6
  • Uniprot Accession= Q8IZK6
  • Ensembl Transcript= ENST00000370608.8
  • Uniprot Name= MCOLN2
  • Name= Mucolipin-2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 19
GO term GO name GO namespace GO def
GO:0005262 calcium channel activity molecular_function Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. [GOC:mtg_transport, GOC:pr, ISBN:0815340729]
GO:0042802 identical protein binding molecular_function Binding to an identical protein or proteins. [GOC:jl]
GO:0002250 adaptive immune response biological_process An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory). [GO_REF:0000022, GOC:add, ISBN:0781735149]
GO:0015031 protein transport biological_process The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]
GO:0019722 calcium-mediated signaling biological_process Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions. [GOC:signaling]
GO:0045087 innate immune response biological_process Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. [GO_REF:0000022, GOC:add, GOC:ebc, GOC:mtg_sensu]
GO:0070588 calcium ion transmembrane transport biological_process A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. [GOC:mah]
GO:0071639 positive regulation of monocyte chemotactic protein-1 production biological_process Any process that activates or increases the frequency, rate, or extent of production of monocyte chemotactic protein-1. [GOC:mah]
GO:0071642 positive regulation of macrophage inflammatory protein 1 alpha production biological_process Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha. [GOC:mah]
GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production biological_process Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5. [GOC:mah]
GO:1905517 macrophage migration biological_process The orderly movement of a macrophage from one site to another. [GO_REF:0000091, GOC:TermGenie, PMID:25749876]
GO:1990266 neutrophil migration biological_process The movement of a neutrophil within or between different tissues and organs of the body. [PMID:1826836]
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production biological_process Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production. [GOC:BHF, GOC:mah]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0031902 late endosome membrane cellular_component The lipid bilayer surrounding a late endosome. [GOC:pz]
GO:0055038 recycling endosome membrane cellular_component The lipid bilayer surrounding a recycling endosome. [GOC:jid, GOC:rph, PMID:10930469, PMID:15601896, PMID:16246101]
GO:0072345 NAADP-sensitive calcium-release channel activity molecular_function Enables the transmembrane transfer of a calcium ion by a channel that opens when nicotinic acid adenine dinucleotide phosphate (NAADP) has been bound by the channel complex or one of its constituent parts. [PMID:19387438, PMID:19557428]
GO:0005765 lysosomal membrane cellular_component The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. [GOC:ai]
GO:0016020 membrane cellular_component A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194]