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MEAF6-201 ,MEAF6 ,Q9HAF1
  • Uniprot Accession= Q9HAF1
  • Ensembl Transcript= ENST00000296214.10
  • Uniprot Name= MEAF6
  • Name= Chromatin modification-related protein MEAF6
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 25
GO term GO name GO namespace GO def
GO:0036408 histone H3K14 acetyltransferase activity molecular_function Catalysis of the reaction
GO:0043995 histone H4K5 acetyltransferase activity molecular_function Catalysis of the reaction
GO:0043996 histone H4K8 acetyltransferase activity molecular_function Catalysis of the reaction
GO:0043997 histone H4K12 acetyltransferase activity molecular_function Catalysis of the reaction
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0001558 regulation of cell growth biological_process Any process that modulates the frequency, rate, extent or direction of cell growth. [GOC:go_curators]
GO:0006275 regulation of DNA replication biological_process Any process that modulates the frequency, rate or extent of DNA replication. [GOC:go_curators]
GO:0006338 chromatin remodeling biological_process A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication. [GOC:jid, GOC:vw, PMID:12042764, PMID:12697820]
GO:0006355 regulation of DNA-templated transcription biological_process Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. [GOC:go_curators, GOC:txnOH]
GO:0042981 regulation of apoptotic process biological_process Any process that modulates the occurrence or rate of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis]
GO:0045893 positive regulation of DNA-templated transcription biological_process Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. [GOC:go_curators, GOC:txnOH]
GO:0050793 regulation of developmental process biological_process Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). [GOC:go_curators]
GO:0051726 regulation of cell cycle biological_process Any process that modulates the rate or extent of progression through the cell cycle. [GOC:ai, GOC:dph, GOC:tb]
GO:1903706 regulation of hemopoiesis biological_process Any process that modulates the frequency, rate or extent of hemopoiesis. [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20080761]
GO:1905168 positive regulation of double-strand break repair via homologous recombination biological_process Any process that activates or increases the frequency, rate or extent of double-strand break repair via homologous recombination. [GO_REF:0000058, GOC:TermGenie, PMID:12023299]
GO:2000278 regulation of DNA biosynthetic process biological_process Any process that modulates the frequency, rate or extent of DNA biosynthetic process. [GOC:obol]
GO:2000779 regulation of double-strand break repair biological_process Any process that modulates the frequency, rate or extent of double-strand break repair. [GOC:BHF]
GO:0000123 histone acetyltransferase complex cellular_component A protein complex that possesses histone acetyltransferase activity. [GOC:mah]
GO:0000776 kinetochore cellular_component A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. [GOC:elh]
GO:0000786 nucleosome cellular_component A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures. [GOC:elh]
GO:0005634 nucleus cellular_component A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]
GO:0005654 nucleoplasm cellular_component That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653]
GO:0005730 nucleolus cellular_component A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. [ISBN:0198506732]
GO:0035267 NuA4 histone acetyltransferase complex cellular_component A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60). [GOC:ecd, PMID:10966108, PMID:14966270]
GO:0070776 MOZ/MORF histone acetyltransferase complex cellular_component A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3. [PMID:18794358]