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MINDY1-207 ,MINDY1 ,Q8N5J2
  • Uniprot Accession= Q8N5J2
  • Ensembl Transcript= ENST00000683666.2
  • Uniprot Name= MINDY1
  • Name= Ubiquitin carboxyl-terminal hydrolase MINDY-1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 10
GO term GO name GO namespace GO def
GO:0004843 cysteine-type deubiquitinase activity molecular_function An thiol-dependent isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated. [GOC:jh2, PMID:30783221]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0016807 cysteine-type carboxypeptidase activity molecular_function Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CARBOXYPEPTIDASE]
GO:0036435 K48-linked polyubiquitin modification-dependent protein binding molecular_function Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 48 in the target protein. [GOC:al, PMID:20739285]
GO:1990380 K48-linked deubiquitinase activity molecular_function Hydrolysis of a ubiquitin unit from a ubiquitinated protein linked via the Lys48 residue of ubiquitin. [GOC:bf, GOC:PARL, PMID:22970133]
GO:0006508 proteolysis biological_process The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. [GOC:bf, GOC:mah]
GO:0008150 biological_process biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. [GOC:pdt]
GO:0005654 nucleoplasm cellular_component That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653]
GO:0016604 nuclear body cellular_component Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins. [GOC:ma, PMID:10330182]
GO:0071108 protein K48-linked deubiquitination biological_process A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein. [GOC:mah]