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MPC2-201 ,MPC2 ,O95563
  • Uniprot Accession= O95563
  • Ensembl Transcript= ENST00000271373.9
  • Uniprot Name= MPC2
  • Name= Mitochondrial pyruvate carrier 2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 10
GO term GO name GO namespace GO def
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0042802 identical protein binding molecular_function Binding to an identical protein or proteins. [GOC:jl]
GO:0006086 acetyl-CoA biosynthetic process from pyruvate biological_process The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate. [GOC:dph, GOC:go_curators, GOC:tb]
GO:0006850 mitochondrial pyruvate transmembrane transport biological_process The process in which pyruvate is transported across a mitochondrial membrane, into or out of the mitochondrion. [GOC:vw, PMID:22628558]
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus biological_process Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. [GOC:bf, GOC:yaf]
GO:0005634 nucleus cellular_component A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]
GO:0005739 mitochondrion cellular_component A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. [GOC:giardia, ISBN:0198506732]
GO:0005743 mitochondrial inner membrane cellular_component The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. [GOC:ai]
GO:0098800 inner mitochondrial membrane protein complex cellular_component Any protein complex that is part of the inner mitochondrial membrane. [GOC:dos]
GO:0050833 pyruvate transmembrane transporter activity molecular_function Enables the transfer of pyruvate, 2-oxopropanoate, from one side of a membrane to the other. [GOC:ai]