| GO term | GO name | GO namespace | GO def |
| GO:0031648 | protein destabilization | biological_process | Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation. [GOC:mah] |
| GO:0006468 | protein phosphorylation | biological_process | The process of introducing a phosphate group on to a protein. [GOC:hb] |
| GO:0016242 | negative regulation of macroautophagy | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy. [GOC:go_curators] |
| GO:0016310 | phosphorylation | biological_process | The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. [ISBN:0198506732] |
| GO:0046777 | protein autophosphorylation | biological_process | The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation). [ISBN:0198506732] |
| GO:0016605 | PML body | cellular_component | A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection. [GOC:ma, PMID:10944585] |
| GO:0001002 | RNA polymerase III type 1 promoter sequence-specific DNA binding | molecular_function | Binding to a sequence of DNA that is a part of a type 1 promoter that controls transcription by RNA polymerase III. Type 1 promoters are found in 5S rRNA genes, downstream of the transcription start site within the sequence of the mature RNA, and require TFIIIA for recognition. [GOC:txnOH, PMID:12381659] |
| GO:0001003 | RNA polymerase III type 2 promoter sequence-specific DNA binding | molecular_function | Binding to a sequence of DNA that is a part of a type 2 promoter that controls transcription by RNA polymerase III. Type 2 promoters consist of an A box and a B box downstream of the transcription start site within the sequence within the sequence of the mature RNA. Type 2 promoters are found in many tRNA genes as well as in other small RNAs. [GOC:txnOH, PMID:12381659] |
| GO:0001006 | RNA polymerase III type 3 promoter sequence-specific DNA binding | molecular_function | Binding to a sequence of DNA that is a part of a type 3 promoter that controls transcription by RNA polymerase III (Pol III). A type 3 Pol III promoter is composed of elements upstream of the transcription start site, including a TATA box. The human U6 snRNA gene has a type 3 promoter. Type 3 Pol III promoters have not been observed in S. cerevisiae. [GOC:txnOH, PMID:12381659] |
| GO:0001156 | TFIIIC-class transcription factor complex binding | molecular_function | Binding to a general RNA polymerase III transcription factor belonging to the TFIIC complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III. [GOC:txnOH, PMID:12381659] |
| GO:0004672 | protein kinase activity | molecular_function | Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction |
| GO:0004674 | protein serine/threonine kinase activity | molecular_function | Catalysis of the reactions |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0005524 | ATP binding | molecular_function | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. [ISBN:0198506732] |
| GO:0016301 | kinase activity | molecular_function | Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. [ISBN:0198506732] |
| GO:0042802 | identical protein binding | molecular_function | Binding to an identical protein or proteins. [GOC:jl] |
| GO:0043022 | ribosome binding | molecular_function | Binding to a ribosome. [GOC:go_curators] |
| GO:0051219 | phosphoprotein binding | molecular_function | Binding to a phosphorylated protein. [GOC:ai] |
| GO:0106310 | protein serine kinase activity | molecular_function | Catalysis of the reactions |
| GO:0001558 | regulation of cell growth | biological_process | Any process that modulates the frequency, rate, extent or direction of cell growth. [GOC:go_curators] |
| GO:0002296 | T-helper 1 cell lineage commitment | biological_process | The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 1 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis. [GOC:add, ISBN:0781735149] |
| GO:0003007 | heart morphogenesis | biological_process | The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. [GOC:dph, GOC:isa_complete] |
| GO:0003179 | heart valve morphogenesis | biological_process | The process in which the structure of a heart valve is generated and organized. [GOC:mtg_heart] |
| GO:0006112 | energy reserve metabolic process | biological_process | The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen. [GOC:mah] |
| GO:0006207 | 'de novo' pyrimidine nucleobase biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors. [GOC:mah, ISBN:0716720094] |
| GO:0006954 | inflammatory response | biological_process | The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. [GO_REF:0000022, ISBN:0198506732] |
| GO:0006974 | DNA damage response | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. [GOC:go_curators] |
| GO:0007010 | cytoskeleton organization | biological_process | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures. [GOC:dph, GOC:jl, GOC:mah] |
| GO:0007040 | lysosome organization | biological_process | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases. [GOC:mah] |
| GO:0007281 | germ cell development | biological_process | The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism. [GOC:go_curators] |
| GO:0007584 | response to nutrient | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus. [GOC:go_curators] |
| GO:0008361 | regulation of cell size | biological_process | Any process that modulates the size of a cell. [GOC:go_curators] |
| GO:0009267 | cellular response to starvation | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment. [GOC:jl] |
| GO:0009408 | response to heat | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. [GOC:lr] |
| GO:0009791 | post-embryonic development | biological_process | The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development. [GOC:go_curators] |
| GO:0010507 | negative regulation of autophagy | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. [GOC:dph, GOC:tb] |
| GO:0010592 | positive regulation of lamellipodium assembly | biological_process | Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell. [GOC:dph, GOC:tb] |
| GO:0010628 | positive regulation of gene expression | biological_process | Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). [GOC:txnOH-2018] |
| GO:0010718 | positive regulation of epithelial to mesenchymal transition | biological_process | Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. [GOC:BHF, GOC:dph, GOC:tb] |
| GO:0010831 | positive regulation of myotube differentiation | biological_process | Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. [GOC:dph, GOC:tb] |
| GO:0016236 | macroautophagy | biological_process | The autophagic process that proceeds via the formation of an autophagosome. [PMID:24366339] |
| GO:0016241 | regulation of macroautophagy | biological_process | Any process that modulates the frequency, rate or extent of macroautophagy. [GOC:krc] |
| GO:0018105 | peptidyl-serine phosphorylation | biological_process | The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine. [RESID:AA0037] |
| GO:0019228 | neuronal action potential | biological_process | An action potential that occurs in a neuron. [GOC:dph, GOC:isa_complete, GOC:tb] |
| GO:0030163 | protein catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. [GOC:mah] |
| GO:0030307 | positive regulation of cell growth | biological_process | Any process that activates or increases the frequency, rate, extent or direction of cell growth. [GOC:go_curators] |
| GO:0030838 | positive regulation of actin filament polymerization | biological_process | Any process that activates or increases the frequency, rate or extent of actin polymerization. [GOC:mah] |
| GO:0031295 | T cell costimulation | biological_process | The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation. [ISBN:0781735149] |
| GO:0031529 | ruffle organization | biological_process | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell. [GOC:mah, PMID:10036235] |
| GO:0031641 | regulation of myelination | biological_process | Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons. [GOC:mah] |
| GO:0031667 | response to nutrient levels | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients. [GOC:mah] |
| GO:0031669 | cellular response to nutrient levels | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients. [GOC:mah] |
| GO:0031670 | cellular response to nutrient | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus. [GOC:mah] |
| GO:0031929 | TOR signaling | biological_process | The series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors. [PMID:12372295] |
| GO:0032516 | positive regulation of phosphoprotein phosphatase activity | biological_process | Any process that activates or increases the activity of a phosphoprotein phosphatase. [GOC:mah] |
| GO:0032869 | cellular response to insulin stimulus | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. [GOC:mah, ISBN:0198506732] |
| GO:0032956 | regulation of actin cytoskeleton organization | biological_process | Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. [GOC:mah] |
| GO:0033173 | calcineurin-NFAT signaling cascade | biological_process | Any intracellular signal transduction in which the signal is passed on within the cell by activation of a member of the NFAT protein family as a consequence of NFAT dephosphorylation by Ca(2+)-activated calcineurin. The cascade begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin dephosphorylates multiple phosphoserine residues on NFAT, resulting in the translocation of NFAT to the nucleus. The cascade ends with regulation of transcription by NFAT. The calcineurin-NFAT cascade lies downstream of many cell surface receptors, including G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs) that signal to mobilize calcium ions (Ca2+). [GOC:lm, GOC:mah, PMID:12975316, PMID:15928679] |
| GO:0034198 | cellular response to amino acid starvation | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids. [GOC:ecd] |
| GO:0035264 | multicellular organism growth | biological_process | The increase in size or mass of an entire multicellular organism, as opposed to cell growth. [GOC:bf, GOC:curators, GOC:dph, GOC:tb] |
| GO:0038202 | TORC1 signaling | biological_process | A series of intracellular molecular signals mediated by TORC1; TOR (target of rapamycin) in complex with at least Raptor (regulatory-associated protein of TOR), or orthologs of, and other signaling components. [GOC:lb] |
| GO:0042752 | regulation of circadian rhythm | biological_process | Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours. [GOC:dph, GOC:jl, GOC:tb] |
| GO:0043066 | negative regulation of apoptotic process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis] |
| GO:0043200 | response to amino acid | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. [GOC:ef, GOC:mlg] |
| GO:0043276 | anoikis | biological_process | Apoptosis triggered by inadequate or inappropriate adherence to substrate e.g. after disruption of the interactions between normal epithelial cells and the extracellular matrix. [GOC:jl, http://www.copewithcytokines.de/] |
| GO:0045670 | regulation of osteoclast differentiation | biological_process | Any process that modulates the frequency, rate or extent of osteoclast differentiation. [GOC:go_curators] |
| GO:0045727 | positive regulation of translation | biological_process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. [GOC:dph, GOC:go_curators, GOC:tb] |
| GO:0045792 | negative regulation of cell size | biological_process | Any process that reduces cell size. [GOC:go_curators] |
| GO:0045821 | positive regulation of glycolytic process | biological_process | Any process that activates or increases the frequency, rate or extent of glycolysis. [GOC:go_curators] |
| GO:0045945 | positive regulation of transcription by RNA polymerase III | biological_process | Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase III. [GOC:go_curators, GOC:txnOH] |
| GO:0045948 | positive regulation of translational initiation | biological_process | Any process that activates or increases the frequency, rate or extent of translational initiation. [GOC:go_curators] |
| GO:0046889 | positive regulation of lipid biosynthetic process | biological_process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. [GOC:ai] |
| GO:0048266 | behavioral response to pain | biological_process | Any process that results in a change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli. [GOC:jid] |
| GO:0048511 | rhythmic process | biological_process | Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism. [GOC:jid] |
| GO:0048709 | oligodendrocyte differentiation | biological_process | The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system. [GOC:vp, PMID:15139015] |
| GO:0048714 | positive regulation of oligodendrocyte differentiation | biological_process | Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation. [GOC:vp, PMID:15139015] |
| GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | biological_process | Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine. [GOC:ai] |
| GO:0050882 | voluntary musculoskeletal movement | biological_process | The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system that can be controlled at will. [GOC:dph] |
| GO:0051496 | positive regulation of stress fiber assembly | biological_process | Any process that activates or increases the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts. [GOC:ai] |
| GO:0051549 | positive regulation of keratinocyte migration | biological_process | Any process that activates or increases the frequency, rate or extent of keratinocyte migration. [GOC:ai] |
| GO:0051647 | nucleus localization | biological_process | Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell. [GOC:ai] |
| GO:0051897 | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | biological_process | Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase/protein kinase B signal transduction. [GOC:ai] |
| GO:0055013 | cardiac muscle cell development | biological_process | The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state. [GOC:devbiol, GOC:mtg_heart] |
| GO:0060048 | cardiac muscle contraction | biological_process | Muscle contraction of cardiac muscle tissue. [GOC:dph] |
| GO:0070885 | negative regulation of calcineurin-NFAT signaling cascade | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of the calcineurin-NFAT signaling cascade. [GOC:mah] |
| GO:0071230 | cellular response to amino acid stimulus | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. [GOC:mah] |
| GO:0071233 | cellular response to leucine | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus. [GOC:mah] |
| GO:0071456 | cellular response to hypoxia | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. [GOC:mah] |
| GO:0071470 | cellular response to osmotic stress | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. [GOC:mah] |
| GO:0090559 | regulation of membrane permeability | biological_process | Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by a membrane. [GOC:kmv, PMID:22677064] |
| GO:1900034 | regulation of cellular response to heat | biological_process | Any process that modulates the frequency, rate or extent of cellular response to heat. [GOC:TermGenie, GOC:yaf] |
| GO:1900181 | negative regulation of protein localization to nucleus | biological_process | Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus. [GOC:TermGenie] |
| GO:1901796 | regulation of signal transduction by p53 class mediator | biological_process | Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator. [GOC:TermGenie] |
| GO:1901838 | positive regulation of transcription of nucleolar large rRNA by RNA polymerase I | biological_process | Any process that activates or increases the frequency, rate or extent of transcription of nuclear large rRNA mediated by RNA polymerase I. [GOC:sart, GOC:TermGenie] |
| GO:1903691 | positive regulation of wound healing, spreading of epidermal cells | biological_process | Any process that activates or increases the frequency, rate or extent of wound healing, spreading of epidermal cells. [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:18394891] |
| GO:1904059 | regulation of locomotor rhythm | biological_process | Any process that modulates the frequency, rate or extent of locomotor rhythm. [GO_REF:0000058, GOC:TermGenie, PMID:16310969] |
| GO:1904690 | positive regulation of cytoplasmic translational initiation | biological_process | Any process that activates or increases the frequency, rate or extent of cytoplasmic translational initiation. [GO_REF:0000058, GOC:TermGenie, PMID:12242291] |
| GO:1905672 | negative regulation of lysosome organization | biological_process | Any process that stops, prevents or reduces the frequency, rate or extent of lysosome organization. [GO_REF:0000058, GOC:TermGenie, PMID:25561470] |
| GO:1905857 | positive regulation of pentose-phosphate shunt | biological_process | Any process that activates or increases the frequency, rate or extent of pentose-phosphate shunt. [GO_REF:0000058, GOC:TermGenie, PMID:19015259] |
| GO:1990253 | cellular response to leucine starvation | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine. [PMID:19033384] |
| GO:2000785 | regulation of autophagosome assembly | biological_process | Any process that modulates the frequency, rate or extent of autophagosome assembly. [GOC:autophagy, GOC:BHF] |
| GO:0005765 | lysosomal membrane | cellular_component | The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. [GOC:ai] |
| GO:0005829 | cytosol | cellular_component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |
| GO:0000139 | Golgi membrane | cellular_component | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. [GOC:mah] |
| GO:0005654 | nucleoplasm | cellular_component | That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653] |
| GO:0005737 | cytoplasm | cellular_component | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684] |
| GO:0005741 | mitochondrial outer membrane | cellular_component | The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. [GOC:ai] |
| GO:0005764 | lysosome | cellular_component | A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions. [GOC:mah, ISBN:0198506732] |
| GO:0005789 | endoplasmic reticulum membrane | cellular_component | The lipid bilayer surrounding the endoplasmic reticulum. [GOC:mah] |
| GO:0012505 | endomembrane system | cellular_component | A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. [GOC:lh] |
| GO:0016020 | membrane | cellular_component | A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194] |
| GO:0030425 | dendrite | cellular_component | A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body. [GOC:aruk, GOC:bc, GOC:dos, GOC:mah, GOC:nln, ISBN:0198506732] |
| GO:0031931 | TORC1 complex | cellular_component | A protein complex that contains at least TOR (target of rapamycin) and Raptor (regulatory-associated protein of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of S6K. In Saccharomyces, the complex contains Kog1p, Lst8p, Tco89p, and either Tor1p or Tor2p. [GOC:jh, PMID:15780592, PMID:16469695, PMID:21548787] |
| GO:0031932 | TORC2 complex | cellular_component | A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p. [GOC:bf, GOC:jh, PMID:14736892, PMID:15780592, PMID:16469695, PMID:21548787] |
| GO:0045335 | phagocytic vesicle | cellular_component | A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis. [GOC:go_curators, ISBN:0198506732] |
| GO:0005635 | nuclear envelope | cellular_component | The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space). [ISBN:0198547684] |
| GO:0005634 | nucleus | cellular_component | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators] |