| GO term | GO name | GO namespace | GO def |
| GO:0002039 | p53 binding | molecular_function | Binding to one of the p53 family of proteins. [GOC:hjd] |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0019789 | SUMO transferase activity | molecular_function | Catalysis of the transfer of SUMO from one protein to another via the reaction X-SUMO + Y = Y-SUMO + X, where both X-SUMO and Y-SUMO are covalent linkages. [GOC:rn, PMID:11031248, PMID:11265250] |
| GO:0031625 | ubiquitin protein ligase binding | molecular_function | Binding to a ubiquitin protein ligase enzyme, any of the E3 proteins. [GOC:vp] |
| GO:0042802 | identical protein binding | molecular_function | Binding to an identical protein or proteins. [GOC:jl] |
| GO:0046872 | metal ion binding | molecular_function | Binding to a metal ion. [GOC:ai] |
| GO:0061630 | ubiquitin protein ligase activity | molecular_function | Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S = X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond |
| GO:0000209 | protein polyubiquitination | biological_process | Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain. [ISBN:0815316194] |
| GO:0000266 | mitochondrial fission | biological_process | The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. [PMID:11038192] |
| GO:0006915 | apoptotic process | biological_process | A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. [GOC:cjm, GOC:dhl, GOC:ecd, GOC:go_curators, GOC:mtg_apoptosis, GOC:tb, ISBN:0198506732, PMID:18846107, PMID:21494263] |
| GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process | biological_process | Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process. [GOC:al, GOC:dph, GOC:jl, GOC:mtg_apoptosis, GOC:tb, PMID:14744432, PMID:18328827, Wikipedia:Caspase] |
| GO:0010637 | negative regulation of mitochondrial fusion | biological_process | Any process that decreases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. [GOC:dph, GOC:tb] |
| GO:0010821 | regulation of mitochondrion organization | biological_process | Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion. [GOC:dph, GOC:tb] |
| GO:0016567 | protein ubiquitination | biological_process | The process in which one or more ubiquitin groups are added to a protein. [GOC:ai] |
| GO:0016925 | protein sumoylation | biological_process | The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein. [GOC:jl, PMID:11265250] |
| GO:0030308 | negative regulation of cell growth | biological_process | Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth. [GOC:go_curators] |
| GO:0031648 | protein destabilization | biological_process | Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation. [GOC:mah] |
| GO:0033235 | positive regulation of protein sumoylation | biological_process | Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein. [GOC:mah] |
| GO:0043123 | positive regulation of canonical NF-kappaB signal transduction | biological_process | Any process that activates or increases the frequency, rate or extent of a canonical NF-kappaB signaling cascade. [GOC:jl] |
| GO:0045824 | negative regulation of innate immune response | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response. [GOC:go_curators] |
| GO:0050689 | negative regulation of defense response to virus by host | biological_process | Any host process that results in the inhibition of antiviral immune response mechanisms, thereby facilitating viral replication. The host is defined as the larger of the organisms involved in a symbiotic interaction. [GOC:ai, GOC:dph, GOC:tb] |
| GO:0050821 | protein stabilization | biological_process | Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation. [GOC:ai] |
| GO:0051646 | mitochondrion localization | biological_process | Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell. [GOC:ai] |
| GO:0051881 | regulation of mitochondrial membrane potential | biological_process | Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. [GOC:ai] |
| GO:0051898 | negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylinositol 3-kinase/protein kinase B signal transduction. [GOC:ai] |
| GO:0060339 | negative regulation of type I interferon-mediated signaling pathway | biological_process | Any process that decreases the rate, frequency or extent of a type I interferon-mediated signaling pathway. [GOC:dph] |
| GO:0071360 | cellular response to exogenous dsRNA | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus. [GOC:mah] |
| GO:0071650 | negative regulation of chemokine (C-C motif) ligand 5 production | biological_process | Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5. [GOC:mah] |
| GO:0090141 | positive regulation of mitochondrial fission | biological_process | Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. [GOC:ascb_2009, GOC:dph, GOC:tb] |
| GO:1901028 | regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | biological_process | Any process that modulates the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. [GOC:BHF, GOC:mtg_apoptosis, GOC:TermGenie] |
| GO:1903861 | positive regulation of dendrite extension | biological_process | Any process that activates or increases the frequency, rate or extent of dendrite extension. [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:24898855] |
| GO:1904925 | positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization | biological_process | Any process that activates or increases the frequency, rate or extent of autophagy of the mitochondrion in response to mitochondrial depolarization. [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:22020285] |
| GO:0005739 | mitochondrion | cellular_component | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. [GOC:giardia, ISBN:0198506732] |
| GO:0005741 | mitochondrial outer membrane | cellular_component | The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. [GOC:ai] |
| GO:0005777 | peroxisome | cellular_component | A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism. [GOC:pm, PMID:9302272, UniProtKB-KW:KW-0576] |
| GO:0016020 | membrane | cellular_component | A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194] |
| GO:0030424 | axon | cellular_component | The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. [GOC:nln, ISBN:0198506732] |
| GO:0043025 | neuronal cell body | cellular_component | The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites. [GOC:go_curators] |
| GO:0004842 | ubiquitin-protein transferase activity | molecular_function | Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y = Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages. [GOC:BioGRID, GOC:jh2, PMID:9635407] |