| GO term | GO name | GO namespace | GO def |
| GO:0003674 | molecular_function | molecular_function | A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. [GOC:pdt] |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0019215 | intermediate filament binding | molecular_function | Binding to an intermediate filament, a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. [ISBN:0198506732] |
| GO:0000086 | G2/M transition of mitotic cell cycle | biological_process | The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex. [GOC:mtg_cell_cycle] |
| GO:0007417 | central nervous system development | biological_process | The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. [GOC:bf, GOC:jid, ISBN:0582227089] |
| GO:0007420 | brain development | biological_process | The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). [GOC:dph, GOC:jid, GOC:tb, UBERON:0000955] |
| GO:0030844 | positive regulation of intermediate filament depolymerization | biological_process | Any process that activates or increases the frequency, rate or extent of intermediate filament depolymerization. [GOC:mah] |
| GO:0031076 | embryonic camera-type eye development | biological_process | The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure. [GOC:mah, GOC:mtg_sensu] |
| GO:0032091 | negative regulation of protein binding | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding. [GOC:mah] |
| GO:0043086 | negative regulation of catalytic activity | biological_process | Any process that stops or reduces the activity of an enzyme. [GOC:ebc, GOC:jl, GOC:tb, GOC:vw] |
| GO:0043524 | negative regulation of neuron apoptotic process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons. [GOC:go_curators, GOC:mtg_apoptosis] |
| GO:0048858 | cell projection morphogenesis | biological_process | The process in which the anatomical structures of a cell projection are generated and organized. [GO_REF:0000021] |
| GO:0051402 | neuron apoptotic process | biological_process | Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. [CL:0000540, GOC:mtg_apoptosis] |
| GO:0072089 | stem cell proliferation | biological_process | The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. [GOC:mtg_kidney_jan10] |
| GO:2000179 | positive regulation of neural precursor cell proliferation | biological_process | Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation. [GOC:dph, GOC:yaf] |
| GO:0005737 | cytoplasm | cellular_component | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684] |
| GO:0005882 | intermediate filament | cellular_component | A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes |
| GO:0045111 | intermediate filament cytoskeleton | cellular_component | Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell. [ISBN:0716731363] |
| GO:0031730 | CCR5 chemokine receptor binding | molecular_function | Binding to a CCR5 chemokine receptor. [GOC:mah, GOC:nln] |