GO term | GO name | GO namespace | GO def |
GO:0005901 | caveola | cellular_component | A membrane raft that forms small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane. Examples include flask-shaped invaginations of the plasma membrane in adipocytes associated with caveolin proteins, and minute pits or incuppings of the cell membrane formed during pinocytosis. Caveolae may be pinched off to form free vesicles within the cytoplasm. [GOC:mah, ISBN:0721662544, PMID:16645198] |
GO:0030315 | T-tubule | cellular_component | Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane. [GOC:mtg_muscle, ISBN:0815316194] |
GO:0031965 | nuclear membrane | cellular_component | Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. [GOC:mah, GOC:pz] |
GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
GO:0035591 | signaling adaptor activity | molecular_function | The binding activity of a molecule that brings together two or more molecules in a signaling pathway, permitting those molecules to function in a coordinated way. Adaptor molecules themselves do not have catalytic activity. [GOC:bf, PMID:19104498] |
GO:0003062 | regulation of heart rate by chemical signal | biological_process | The regulation of the rate of heart contraction mediated by chemical signaling, hormonal, autocrine or paracrine. [GOC:dph, GOC:mtg_cardio, GOC:rl, GOC:tb] |
GO:0010628 | positive regulation of gene expression | biological_process | Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). [GOC:txnOH-2018] |
GO:0010750 | positive regulation of nitric oxide mediated signal transduction | biological_process | Any process that increases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is The series of molecular signals mediated by the detection of nitric oxide (NO). [GOC:BHF, GOC:dph, GOC:tb] |
GO:0045428 | regulation of nitric oxide biosynthetic process | biological_process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide. [GOC:go_curators] |
GO:0045429 | positive regulation of nitric oxide biosynthetic process | biological_process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide. [GOC:go_curators] |
GO:0050999 | regulation of nitric-oxide synthase activity | biological_process | Any process that modulates the activity of the enzyme nitric-oxide synthase. [GOC:ai] |
GO:0051000 | positive regulation of nitric-oxide synthase activity | biological_process | Any process that activates or increases the activity of the enzyme nitric-oxide synthase. [GOC:ai] |
GO:0060307 | regulation of ventricular cardiac muscle cell membrane repolarization | biological_process | Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in a ventricular cardiomyocyte. [GOC:BHF, GOC:dph, GOC:mtg_cardiac_conduct_nov11, GOC:tb] |
GO:0098901 | regulation of cardiac muscle cell action potential | biological_process | Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. [GOC:dos, GOC:mtg_cardiac_conduct_nov11] |
GO:0098974 | postsynaptic actin cytoskeleton organization | biological_process | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton. [GOC:dos] |
GO:1901381 | positive regulation of potassium ion transmembrane transport | biological_process | Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transport. [GOC:BHF, GOC:TermGenie] |
GO:1901841 | regulation of high voltage-gated calcium channel activity | biological_process | Any process that modulates the frequency, rate or extent of high voltage-gated calcium channel activity. [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12754254] |
GO:1902261 | positive regulation of delayed rectifier potassium channel activity | biological_process | Any process that activates or increases the frequency, rate or extent of delayed rectifier potassium channel activity. [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11299204] |
GO:1902514 | regulation of calcium ion transmembrane transport via high voltage-gated calcium channel | biological_process | Any process that modulates the frequency, rate or extent of generation of calcium ion transmembrane transport via high voltage-gated calcium channel. [GOC:dph, GOC:pg, GOC:TermGenie, PMID:1611048] |
GO:1903762 | positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization | biological_process | Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization. [GO_REF:0000059, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18337493] |
GO:2000170 | positive regulation of peptidyl-cysteine S-nitrosylation | biological_process | Any process that activates or increases the frequency, rate or extent of peptidyl-cysteine S-nitrosylation. [GOC:obol] |
GO:0098978 | glutamatergic synapse | cellular_component | A synapse that uses glutamate as a neurotransmitter. [GOC:dos] |
GO:0002102 | podosome | cellular_component | An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm. [PMID:12837608, PMID:15890982] |
GO:0005634 | nucleus | cellular_component | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators] |
GO:0005739 | mitochondrion | cellular_component | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. [GOC:giardia, ISBN:0198506732] |
GO:0005829 | cytosol | cellular_component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |
GO:0030018 | Z disc | cellular_component | Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached. [GOC:mtg_muscle, ISBN:0815316194] |
GO:0030175 | filopodium | cellular_component | Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft. [GOC:mah, GOC:pr, ISBN:0815316194] |
GO:0033017 | sarcoplasmic reticulum membrane | cellular_component | The lipid bilayer surrounding the sarcoplasmic reticulum. [GOC:rph] |
GO:0042383 | sarcolemma | cellular_component | The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers. [ISBN:0198506732] |
GO:0048471 | perinuclear region of cytoplasm | cellular_component | Cytoplasm situated near, or occurring around, the nucleus. [GOC:jid] |
GO:0070161 | anchoring junction | cellular_component | A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix. [ISBN:0815332181] |
GO:0050998 | nitric-oxide synthase binding | molecular_function | Binding to nitric-oxide synthase. [GOC:ai] |