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NTMT2-202 ,NTMT2 ,Q5VVY1
  • Uniprot Accession= Q5VVY1
  • Ensembl Transcript= ENST00000439373.3
  • Uniprot Name= NTMT2
  • Name= N-terminal Xaa-Pro-Lys N-methyltransferase 2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 4
GO term GO name GO namespace GO def
GO:0071885 N-terminal protein N-methyltransferase activity molecular_function Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser. [PMID:20481588]
GO:0006480 N-terminal protein amino acid methylation biological_process The methylation of the N-terminal amino acid of a protein. [GOC:ai]
GO:0005634 nucleus cellular_component A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]