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OPN3-201 ,OPN3 ,Q9H1Y3
  • Uniprot Accession= Q9H1Y3
  • Ensembl Transcript= ENST00000366554.3
  • Uniprot Name= OPN3
  • Name= Opsin-3
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 24
GO term GO name GO namespace GO def
GO:0004930 G protein-coupled receptor activity molecular_function Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. [GOC:bf, http://www.iuphar-db.org, Wikipedia:GPCR]
GO:0005502 11-cis retinal binding molecular_function Binding to 11-cis retinal, an isomer of retinal that plays an important role in the visual process in most vertebrates. 11-cis retinal combines with opsin in the rods (scotopsin) to form rhodopsin or visual purple. Retinal is one of the three compounds that makes up vitamin A. [PMID:24403072]
GO:0005503 all-trans retinal binding molecular_function Binding to all-trans retinal, a compound that plays an important role in the visual process in most vertebrates. All-trans retinal (trans r., visual yellow) results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal is one of the forms of vitamin A. [GOC:curators]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0008020 G protein-coupled photoreceptor activity molecular_function Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. [GOC:bf, GOC:dph, ISBN:0198506732]
GO:0009881 photoreceptor activity molecular_function The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation. [GOC:ai, GOC:go_curators]
GO:0007602 phototransduction biological_process The sequence of reactions within a cell required to convert absorbed photons into a molecular signal. [GOC:go_curators]
GO:0009583 detection of light stimulus biological_process The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal. [GOC:go_curators]
GO:0009584 detection of visible light biological_process The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm. [GOC:go_curators, ISBN:0198506732]
GO:0009637 response to blue light biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. [GOC:ai, GOC:mtg_far_red]
GO:0030216 keratinocyte differentiation biological_process The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte. [GOC:dph, GOC:mah, GOC:sdb_2009, GOC:tb]
GO:0042752 regulation of circadian rhythm biological_process Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours. [GOC:dph, GOC:jl, GOC:tb]
GO:0043066 negative regulation of apoptotic process biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis]
GO:0046326 positive regulation of glucose import biological_process Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle. [GOC:ai, GOC:dph, GOC:tb]
GO:0048022 negative regulation of melanin biosynthetic process biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin. [GOC:jid]
GO:0048023 positive regulation of melanin biosynthetic process biological_process Any process that activates or increases the rate or extent of the chemical reactions and pathways resulting in the formation of melanin. [GOC:jid]
GO:0071492 cellular response to UV-A biological_process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm. [GOC:mah]
GO:1901857 positive regulation of cellular respiration biological_process Any process that activates or increases the frequency, rate or extent of cellular respiration. [GOC:TermGenie, GOC:yaf, PMID:23150719]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0016020 membrane cellular_component A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194]
GO:0001750 photoreceptor outer segment cellular_component The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins. [GOC:cilia, GOC:krc, GOC:pde, ISBN:0824072820, PMID:19501669, PMID:26574505, PMID:6771304]
GO:0007186 G protein-coupled receptor signaling pathway biological_process The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. [GOC:bf, GOC:mah, PMID:16902576, PMID:24568158, Wikipedia:G_protein-coupled_receptor]
GO:0071482 cellular response to light stimulus biological_process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light. [GOC:mah]