| GO term | GO name | GO namespace | GO def |
| GO:0006974 | DNA damage response | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. [GOC:go_curators] |
| GO:0007005 | mitochondrion organization | biological_process | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components. [GOC:dph, GOC:jl, GOC:mah, GOC:sgd_curators, PMID:9786946] |
| GO:0032042 | mitochondrial DNA metabolic process | biological_process | The chemical reactions and pathways involving mitochondrial DNA. [GOC:mah] |
| GO:0032880 | regulation of protein localization | biological_process | Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location. [GOC:dph, GOC:mah, GOC:tb] |
| GO:0034599 | cellular response to oxidative stress | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. [GOC:mah] |
| GO:0036211 | protein modification process | biological_process | The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). [GOC:bf, GOC:jl] |
| GO:0043504 | mitochondrial DNA repair | biological_process | The process of restoring mitochondrial DNA after damage. [PMID:12565799, PMID:15189144, PMID:16050976] |
| GO:0003677 | DNA binding | molecular_function | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). [GOC:dph, GOC:jl, GOC:tb, GOC:vw] |
| GO:0003682 | chromatin binding | molecular_function | Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. [GOC:jl, ISBN:0198506732, PMID:20404130] |
| GO:0003684 | damaged DNA binding | molecular_function | Binding to damaged DNA. [GOC:jl] |
| GO:0003723 | RNA binding | molecular_function | Binding to an RNA molecule or a portion thereof. [GOC:jl, GOC:mah] |
| GO:0003950 | NAD+ ADP-ribosyltransferase activity | molecular_function | Catalysis of the reaction |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0008270 | zinc ion binding | molecular_function | Binding to a zinc ion (Zn). [GOC:ai] |
| GO:0016779 | nucleotidyltransferase activity | molecular_function | Catalysis of the transfer of a nucleotidyl group to a reactant. [ISBN:0198506732] |
| GO:0019899 | enzyme binding | molecular_function | Binding to an enzyme, a protein with catalytic activity. [GOC:jl] |
| GO:0019901 | protein kinase binding | molecular_function | Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate. [GOC:jl] |
| GO:0030331 | nuclear estrogen receptor binding | molecular_function | Binding to a nuclear estrogen receptor. [GOC:ai] |
| GO:0031491 | nucleosome binding | molecular_function | Binding to a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures. [GOC:mah] |
| GO:0031625 | ubiquitin protein ligase binding | molecular_function | Binding to a ubiquitin protein ligase enzyme, any of the E3 proteins. [GOC:vp] |
| GO:0042802 | identical protein binding | molecular_function | Binding to an identical protein or proteins. [GOC:jl] |
| GO:0042803 | protein homodimerization activity | molecular_function | Binding to an identical protein to form a homodimer. [GOC:jl] |
| GO:0042826 | histone deacetylase binding | molecular_function | Binding to histone deacetylase. [GOC:jl] |
| GO:0051287 | NAD binding | molecular_function | Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH. [GOC:ai] |
| GO:0061629 | RNA polymerase II-specific DNA-binding transcription factor binding | molecular_function | Binding to a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription. [GOC:dph, GOC:vw] |
| GO:0070412 | R-SMAD binding | molecular_function | Binding to a receptor-regulated SMAD signaling protein. [GOC:BHF, GOC:vk, PMID:19114992] |
| GO:0140294 | NAD DNA ADP-ribosyltransferase activity | molecular_function | Catalysis of the transfer of the ADP-ribose group of NAD+ to a residue in double-stranded DNA. [PMID:27471034, PMID:29361132, PMID:29520010] |
| GO:0140537 | transcription regulator activator activity | molecular_function | A molecular function regulator that increases the activity of a transcription regulator via direct binding and/or post-translational modification. [PMID:9597751] |
| GO:0140805 | NAD+-protein-serine ADP-ribosyltransferase activity | molecular_function | Catalysis of the reaction |
| GO:0140806 | NAD+- protein-aspartate ADP-ribosyltransferase activity | molecular_function | Catalysis of the reaction |
| GO:0140807 | NAD+-protein-glutamate ADP-ribosyltransferase activity | molecular_function | Catalysis of the reaction |
| GO:0140808 | NAD+-protein-tyrosine ADP-ribosyltransferase activity | molecular_function | Catalysis of the reaction |
| GO:0140815 | NAD+-protein-histidine ADP-ribosyltransferase activity | molecular_function | Catalysis of the reaction |
| GO:0140816 | NAD+-histone H2BS6 serine ADP-ribosyltransferase activity | molecular_function | Catalysis of the transfer of ADP-ribose groups to the serine-6 or an equivalent residue of the N-terminal tail of histone H2B. [PMID:34874266] |
| GO:0140817 | NAD+-histone H3S10 serine ADP-ribosyltransferase activity | molecular_function | Catalysis of the transfer of ADP-ribose groups to the serine-10 or an equivalent residue of the N-terminal tail of histone H3. [PMID:34874266] |
| GO:0140822 | NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity | molecular_function | Catalysis of the transfer of ADP-ribose groups to the glutamate-35 residue of the N-terminal tail of histone H2B (or an equivalent residue). [PMID:32822587] |
| GO:1990404 | NAD+-protein ADP-ribosyltransferase activity | molecular_function | Catalysis of the reaction |
| GO:0000122 | negative regulation of transcription by RNA polymerase II | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. [GOC:go_curators, GOC:txnOH] |
| GO:0000723 | telomere maintenance | biological_process | Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences. [GOC:BHF, GOC:BHF_telomere, GOC:elh, GOC:rl, PMID:11092831] |
| GO:0006281 | DNA repair | biological_process | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. [PMID:11563486] |
| GO:0006302 | double-strand break repair | biological_process | The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix. [GOC:elh] |
| GO:0006366 | transcription by RNA polymerase II | biological_process | The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). [GOC:jl, GOC:txnOH, ISBN:0321000382] |
| GO:0006915 | apoptotic process | biological_process | A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. [GOC:cjm, GOC:dhl, GOC:ecd, GOC:go_curators, GOC:mtg_apoptosis, GOC:tb, ISBN:0198506732, PMID:18846107, PMID:21494263] |
| GO:0007179 | transforming growth factor beta receptor signaling pathway | biological_process | The series of molecular signals initiated by an extracellular ligand binding to a transforming growth factor beta receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:BHF, GOC:mah, GOC:signaling] |
| GO:0010332 | response to gamma radiation | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum. [GOC:tair_curators] |
| GO:0010613 | positive regulation of cardiac muscle hypertrophy | biological_process | Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. [GOC:BHF, GOC:dph, GOC:tb] |
| GO:0016051 | carbohydrate biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. [ISBN:0198506732] |
| GO:0016540 | protein autoprocessing | biological_process | Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein. [GOC:ai, PMID:9335337] |
| GO:0023019 | signal transduction involved in regulation of gene expression | biological_process | Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another. [GOC:mtg_signal] |
| GO:0030225 | macrophage differentiation | biological_process | The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage. [GOC:add, ISBN:0781735149] |
| GO:0030592 | DNA ADP-ribosylation | biological_process | The covalent attachment of an ADP-ribosyl group to a residue in double-stranded DNA. [PMID:11592983, PMID:27471034, PMID:29361132, PMID:29520010] |
| GO:0032786 | positive regulation of DNA-templated transcription, elongation | biological_process | Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase. [GOC:mah, GOC:txnOH] |
| GO:0032869 | cellular response to insulin stimulus | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. [GOC:mah, ISBN:0198506732] |
| GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway | biological_process | Any process that activates or increases the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway. [GOC:mah] |
| GO:0034244 | negative regulation of transcription elongation by RNA polymerase II | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II. [GOC:mah, GOC:txnOH] |
| GO:0034644 | cellular response to UV | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers. [GOC:mah] |
| GO:0043123 | positive regulation of canonical NF-kappaB signal transduction | biological_process | Any process that activates or increases the frequency, rate or extent of a canonical NF-kappaB signaling cascade. [GOC:jl] |
| GO:0044030 | regulation of DNA methylation | biological_process | Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine. [GOC:jl] |
| GO:0045087 | innate immune response | biological_process | Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. [GO_REF:0000022, GOC:add, GOC:ebc, GOC:mtg_sensu] |
| GO:0045188 | regulation of circadian sleep/wake cycle, non-REM sleep | biological_process | Any process that modulates the frequency, rate or extent of non-rapid eye movement sleep. [GOC:go_curators] |
| GO:0045824 | negative regulation of innate immune response | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response. [GOC:go_curators] |
| GO:0045892 | negative regulation of DNA-templated transcription | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. [GOC:go_curators, GOC:txnOH] |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | biological_process | Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. [GOC:go_curators, GOC:txnOH] |
| GO:0046697 | decidualization | biological_process | The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta. [ISBN:0721662544, PMID:11133685] |
| GO:0050790 | regulation of catalytic activity | biological_process | Any process that modulates the activity of an enzyme. [GOC:ai, GOC:ebc, GOC:vw] |
| GO:0051901 | positive regulation of mitochondrial depolarization | biological_process | Any process that activates, maintains or increases the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive. [GOC:ai] |
| GO:0060391 | positive regulation of SMAD protein signal transduction | biological_process | Any process that increases the rate, frequency or extent of SMAD protein signal transduction. [GOC:BHF, GOC:dph, GOC:tb] |
| GO:0060545 | positive regulation of necroptotic process | biological_process | Any process that increases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors. [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:tb] |
| GO:0070212 | protein poly-ADP-ribosylation | biological_process | The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain. [GOC:BHF, GOC:mah, GOC:rl, PMID:25043379] |
| GO:0070213 | protein auto-ADP-ribosylation | biological_process | The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein. [GOC:BHF, GOC:rl] |
| GO:0071168 | protein localization to chromatin | biological_process | Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin. [GOC:mah] |
| GO:0071294 | cellular response to zinc ion | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus. [GOC:mah] |
| GO:0071932 | replication fork reversal | biological_process | Replication fork processing that involves the unwinding of blocked forks to form four-stranded structures resembling Holliday junctions, which are subsequently resolved. [PMID:19406929] |
| GO:0160049 | negative regulation of cGAS/STING signaling pathway | biological_process | Any process that stops, prevents or reduces the frequency, rate or extent of cGAS/STING signaling pathway. [PMID:29875158] |
| GO:1900182 | positive regulation of protein localization to nucleus | biological_process | Any process that activates or increases the frequency, rate or extent of protein localization to nucleus. [GOC:TermGenie] |
| GO:1903376 | regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway | biological_process | Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway. [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie] |
| GO:1903518 | positive regulation of single strand break repair | biological_process | Any process that activates or increases the frequency, rate or extent of single strand break repair. [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17395247] |
| GO:1904044 | response to aldosterone | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus. [GO_REF:0000071, GOC:TermGenie, PMID:17644563] |
| GO:1904178 | negative regulation of adipose tissue development | biological_process | Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development. [GO_REF:0000058, GOC:TermGenie, PMID:23081848] |
| GO:1904357 | negative regulation of telomere maintenance via telomere lengthening | biological_process | Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance via telomere lengthening. [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23959892] |
| GO:1904646 | cellular response to amyloid-beta | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus. [GO_REF:0000071, GOC:TermGenie, PMID:23555824] |
| GO:1904762 | positive regulation of myofibroblast differentiation | biological_process | Any process that activates or increases the frequency, rate or extent of myofibroblast differentiation. [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20533548] |
| GO:1905051 | regulation of base-excision repair | biological_process | Any process that modulates the frequency, rate or extent of base-excision repair. [GO_REF:0000058, GOC:ah, GOC:TermGenie, PMID:18973764] |
| GO:1905168 | positive regulation of double-strand break repair via homologous recombination | biological_process | Any process that activates or increases the frequency, rate or extent of double-strand break repair via homologous recombination. [GO_REF:0000058, GOC:TermGenie, PMID:12023299] |
| GO:1990090 | cellular response to nerve growth factor stimulus | biological_process | A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus. [PMID:22399805, Wikipedia:Nerve_growth_factor] |
| GO:1990966 | ATP generation from poly-ADP-D-ribose | biological_process | The process of generating ATP in the nucleus from poly-ADP-D-ribose. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming. [PMID:27257257] |
| GO:2001170 | negative regulation of ATP biosynthetic process | biological_process | Any process that stops, prevents or reduces the frequency, rate or extent of ATP biosynthetic process. [GOC:obol] |
| GO:0005634 | nucleus | cellular_component | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators] |
| GO:0005829 | cytosol | cellular_component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |
| GO:0035861 | site of double-strand break | cellular_component | A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix. [GOC:bf, GOC:mah, GOC:vw, PMID:20096808, PMID:21035408] |
| GO:0043596 | nuclear replication fork | cellular_component | The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes. [GOC:jl, GOC:mtg_sensu] |
| GO:0090734 | site of DNA damage | cellular_component | A region of a chromosome at which DNA damage has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix. [GOC:pg] |
| GO:0000781 | chromosome, telomeric region | cellular_component | The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. D. melanogaster telomeres). [GOC:elh] |
| GO:0005635 | nuclear envelope | cellular_component | The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space). [ISBN:0198547684] |
| GO:0005654 | nucleoplasm | cellular_component | That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653] |
| GO:0005730 | nucleolus | cellular_component | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. [ISBN:0198506732] |
| GO:0005739 | mitochondrion | cellular_component | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. [GOC:giardia, ISBN:0198506732] |
| GO:0016020 | membrane | cellular_component | A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194] |
| GO:0016604 | nuclear body | cellular_component | Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins. [GOC:ma, PMID:10330182] |
| GO:0000785 | chromatin | cellular_component | The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. [GOC:elh, PMID:20404130] |
| GO:0005667 | transcription regulator complex | cellular_component | A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription. [GOC:jl] |
| GO:0032991 | protein-containing complex | cellular_component | A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. [GOC:dos, GOC:mah] |
| GO:0032993 | protein-DNA complex | cellular_component | A macromolecular complex containing both protein and DNA molecules. [GOC:mah] |