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PDZK1-202 ,PDZK1 ,Q5T2W1
  • Uniprot Accession= Q5T2W1
  • Ensembl Transcript= ENST00000417171.6
  • Uniprot Name= PDZK1
  • Name= Na(+)/H(+) exchange regulatory cofactor NHE-RF3
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 20
GO term GO name GO namespace GO def
GO:0005124 scavenger receptor binding molecular_function Binding to scavenger receptors, a family of proteins that are expressed on myeloid cells and are involved in the uptake of effete cellular components and foreign particles. [GOC:ceb]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0030165 PDZ domain binding molecular_function Binding to a PDZ domain of a protein, a domain found in diverse signaling proteins. [GOC:go_curators, Pfam:PF00595]
GO:0044877 protein-containing complex binding molecular_function Binding to a macromolecular complex. [GOC:jl]
GO:0015879 carnitine transport biological_process The directed movement of carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane. [GOC:ai]
GO:0032414 positive regulation of ion transmembrane transporter activity biological_process Any process that activates or increases the activity of an ion transporter. [GOC:mah, GOC:tb]
GO:0044070 regulation of monoatomic anion transport biological_process Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:jl]
GO:0090314 positive regulation of protein targeting to membrane biological_process Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein. [GOC:tb]
GO:1904064 positive regulation of cation transmembrane transport biological_process Any process that activates or increases the frequency, rate or extent of cation transmembrane transport. [GO_REF:0000058, GOC:TermGenie, PMID:15304482]
GO:1905477 positive regulation of protein localization to membrane biological_process Any process that activates or increases the frequency, rate or extent of protein localization to membrane. [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690]
GO:1990961 xenobiotic detoxification by transmembrane export across the plasma membrane biological_process A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell. [PMID:28355133]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0005903 brush border cellular_component The dense covering of microvilli on the apical surface of an epithelial cell in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell. [GOC:sl, ISBN:0815316194]
GO:0031526 brush border membrane cellular_component The portion of the plasma membrane surrounding the brush border. [GOC:mah]
GO:0031528 microvillus membrane cellular_component The portion of the plasma membrane surrounding a microvillus. [GOC:mah]
GO:0070062 extracellular exosome cellular_component A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894]
GO:0005102 signaling receptor binding molecular_function Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. [GOC:bf, GOC:ceb, ISBN:0198506732]
GO:0016324 apical plasma membrane cellular_component The region of the plasma membrane located at the apical end of the cell. [GOC:curators]
GO:0043495 protein-membrane adaptor activity molecular_function The binding activity of a molecule that brings together a protein or a protein complex with a membrane, or bringing together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex or organelle. [GOC:go_curators]
GO:0072659 protein localization to plasma membrane biological_process A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane. [GOC:mah]