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PGLYRP4-201 ,PGLYRP4 ,Q96LB8
  • Uniprot Accession= Q96LB8
  • Ensembl Transcript= ENST00000359650.10
  • Uniprot Name= PGLYRP4
  • Name= Peptidoglycan recognition protein 4
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 14
GO term GO name GO namespace GO def
GO:0008270 zinc ion binding molecular_function Binding to a zinc ion (Zn). [GOC:ai]
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular_function Catalysis of the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain bacterial cell-wall glycopeptides. [EC:3.5.1.28, PMID:22748813]
GO:0016019 peptidoglycan immune receptor activity molecular_function Combining with a peptidoglycan and transmitting the signal to initiate an innate immune response. [PMID:14698226]
GO:0042834 peptidoglycan binding molecular_function Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls. [GOC:go_curators, PMID:14698226]
GO:0046982 protein heterodimerization activity molecular_function Binding to a nonidentical protein to form a heterodimer. [GOC:ai]
GO:0009253 peptidoglycan catabolic process biological_process The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls. [http://www.dsmz.de/species/murein.htm, ISBN:0198506732]
GO:0016045 detection of bacterium biological_process The series of events in which a stimulus from a bacterium is received and converted into a molecular signal. [GOC:hb]
GO:0031640 killing of cells of another organism biological_process Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions. [GOC:add]
GO:0045087 innate immune response biological_process Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. [GO_REF:0000022, GOC:add, GOC:ebc, GOC:mtg_sensu]
GO:0050830 defense response to Gram-positive bacterium biological_process Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism. [GOC:ai]
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide biological_process An immune response against microbes mediated by anti-microbial peptides in body fluid. [PMID:15761415, PMID:24287494]
GO:0005576 extracellular region cellular_component The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. [GOC:go_curators]
GO:0016020 membrane cellular_component A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194]
GO:0032991 protein-containing complex cellular_component A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. [GOC:dos, GOC:mah]