| GO term | GO name | GO namespace | GO def |
| GO:0001784 | phosphotyrosine residue binding | molecular_function | Binding to a phosphorylated tyrosine residue within a protein. [PMID:14636584] |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0016303 | 1-phosphatidylinositol-3-kinase activity | molecular_function | Catalysis of the reaction |
| GO:0001934 | positive regulation of protein phosphorylation | biological_process | Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein. [GOC:hjd] |
| GO:0002042 | cell migration involved in sprouting angiogenesis | biological_process | The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels involved in sprouting angiogenesis. [PMID:16391003] |
| GO:0006955 | immune response | biological_process | Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. [GO_REF:0000022, GOC:add] |
| GO:0010628 | positive regulation of gene expression | biological_process | Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). [GOC:txnOH-2018] |
| GO:0030183 | B cell differentiation | biological_process | The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity. [GO_REF:0000022, GOC:mah] |
| GO:0030217 | T cell differentiation | biological_process | The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex. [GO_REF:0000022, GOC:jid, GOC:mah] |
| GO:0030335 | positive regulation of cell migration | biological_process | Any process that activates or increases the frequency, rate or extent of cell migration. [GOC:go_curators] |
| GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of phosphatidylinositol-3-phosphate, a phosphatidylinositol monophosphate carrying the phosphate group at the 3-position. [GOC:al, GOC:vw] |
| GO:0043491 | phosphatidylinositol 3-kinase/protein kinase B signal transduction | biological_process | An intracellular signaling cassette that starts with phosphatidylinositol 3-kinase (PI3K) activation, production of phosphatidylinositol 3-phosphate (PI3P), activation of PDK1, which recruits and ending with the activation of protein kinase B (PKB, also known as Akt). PI3K is activated by cell surface receptors. Note that PTEN is an inhibitor of the pathway. [PMID:20517722, PMID:22952397] |
| GO:2000811 | negative regulation of anoikis | biological_process | Any process that stops, prevents or reduces the frequency, rate or extent of anoikis. [GOC:obol] |
| GO:0005829 | cytosol | cellular_component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |
| GO:0005943 | phosphatidylinositol 3-kinase complex, class IA | cellular_component | A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IA phosphoinositide 3-kinase (PI3K) subunit and an associated SH2 domain-containing regulatory subunit that is a member of a family of related proteins often called p85 proteins. Through the interaction with the SH2-containing adaptor subunits, Class IA PI3K catalytic subunits are linked to tyrosine kinase signaling pathways. [PMID:9255069, PMID:9759495] |
| GO:0046854 | phosphatidylinositol phosphate biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of phosphatidylinositol phosphate. [ISBN:0198506732] |
| GO:0005942 | phosphatidylinositol 3-kinase complex | cellular_component | A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too. [GOC:bf, PMID:24587488] |
| GO:0008286 | insulin receptor signaling pathway | biological_process | The series of molecular signals generated as a consequence of the insulin receptor binding to insulin. [GOC:ceb] |
| GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity | molecular_function | Modulates the activity of the enzyme 1-phosphatidylinositol-3-kinase activity. [GOC:ai] |