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PLA2G2D-201 ,PLA2G2D ,Q9UNK4
  • Uniprot Accession= Q9UNK4
  • Ensembl Transcript= ENST00000375105.8
  • Uniprot Name= PLA2G2D
  • Name= Group IID secretory phospholipase A2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 17
GO term GO name GO namespace GO def
GO:0004623 phospholipase A2 activity molecular_function Catalysis of the reaction
GO:0008201 heparin binding molecular_function Binding to heparin, a member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. [GOC:jl, ISBN:0198506732]
GO:0043395 heparan sulfate proteoglycan binding molecular_function Binding to a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit. [ISBN:0198506732]
GO:0047498 calcium-dependent phospholipase A2 activity molecular_function Catalysis of the reaction
GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation biological_process The process in which a precursor cell type acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell. [GOC:add, PMID:15207821]
GO:0002864 regulation of acute inflammatory response to antigenic stimulus biological_process Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus. [GOC:add]
GO:0006954 inflammatory response biological_process The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. [GO_REF:0000022, ISBN:0198506732]
GO:0016042 lipid catabolic process biological_process The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. [GOC:go_curators]
GO:0046337 phosphatidylethanolamine metabolic process biological_process The chemical reactions and pathways involving phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. It is a major structural phospholipid in mammalian systems. It tends to be more abundant than phosphatidylcholine in the internal membranes of the cell and is an abundant component of prokaryotic membranes. [GOC:curators, ISBN:0198506732]
GO:0046470 phosphatidylcholine metabolic process biological_process The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes. [ISBN:0198506732]
GO:0046471 phosphatidylglycerol metabolic process biological_process The chemical reactions and pathways involving phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. They are important constituents of cell membranes. [ISBN:0198506732]
GO:0050482 arachidonic acid secretion biological_process The controlled release of arachidonic acid from a cell or a tissue. [GOC:ai]
GO:0005576 extracellular region cellular_component The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. [GOC:go_curators]
GO:0005543 phospholipid binding molecular_function Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester. [ISBN:0198506732]
GO:0005509 calcium ion binding molecular_function Binding to a calcium ion (Ca2+). [GOC:ai]
GO:0006644 phospholipid metabolic process biological_process The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester. [ISBN:0198506732]
GO:0042130 negative regulation of T cell proliferation biological_process Any process that stops, prevents or reduces the rate or extent of T cell proliferation. [GOC:jl]