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PLOD1-201 ,PLOD1 ,Q02809
  • Uniprot Accession= Q02809
  • Ensembl Transcript= ENST00000196061.5
  • Uniprot Name= PLOD1
  • Name= Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 14
GO term GO name GO namespace GO def
GO:0033823 procollagen glucosyltransferase activity molecular_function Catalysis of the reaction
GO:0006493 protein O-linked glycosylation biological_process A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the hydroxyl group of peptidyl-serine, peptidyl-threonine, peptidyl-hydroxylysine, or peptidyl-hydroxyproline, or via the phenol group of peptidyl-tyrosine, forming an O-glycan. [GOC:pr, ISBN:0879695595, RESID:AA0153, RESID:AA0154, RESID:AA0155, RESID:AA0157, RESID:AA0212]
GO:0005506 iron ion binding molecular_function Binding to an iron (Fe) ion. [GOC:ai]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0008475 procollagen-lysine 5-dioxygenase activity molecular_function Catalysis of the reaction
GO:0031418 L-ascorbic acid binding molecular_function Binding to L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species. [GOC:mah]
GO:0001666 response to hypoxia biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. [GOC:hjd]
GO:0008544 epidermis development biological_process The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. [GOC:go_curators, UBERON:0001003]
GO:0017185 peptidyl-lysine hydroxylation biological_process The hydroxylation of peptidyl-lysine to form peptidyl-hydroxylysine. [GOC:ai]
GO:0005789 endoplasmic reticulum membrane cellular_component The lipid bilayer surrounding the endoplasmic reticulum. [GOC:mah]
GO:0030867 rough endoplasmic reticulum membrane cellular_component The lipid bilayer surrounding the rough endoplasmic reticulum. [GOC:mah]
GO:0070062 extracellular exosome cellular_component A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894]
GO:1902494 catalytic complex cellular_component A protein complex which is capable of catalytic activity. [GOC:bhm, GOC:TermGenie, PMID:8077207]
GO:0005783 endoplasmic reticulum cellular_component The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). [ISBN:0198506732]