GO term | GO name | GO namespace | GO def |
GO:0007229 | integrin-mediated signaling pathway | biological_process | The series of molecular signals initiated by an extracellular ligand binding to an integrin on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mah, GOC:signaling] |
GO:0005178 | integrin binding | molecular_function | Binding to an integrin. [GOC:ceb] |
GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
GO:0008195 | phosphatidate phosphatase activity | molecular_function | Catalysis of the reaction |
GO:0042392 | sphingosine-1-phosphate phosphatase activity | molecular_function | Catalysis of the reaction |
GO:0106235 | ceramide-1-phosphate phosphatase activity | molecular_function | Catalysis of the reaction |
GO:0001568 | blood vessel development | biological_process | The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood. [GOC:hjd, UBERON:0001981] |
GO:0001702 | gastrulation with mouth forming second | biological_process | A gastrulation process in which the initial invagination becomes the anus and the mouth forms second. [GOC:go_curators, GOC:mtg_sensu] |
GO:0001933 | negative regulation of protein phosphorylation | biological_process | Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein. [GOC:hjd] |
GO:0006644 | phospholipid metabolic process | biological_process | The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester. [ISBN:0198506732] |
GO:0006665 | sphingolipid metabolic process | biological_process | The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). [GOC:mah, ISBN:0198506732] |
GO:0006670 | sphingosine metabolic process | biological_process | The chemical reactions and pathways involving sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues. [GOC:ma, ISBN:0198506732] |
GO:0006672 | ceramide metabolic process | biological_process | The chemical reactions and pathways involving ceramides, any N-acylated sphingoid. [ISBN:0198547684] |
GO:0006890 | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum | biological_process | The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG. [ISBN:0716731363, PMID:16510524] |
GO:0010595 | positive regulation of endothelial cell migration | biological_process | Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. [GOC:BHF, GOC:dph, GOC:tb] |
GO:0022409 | positive regulation of cell-cell adhesion | biological_process | Any process that activates or increases the rate or extent of cell adhesion to another cell. [GOC:isa_complete] |
GO:0030111 | regulation of Wnt signaling pathway | biological_process | Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway. [GOC:dph, GOC:mah, GOC:tb] |
GO:0033631 | cell-cell adhesion mediated by integrin | biological_process | The attachment of one cell to another cell via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits. [GOC:add, PMID:12213832, PMID:14754902] |
GO:0034109 | homotypic cell-cell adhesion | biological_process | The attachment of a cell to a second cell of the identical type via adhesion molecules. [GOC:add] |
GO:0042060 | wound healing | biological_process | The series of events that restore integrity to a damaged tissue, following an injury. [GOC:bf, PMID:15269788] |
GO:0046839 | phospholipid dephosphorylation | biological_process | The process of removing one or more phosphate groups from a phosphorylated lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents. [ISBN:0198506732] |
GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | biological_process | Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine. [GOC:ai] |
GO:0050821 | protein stabilization | biological_process | Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation. [GOC:ai] |
GO:0051091 | positive regulation of DNA-binding transcription factor activity | biological_process | Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription. [GOC:ai] |
GO:0060020 | Bergmann glial cell differentiation | biological_process | The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate. [GOC:dph, PMID:10375501] |
GO:1902068 | regulation of sphingolipid mediated signaling pathway | biological_process | Any process that modulates the frequency, rate or extent of sphingolipid signaling. [GOC:TermGenie, PMID:20870412] |
GO:0000139 | Golgi membrane | cellular_component | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. [GOC:mah] |
GO:0005789 | endoplasmic reticulum membrane | cellular_component | The lipid bilayer surrounding the endoplasmic reticulum. [GOC:mah] |
GO:0005794 | Golgi apparatus | cellular_component | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. [ISBN:0198506732] |
GO:0005802 | trans-Golgi network | cellular_component | The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination. [GOC:vw, ISBN:0815316194] |
GO:0005886 | plasma membrane | cellular_component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
GO:0005912 | adherens junction | cellular_component | A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules. [GOC:aruk, GOC:bc, GOC:mah, ISBN:0198506732, PMID:17854762, PMID:20571587, PMID:21422226, PMID:28096264] |
GO:0016020 | membrane | cellular_component | A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194] |
GO:0016323 | basolateral plasma membrane | cellular_component | The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis. [GOC:go_curators] |
GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane | cellular_component | The lipid bilayer surrounding any of the compartments of the endoplasmic reticulum (ER)-Golgi intermediate compartment system. [GOC:mah, GOC:pr, PMID:16723730] |
GO:0045121 | membrane raft | cellular_component | Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions. [PMID:16645198, PMID:20044567] |
GO:0070971 | endoplasmic reticulum exit site | cellular_component | An endoplasmic reticulum part at which COPII-coated vesicles are produced. [NIF_Subcellular:sao124393998, PMID:15623529, PMID:16957052] |
GO:0007165 | signal transduction | biological_process | The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. [GOC:go_curators, GOC:mtg_signaling_feb11] |
GO:0098609 | cell-cell adhesion | biological_process | The attachment of one cell to another cell via adhesion molecules. [GOC:dos] |