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PLXNA2-201 ,PLXNA2 ,O75051
  • Uniprot Accession= O75051
  • Ensembl Transcript= ENST00000367033.4
  • Uniprot Name= PLXNA2
  • Name= Plexin-A2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 17
GO term GO name GO namespace GO def
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0017154 semaphorin receptor activity molecular_function Combining with a semaphorin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. [GOC:mah, GOC:signaling, PMID:15239958]
GO:0042802 identical protein binding molecular_function Binding to an identical protein or proteins. [GOC:jl]
GO:0001756 somitogenesis biological_process The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. [ISBN:0721662544]
GO:0021915 neural tube development biological_process The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]
GO:0021935 cerebellar granule cell precursor tangential migration biological_process The early migration of granule cell precursors in which cells move orthogonal to the direction of radial migration and ultimately cover the superficial zone of the cerebellar primordium. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725]
GO:0030334 regulation of cell migration biological_process Any process that modulates the frequency, rate or extent of cell migration. [GOC:go_curators]
GO:0051642 centrosome localization biological_process Any process in which a centrosome is transported to, and/or maintained in, a specific location within the cell. [GOC:ai]
GO:0060037 pharyngeal system development biological_process The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming
GO:0060174 limb bud formation biological_process The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable. [GOC:dgh, GOC:dph]
GO:0071526 semaphorin-plexin signaling pathway biological_process The series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand. [GOC:BHF, GOC:mah, GOC:vk, PMID:15239959]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0002116 semaphorin receptor complex cellular_component A stable binary complex of a semaphorin and a plexin, together forming a functional semaphorin receptor. [GOC:hjd, PMID:10934324, PMID:12367632, PMID:12613544]
GO:0008360 regulation of cell shape biological_process Any process that modulates the surface configuration of a cell. [GOC:dph, GOC:go_curators, GOC:tb]
GO:0043087 regulation of GTPase activity biological_process Any process that modulates the rate of GTP hydrolysis by a GTPase. [GOC:jl, GOC:mah]
GO:0007162 negative regulation of cell adhesion biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion. [GOC:go_curators]
GO:0050772 positive regulation of axonogenesis biological_process Any process that activates or increases the frequency, rate or extent of axonogenesis. [GOC:ai]