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PPP1R15B-201 ,PPP1R15B ,Q5SWA1
  • Uniprot Accession= Q5SWA1
  • Ensembl Transcript= ENST00000367188.5
  • Uniprot Name= PPP1R15B
  • Name= Protein phosphatase 1 regulatory subunit 15B
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 12
GO term GO name GO namespace GO def
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0001933 negative regulation of protein phosphorylation biological_process Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein. [GOC:hjd]
GO:0006417 regulation of translation biological_process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. [GOC:isa_complete]
GO:0006983 ER overload response biological_process The series of molecular signals initiated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum and leading to activation of transcription by NF-kappaB. [PMID:10390516]
GO:0042542 response to hydrogen peroxide biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus. [GOC:jl]
GO:1902310 positive regulation of peptidyl-serine dephosphorylation biological_process Any process that activates or increases the frequency, rate or extent of peptidyl-serine dephosphorylation. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:11953308]
GO:1903898 negative regulation of PERK-mediated unfolded protein response biological_process Any process that stops, prevents or reduces the frequency, rate or extent of the PERK-mediated unfolded protein response. [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22013210]
GO:0000164 protein phosphatase type 1 complex cellular_component A protein complex that possesses magnesium-dependent protein serine/threonine phosphatase (AMD phosphatase) activity, and consists of a catalytic subunit and one or more regulatory subunits that dictates the phosphatase's substrate specificity, function, and activity. [GOC:mah, GOC:ssd]
GO:0032516 positive regulation of phosphoprotein phosphatase activity biological_process Any process that activates or increases the activity of a phosphoprotein phosphatase. [GOC:mah]
GO:0005783 endoplasmic reticulum cellular_component The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). [ISBN:0198506732]
GO:0019888 protein phosphatase regulator activity molecular_function Binds to and modulates the activity of a protein phosphatase. [GOC:ai]
GO:0034976 response to endoplasmic reticulum stress biological_process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen. [GOC:cjm, GOC:mah]