GO term | GO name | GO namespace | GO def |
GO:0003723 | RNA binding | molecular_function | Binding to an RNA molecule or a portion thereof. [GOC:jl, GOC:mah] |
GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
GO:0000398 | mRNA splicing, via spliceosome | biological_process | The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. [GOC:krc, ISBN:0198506732, ISBN:0879695897] |
GO:0005634 | nucleus | cellular_component | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators] |
GO:0005654 | nucleoplasm | cellular_component | That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653] |
GO:0071005 | U2-type precatalytic spliceosome | cellular_component | A spliceosomal complex that is formed by the recruitment of the preassembled U4/U6.U5 tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U1, U2 and U4/U6.U5 snRNPs. [GOC:ab, GOC:krc, GOC:mah, PMID:18322460, PMID:19239890] |
GO:0071011 | precatalytic spliceosome | cellular_component | A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs. [GOC:ab, GOC:krc, GOC:mah, PMID:18322460, PMID:19239890] |