| GO term | GO name | GO namespace | GO def |
| GO:0005119 | smoothened binding | molecular_function | Binding to a smoothened (smo) protein, which interacts with patched to transmit hedgehog signals. [GOC:ceb, PMID:11731473] |
| GO:0008158 | hedgehog receptor activity | molecular_function | Combining with a member of the hedgehog protein family and transmitting the signal across the membrane to initiate a change in cell activity. [GOC:bf, GOC:go_curators, PMID:9278137] |
| GO:0097108 | hedgehog family protein binding | molecular_function | Binding to a member of the hedgehog protein family, signaling proteins involved in development. [GOC:BHF, GOC:pr, PMID:10050855] |
| GO:0001558 | regulation of cell growth | biological_process | Any process that modulates the frequency, rate, extent or direction of cell growth. [GOC:go_curators] |
| GO:0001709 | cell fate determination | biological_process | The cellular developmental process involved in cell fate commitment that occurs after cell fate specification, in which a cell is irreversibly committed to a cellular developmental fate which is heritable on cell division. [ISBN:0878932437] |
| GO:0009957 | epidermal cell fate specification | biological_process | The process in which a cell becomes capable of differentiating autonomously into an epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. [GOC:mtg_sensu, GOC:sm] |
| GO:0042633 | hair cycle | biological_process | The cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body. [GOC:go_curators, PMID:12230507] |
| GO:0043588 | skin development | biological_process | The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. [GOC:jl, UBERON:0002097] |
| GO:0045606 | positive regulation of epidermal cell differentiation | biological_process | Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation. [GOC:go_curators] |
| GO:0045879 | negative regulation of smoothened signaling pathway | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling. [GOC:go_curators] |
| GO:0005886 | plasma membrane | cellular_component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |