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PTPRF-201 ,PTPRF ,P10586
  • Uniprot Accession= P10586
  • Ensembl Transcript= ENST00000359947.9
  • Uniprot Name= PTPRF
  • Name= Receptor-type tyrosine-protein phosphatase F
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 18
GO term GO name GO namespace GO def
GO:0004725 protein tyrosine phosphatase activity molecular_function Catalysis of the reaction
GO:0005001 transmembrane receptor protein tyrosine phosphatase activity molecular_function Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction
GO:0008201 heparin binding molecular_function Binding to heparin, a member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. [GOC:jl, ISBN:0198506732]
GO:0035373 chondroitin sulfate proteoglycan binding molecular_function Binding to a chondroitin sulfate proteoglycan, any proteoglycan containing chondroitin sulfate as the glycosaminoglycan carbohydrate unit. [GOC:kmv, ISBN:0198506732]
GO:0044877 protein-containing complex binding molecular_function Binding to a macromolecular complex. [GOC:jl]
GO:0050839 cell adhesion molecule binding molecular_function Binding to a cell adhesion molecule. [GOC:ai]
GO:0007155 cell adhesion biological_process The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. [GOC:hb, GOC:pf]
GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway biological_process The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses protein tyrosine phosphatase activity, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mah, GOC:signaling]
GO:0016477 cell migration biological_process The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. [GOC:cjm, GOC:dph, GOC:ems, GOC:pf, Wikipedia:Cell_migration]
GO:0031102 neuron projection regeneration biological_process The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage. [GOC:dgh, GOC:dph, GOC:tb]
GO:0035335 peptidyl-tyrosine dephosphorylation biological_process The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine. [GOC:bf]
GO:0048679 regulation of axon regeneration biological_process Any process that modulates the frequency, rate or extent of axon regeneration. [GOC:dgh, GOC:dph, GOC:jid, GOC:lm]
GO:0099560 synaptic membrane adhesion biological_process The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane. [GOC:dos]
GO:1900121 negative regulation of receptor binding biological_process Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor. [GOC:signaling, GOC:TermGenie]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0043005 neuron projection cellular_component A prolongation or process extending from a nerve cell, e.g. an axon or dendrite. [GOC:jl, http://www.cogsci.princeton.edu/~wn/]
GO:0043025 neuronal cell body cellular_component The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites. [GOC:go_curators]
GO:0070062 extracellular exosome cellular_component A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894]