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PTPRU-201 ,PTPRU ,Q92729
  • Uniprot Accession= Q92729
  • Ensembl Transcript= ENST00000345512.7
  • Uniprot Name= PTPRU
  • Name= Receptor-type tyrosine-protein phosphatase U
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 18
GO term GO name GO namespace GO def
GO:0004725 protein tyrosine phosphatase activity molecular_function Catalysis of the reaction
GO:0005001 transmembrane receptor protein tyrosine phosphatase activity molecular_function Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0008013 beta-catenin binding molecular_function Binding to a catenin beta subunit. [GOC:bf]
GO:0006470 protein dephosphorylation biological_process The process of removing one or more phosphoric residues from a protein. [GOC:hb]
GO:0007155 cell adhesion biological_process The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. [GOC:hb, GOC:pf]
GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway biological_process The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses protein tyrosine phosphatase activity, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mah, GOC:signaling]
GO:0008285 negative regulation of cell population proliferation biological_process Any process that stops, prevents or reduces the rate or extent of cell proliferation. [GOC:go_curators]
GO:0030154 cell differentiation biological_process The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. [ISBN:0198506732]
GO:0030336 negative regulation of cell migration biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration. [GOC:go_curators]
GO:0031100 animal organ regeneration biological_process The regrowth of a lost or destroyed animal organ. [GOC:mah]
GO:0034109 homotypic cell-cell adhesion biological_process The attachment of a cell to a second cell of the identical type via adhesion molecules. [GOC:add]
GO:0034394 protein localization to cell surface biological_process A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane. [GOC:mah]
GO:0051384 response to glucocorticoid biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. [GOC:ai, PMID:9884123]
GO:0090090 negative regulation of canonical Wnt signaling pathway biological_process Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. [GOC:dph, GOC:tb]
GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin biological_process Any process that activates or increases the frequency, rate or extent of cell-cell adhesion mediated by cadherin. [GOC:obol]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0005911 cell-cell junction cellular_component A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects. [GOC:aruk, GOC:bc, GOC:dgh, GOC:hb, GOC:mah, PMID:21422226, PMID:28096264]