GO term | GO name | GO namespace | GO def |
GO:0005085 | guanyl-nucleotide exchange factor activity | molecular_function | Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions. [GOC:kd, GOC:mah, PMID:23303910, PMID:27218782] |
GO:0005096 | GTPase activator activity | molecular_function | Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP. [GOC:mah] |
GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
GO:0008047 | enzyme activator activity | molecular_function | Binds to and increases the activity of an enzyme. [GOC:dph, GOC:mah, GOC:tb] |
GO:0030234 | enzyme regulator activity | molecular_function | Binds to and modulates the activity of an enzyme. [GOC:dph, GOC:mah, GOC:tb] |
GO:0031267 | small GTPase binding | molecular_function | Binding to a small monomeric GTPase. [GOC:mah, PMID:27218782] |
GO:0006886 | intracellular protein transport | biological_process | The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. [GOC:mah] |
GO:0043087 | regulation of GTPase activity | biological_process | Any process that modulates the rate of GTP hydrolysis by a GTPase. [GOC:jl, GOC:mah] |
GO:0097051 | establishment of protein localization to endoplasmic reticulum membrane | biological_process | The directed movement of a protein to a specific location in the endoplasmic reticulum membrane. [GOC:rb, PMID:9388185] |
GO:1903061 | positive regulation of protein lipidation | biological_process | Any process that activates or increases the frequency, rate or extent of protein lipidation. [GO_REF:0000058, GOC:rph, GOC:TermGenie, PMID:21909394] |
GO:1903373 | positive regulation of endoplasmic reticulum tubular network organization | biological_process | Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum tubular network organization. [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:24891604] |
GO:2000786 | positive regulation of autophagosome assembly | biological_process | Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly. [GOC:autophagy, GOC:BHF] |
GO:0005789 | endoplasmic reticulum membrane | cellular_component | The lipid bilayer surrounding the endoplasmic reticulum. [GOC:mah] |
GO:0005829 | cytosol | cellular_component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |
GO:0005886 | plasma membrane | cellular_component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
GO:0032991 | protein-containing complex | cellular_component | A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. [GOC:dos, GOC:mah] |