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RALGPS2-204 ,RALGPS2 ,Q86X27
  • Uniprot Accession= Q86X27
  • Ensembl Transcript= ENST00000367635.8
  • Uniprot Name= RALGPS2
  • Name= Ras-specific guanine nucleotide-releasing factor RalGPS2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 6
GO term GO name GO namespace GO def
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0043547 positive regulation of GTPase activity biological_process Any process that activates or increases the activity of a GTPase. [GOC:jl, GOC:mah]
GO:0005085 guanyl-nucleotide exchange factor activity molecular_function Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions. [GOC:kd, GOC:mah, PMID:23303910, PMID:27218782]
GO:0007265 Ras protein signal transduction biological_process An intracellular signaling cassette in which a small monomeric GTPase of the Ras subfamily relays a signal. [GOC:bf]