| GO term | GO name | GO namespace | GO def |
| GO:0003723 | RNA binding | molecular_function | Binding to an RNA molecule or a portion thereof. [GOC:jl, GOC:mah] |
| GO:0003725 | double-stranded RNA binding | molecular_function | Binding to double-stranded RNA. [GOC:jl] |
| GO:0003730 | mRNA 3'-UTR binding | molecular_function | Binding to a 3' untranslated region of an mRNA molecule. [GOC:mah] |
| GO:0004842 | ubiquitin-protein transferase activity | molecular_function | Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y = Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages. [GOC:BioGRID, GOC:jh2, PMID:9635407] |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0008270 | zinc ion binding | molecular_function | Binding to a zinc ion (Zn). [GOC:ai] |
| GO:0035198 | miRNA binding | molecular_function | Binding to a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes. [PMID:15066283] |
| GO:0035613 | RNA stem-loop binding | molecular_function | Binding to a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop. [GOC:sart, PMID:16568238, PMID:20455544] |
| GO:0061630 | ubiquitin protein ligase activity | molecular_function | Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S = X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond |
| GO:1905762 | CCR4-NOT complex binding | molecular_function | Binding to a CCR4-NOT complex. [GOC:TermGenie, PMID:26942678] |
| GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | biological_process | The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins. [GOC:krc, GOC:ma, PMID:10025395] |
| GO:0000209 | protein polyubiquitination | biological_process | Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain. [ISBN:0815316194] |
| GO:0000956 | nuclear-transcribed mRNA catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells. [GOC:krc] |
| GO:0001782 | B cell homeostasis | biological_process | The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. [GOC:add, ISBN:0781735149, PMID:12956429] |
| GO:0002634 | regulation of germinal center formation | biological_process | Any process that modulates the frequency, rate, or extent of germinal center formation. [GOC:add] |
| GO:0002635 | negative regulation of germinal center formation | biological_process | Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation. [GOC:add] |
| GO:0010608 | post-transcriptional regulation of gene expression | biological_process | Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript. [GOC:dph, GOC:tb] |
| GO:0030889 | negative regulation of B cell proliferation | biological_process | Any process that stops, prevents or reduces the rate or extent of B cell proliferation. [GOC:mah] |
| GO:0033962 | P-body assembly | biological_process | The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body. [GOC:mah, PMID:17429074] |
| GO:0042098 | T cell proliferation | biological_process | The expansion of a T cell population by cell division. Follows T cell activation. [GOC:jl] |
| GO:0043029 | T cell homeostasis | biological_process | The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. [GOC:mgi_curators, ISBN:0781735149] |
| GO:0043488 | regulation of mRNA stability | biological_process | Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs. [GOC:jl] |
| GO:0045623 | negative regulation of T-helper cell differentiation | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper cell differentiation. [GOC:go_curators] |
| GO:0046007 | negative regulation of activated T cell proliferation | biological_process | Any process that stops, prevents or reduces the rate or extent of activated T cell proliferation. [GOC:go_curators] |
| GO:0048535 | lymph node development | biological_process | The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes. [GOC:add, ISBN:068340007X, ISBN:0781735149] |
| GO:0048536 | spleen development | biological_process | The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions. [GOC:add, ISBN:0781735149] |
| GO:0050852 | T cell receptor signaling pathway | biological_process | The series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell. [GOC:add] |
| GO:0050856 | regulation of T cell receptor signaling pathway | biological_process | Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell. [GOC:ai] |
| GO:0061158 | 3'-UTR-mediated mRNA destabilization | biological_process | An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA. [GOC:dph, GOC:jh] |
| GO:0061470 | T follicular helper cell differentiation | biological_process | The process in which a relatively unspecialized T cell acquires specialized features of a mature T follicular helper cell. [GOC:dph, PMID:21572431] |
| GO:0071347 | cellular response to interleukin-1 | biological_process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus. [GOC:mah] |
| GO:1900151 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | biological_process | Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. [GOC:mcc, GOC:TermGenie] |
| GO:1901224 | positive regulation of non-canonical NF-kappaB signal transduction | biological_process | Any process that activates or increases the frequency, rate or extent of the non-canonical NF-kappaB cascade. [GOC:TermGenie] |
| GO:2000320 | negative regulation of T-helper 17 cell differentiation | biological_process | Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differentiation. [GOC:BHF, GOC:mah] |
| GO:2000628 | regulation of miRNA metabolic process | biological_process | Any process that modulates the frequency, rate or extent of miRNA metabolic process. [GOC:dph] |
| GO:0000932 | P-body | cellular_component | A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing. [GOC:clt, PMID:12730603] |
| GO:0010494 | cytoplasmic stress granule | cellular_component | A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. [GOC:ans, PMID:17284590, PMID:17601829, PMID:17967451, PMID:20368989] |
| GO:0000288 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | biological_process | A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability. [GOC:jp, GOC:krc] |
| GO:0003729 | mRNA binding | molecular_function | Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. [GOC:kmv, GOC:pr, SO:0000234] |
| GO:0006511 | ubiquitin-dependent protein catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein. [GOC:go_curators] |