| GO term | GO name | GO namespace | GO def |
| GO:0003924 | GTPase activity | molecular_function | Catalysis of the reaction |
| GO:0005096 | GTPase activator activity | molecular_function | Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP. [GOC:mah] |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:0007186 | G protein-coupled receptor signaling pathway | biological_process | The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. [GOC:bf, GOC:mah, PMID:16902576, PMID:24568158, Wikipedia:G_protein-coupled_receptor] |
| GO:0008277 | regulation of G protein-coupled receptor signaling pathway | biological_process | Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway. [GOC:go_curators] |
| GO:0009968 | negative regulation of signal transduction | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction. [GOC:sm] |
| GO:0005737 | cytoplasm | cellular_component | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684] |
| GO:0005886 | plasma membrane | cellular_component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |